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Database: UniProt
Entry: A0A191TGK9_9BACT
LinkDB: A0A191TGK9_9BACT
Original site: A0A191TGK9_9BACT 
ID   A0A191TGK9_9BACT        Unreviewed;       476 AA.
AC   A0A191TGK9;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   13-FEB-2019, entry version 20.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01081161};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=A9P82_00005 {ECO:0000313|EMBL:ANI87844.1};
OS   Arachidicoccus sp. BS20.
OC   Bacteria; Bacteroidetes; Chitinophagia; Chitinophagales;
OC   Chitinophagaceae; Arachidicoccus.
OX   NCBI_TaxID=1850526 {ECO:0000313|EMBL:ANI87844.1};
RN   [1] {ECO:0000313|EMBL:ANI87844.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BS20 {ECO:0000313|EMBL:ANI87844.1};
RA   Im W.T., Siddiqi M.Z.;
RT   "Arachidicoccus sp. BS20 whole genome sequincing.";
RL   Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756121}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS01082709}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; CP015971; ANI87844.1; -; Genomic_DNA.
DR   RefSeq; WP_066202625.1; NZ_CP015971.1.
DR   EnsemblBacteria; ANI87844; ANI87844; A9P82_00005.
DR   KEGG; arb:A9P82_00005; -.
DR   KO; K02313; -.
DR   OrthoDB; 219876at2; -.
DR   BioCyc; GCF_001659705:G1EUG-1-MONOMER; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   Gene3D; 3.30.300.180; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR038454; DnaA_N_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756129};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS01082702};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00756116};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01082706};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756117}.
FT   DOMAIN      170    300       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      381    450       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     178    185       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   476 AA;  54903 MW;  806901B9F482D20C CRC64;
     MSKTAESVWA NCLDIIKDIV EWQHFKTWFE PIVPLQLKDN VLLIQVPSNF FYEYLEEHYV
     SLLAKTLKRQ LGRDARLEYR IMIDSGNTTD KGYMKVPSGE EKTHANTLVL PMKINDTNGL
     NPFIVPGIKR MQIDPQLNSE DTFEKFVEGD CNRVARRAGK TVAEKPGNNS FNPLFIYGGS
     GLGKTHLLHA IGNEVKKLHP NKVVLYVSSE KFINQFQHHS RNNQINDFIN FYQLIDVLLI
     DDVQFFNRAE KSQDAFFAIF NHLQQSGKQL VLTSDKAPKD LDGLQERLLS RFRWGLSADV
     QVPDYETRIE IFEQKMREEG LEMPKEVVKY VAYNLTSNVR ELRGALISLL AQSSLNKRDI
     DIDLAKKVLR NIIKTNNKEV TIDAIQKMVC EYFDVPYNRL LEKTRKREVV QARQITMYLS
     KTFTKNSLKT IGEHFGGRDH TTVIHSCQTV KDLMDTDSVF KENVMELTQK VQLASM
//
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