ID   A0A191V6D2_9ACTN        Unreviewed;       319 AA.
AC   A0A191V6D2;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Bile acid:sodium symporter {ECO:0000313|EMBL:ANJ10579.1};
GN   ORFNames=Spa2297_28530 {ECO:0000313|EMBL:ANJ10579.1};
OS   Streptomyces parvulus.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=146923 {ECO:0000313|EMBL:ANJ10579.1, ECO:0000313|Proteomes:UP000078468};
RN   [1] {ECO:0000313|EMBL:ANJ10579.1, ECO:0000313|Proteomes:UP000078468}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=2297 {ECO:0000313|EMBL:ANJ10579.1,
RC   ECO:0000313|Proteomes:UP000078468};
RA   Nishizawa T., Miura T., Harada C., Guo Y., Narisawa K., Ohta H.,
RA   Takahashi H., Shirai M.;
RT   "Non-Contiguous Finished Genome Sequence of Streptomyces parvulus 2297
RT   Integrated Site-Specifically with Actinophage R4.";
RL   Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; CP015866; ANJ10579.1; -; Genomic_DNA.
DR   RefSeq; WP_064730902.1; NZ_JAJVLA010000031.1.
DR   AlphaFoldDB; A0A191V6D2; -.
DR   KEGG; spav:Spa2297_28530; -.
DR   Proteomes; UP000078468; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   Gene3D; 1.20.1530.20; -; 1.
DR   InterPro; IPR002657; BilAc:Na_symport/Acr3.
DR   InterPro; IPR004710; Bilac:Na_transpt.
DR   InterPro; IPR038770; Na+/solute_symporter_sf.
DR   PANTHER; PTHR10361:SF28; RH04535P; 1.
DR   PANTHER; PTHR10361; SODIUM-BILE ACID COTRANSPORTER; 1.
DR   Pfam; PF01758; SBF; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        21..44
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        50..67
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        79..103
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        109..129
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        136..157
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        177..194
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        206..226
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        232..255
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   319 AA;  32626 MW;  10CA374A70C1E76C CRC64;
     MRTERPEQAS TDVPADRSAR RAVTVFPILV LVAGALGLLL PGGFAGWGEA VPYLLGVVMF
     CMGITMTPED FRGVAKRPWA VALGLVAHYV IMPGLGWAIA HLLDLPPQLA AGVILVGCAP
     SGTASNVVTY LARGDVALSV SVATVSTLVA PLVTPPLTLL LAGEYLPVDA GSMVTDILKT
     VLLPVLAGVV VRLLAGRYVQ RALPALPWLS ALTIAVIVAV VVAGSADAIK SAAGLVFVAV
     VLHNGLGLAL GYGAGRLGRL GEPGSRAMAF EVGMQNSGLA ASLATAHFSP LAALPAAVFS
     VWHNVSGAVT AAWLSRRGR
//