ID A0A191V4A7_9ACTN Unreviewed; 476 AA.
AC A0A191V4A7;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Ketosynthase family 3 (KS3) domain-containing protein {ECO:0000259|PROSITE:PS52004};
GN ORFNames=GCM10010220_49550 {ECO:0000313|EMBL:GGR91142.1},
GN Spa2297_23940 {ECO:0000313|EMBL:ANJ09755.1};
OS Streptomyces parvulus.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=146923 {ECO:0000313|EMBL:ANJ09755.1, ECO:0000313|Proteomes:UP000078468};
RN [1] {ECO:0000313|EMBL:ANJ09755.1, ECO:0000313|Proteomes:UP000078468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2297 {ECO:0000313|EMBL:ANJ09755.1,
RC ECO:0000313|Proteomes:UP000078468};
RA Nishizawa T., Miura T., Harada C., Guo Y., Narisawa K., Ohta H.,
RA Takahashi H., Shirai M.;
RT "Non-Contiguous Finished Genome Sequence of Streptomyces parvulus 2297
RT Integrated Site-Specifically with Actinophage R4.";
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:GGR91142.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=JCM 4068 {ECO:0000313|EMBL:GGR91142.1};
RX PubMed=30832757;
RA Wu L., Ma J.;
RT "The Global Catalogue of Microorganisms (GCM) 10K type strain sequencing
RT project: providing services to taxonomists for standard genome sequencing
RT and annotation.";
RL Int. J. Syst. Evol. Microbiol. 69:895-898(2019).
RN [3] {ECO:0000313|EMBL:GGR91142.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=JCM 4068 {ECO:0000313|EMBL:GGR91142.1};
RA Sun Q., Ohkuma M.;
RL Submitted (DEC-2022) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP
CC synthases family. {ECO:0000256|RuleBase:RU003694}.
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DR EMBL; CP015866; ANJ09755.1; -; Genomic_DNA.
DR EMBL; BMRX01000012; GGR91142.1; -; Genomic_DNA.
DR RefSeq; WP_064730073.1; NZ_CP015866.1.
DR AlphaFoldDB; A0A191V4A7; -.
DR KEGG; spav:Spa2297_23940; -.
DR Proteomes; UP000078468; Chromosome.
DR Proteomes; UP000645274; Unassembled WGS sequence.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:UniProt.
DR CDD; cd00833; PKS; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR43775; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR43775:SF37; FATTY ACID SYNTHASE; 1.
DR Pfam; PF00109; ketoacyl-synt; 1.
DR Pfam; PF02801; Ketoacyl-synt_C; 1.
DR SMART; SM00825; PKS_KS; 1.
DR SUPFAM; SSF53901; Thiolase-like; 1.
DR PROSITE; PS52004; KS3_2; 1.
PE 3: Inferred from homology;
KW Transferase {ECO:0000256|RuleBase:RU003694}.
FT DOMAIN 14..433
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
FT REGION 435..476
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 476 AA; 49084 MW; F7DB5C15A8F74BDF CRC64;
MSPQSSEADH IPKADPVAVI GIGCRLPGAH GPGRLWELLR AGQDATGVAP ADRFPAGTTP
PAGGARGGFV HGVDEFDAEF FGVTADEAAT MDPQQRLLLH TAWEALEDAG RDPGDLAGSA
TAVFVGQSHA DHWDRLRETR AGRLDLDCLV GGHQRSMLAG RLSFHLGLHG PSVTVDCAQA
SSLAAVHLAC LSLRAGESAL ALAGGANLVL GTTATEVFDG AGVLSSDGRC RFGDGAADGF
VRSDGVAVVV LKRLDRALAD GDPVRAVILG SALGHDGATK RHVTDPSVTG QSLVMRRAYR
SARVAPGDIG YVEAHGTGTR IDAVELDALN EVLAENRPQG RPCLVGSLKS NIGHCEAAAG
VAGLVKTVLC LEHREVPPTL HADTPSPLID WDRLPLVLPD STRPWPAFAG RPALAAVNGQ
GMSGVNAHLV IGPGPAEHTG AVRGRSTAGR VRPAPRHGRP TGRRPSSATA PAARAD
//
