ID   A0A183W1B2_TRIRE        Unreviewed;       452 AA.
AC   A0A183W1B2;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=Amiloride-sensitive sodium channel {ECO:0008006|Google:ProtNLM};
GN   ORFNames=TRE_LOCUS6518 {ECO:0000313|EMBL:VDQ02398.1};
OS   Trichobilharzia regenti (Nasal bird schistosome).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC   Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Trichobilharzia.
OX   NCBI_TaxID=157069 {ECO:0000313|WBParaSite:TRE_0000652301-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:TRE_0000652301-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (JUN-2016) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDQ02398.1, ECO:0000313|Proteomes:UP000280995}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the amiloride-sensitive sodium channel (TC
CC       1.A.6) family. {ECO:0000256|RuleBase:RU000679}.
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DR   EMBL; UZAO01056800; VDQ02398.1; -; Genomic_DNA.
DR   WBParaSite; TRE_0000652301-mRNA-1; TRE_0000652301-mRNA-1; TRE_0000652301.
DR   Proteomes; UP000280995; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005272; F:sodium channel activity; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.287.770; YojJ-like; 1.
DR   InterPro; IPR001873; ENaC.
DR   Pfam; PF00858; ASC; 1.
PE   3: Inferred from homology;
KW   Ion channel {ECO:0000256|RuleBase:RU000679};
KW   Ion transport {ECO:0000256|RuleBase:RU000679};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Reference proteome {ECO:0000313|Proteomes:UP000280995};
KW   Sodium {ECO:0000256|ARBA:ARBA00023053};
KW   Sodium channel {ECO:0000256|ARBA:ARBA00022461,
KW   ECO:0000256|RuleBase:RU000679};
KW   Sodium transport {ECO:0000256|ARBA:ARBA00023201,
KW   ECO:0000256|RuleBase:RU000679};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU000679};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW   Transport {ECO:0000256|RuleBase:RU000679}.
SQ   SEQUENCE   452 AA;  51654 MW;  CADF614DB2CF5BAA CRC64;
     MGQFHIEVRL AGVNQTLLGR PLIIAHEPNS FPFDNFGRYL YEFINPGTLV NIFYSKSITK
     RLNTRKNPCT SKSINLLGNY FDYDQITCQW HTVCAKYNQK CDCTCPLELL RLRLNREMKS
     KTRNRSIPSN YIISNNQTNY NCPLKCPIDI PIAFVNNSVC PLACRTVTYK KLNEVLDNIT
     DRSTIQLELI QAEGLTEMTE EALYSLPKLF SEIGGLSSFC FGFSCILFFE LIELVFWLRC
     TFCSNFIERV KEILGQQIEI TDDTNKFMKN NDNNTSKIFS TKKESQKHED MIYNDNENSK
     INSNKSKQQR KRLFKASAFS SKCMSSNPFK VKSNKHSTTC NPTRLKXXXX XXXXXXXXXX
     XXXXXXXXXX XXXXXXXXLS EYPKDQDSPL IGLKSIKHSL LDDSTLGKNL NSSSLTQYPM
     NSPTVSTSFP ISTVPVILNN HLFQVVVDYE IS
//