ID A0A183W1S4_TRIRE Unreviewed; 209 AA.
AC A0A183W1S4;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=VPS37 C-terminal domain-containing protein {ECO:0000313|WBParaSite:TRE_0000668501-mRNA-1};
GN ORFNames=TRE_LOCUS6681 {ECO:0000313|EMBL:VDQ02561.1};
OS Trichobilharzia regenti (Nasal bird schistosome).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Trichobilharzia.
OX NCBI_TaxID=157069 {ECO:0000313|WBParaSite:TRE_0000668501-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:TRE_0000668501-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (JUN-2016) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDQ02561.1, ECO:0000313|Proteomes:UP000280995}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Component of the ESCRT-I complex, a regulator of vesicular
CC trafficking process. Required for the sorting of endocytic
CC ubiquitinated cargos into multivesicular bodies. May be involved in
CC cell growth and differentiation. {ECO:0000256|ARBA:ARBA00025010}.
CC -!- SIMILARITY: Belongs to the VPS37 family.
CC {ECO:0000256|ARBA:ARBA00007617}.
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DR EMBL; UZAO01057149; VDQ02561.1; -; Genomic_DNA.
DR STRING; 157069.A0A183W1S4; -.
DR WBParaSite; TRE_0000668501-mRNA-1; TRE_0000668501-mRNA-1; TRE_0000668501.
DR Proteomes; UP000280995; Unassembled WGS sequence.
DR GO; GO:0000813; C:ESCRT I complex; IEA:UniProt.
DR GO; GO:0009056; P:catabolic process; IEA:UniProt.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.287.660; Helix hairpin bin; 1.
DR InterPro; IPR037202; ESCRT_assembly_dom.
DR InterPro; IPR029012; Helix_hairpin_bin_sf.
DR InterPro; IPR009851; Mod_r.
DR PANTHER; PTHR13678:SF27; LD45836P; 1.
DR PANTHER; PTHR13678; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37; 1.
DR Pfam; PF07200; Mod_r; 1.
DR SUPFAM; SSF140111; Endosomal sorting complex assembly domain; 1.
DR PROSITE; PS51314; VPS37_C; 1.
PE 3: Inferred from homology;
KW Endosome {ECO:0000256|ARBA:ARBA00022753};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000280995};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 66..155
FT /note="VPS37 C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51314"
SQ SEQUENCE 209 AA; 23681 MW; 639BF41726017360 CRC64;
MGATNYNGLD NKDEILSTLE KKIEADKEVC MNENRRQAEA NLALEPTFNM KKTELVETYA
TYRQLEIQYM KIKSEVDSIG AKYSPSVILA LLQTANAESE EQSEELANRF LDKSMDVDTF
LKEFIPLRKL CNERRFKCEK LSEQISTGQI SEPNLPSTNH MSYLPNMMKM MNTDSSGSTS
QLYPSLLSLS NSNNNSNNYS TASSYGFNI
//
