ID A0A191VAH5_9ACTN Unreviewed; 450 AA.
AC A0A191VAH5;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Crotonyl-CoA carboxylase/reductase {ECO:0000313|EMBL:ANJ11878.1};
DE SubName: Full=Crotonyl-CoA reductase {ECO:0000313|EMBL:GGR98860.1};
GN ORFNames=GCM10010220_59240 {ECO:0000313|EMBL:GGR98860.1},
GN Spa2297_32695 {ECO:0000313|EMBL:ANJ11878.1};
OS Streptomyces parvulus.
OG Plasmid pSPA1 {ECO:0000313|EMBL:ANJ11878.1}, and
OG Plasmid pspa1 {ECO:0000313|Proteomes:UP000078468}.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=146923 {ECO:0000313|EMBL:ANJ11878.1, ECO:0000313|Proteomes:UP000078468};
RN [1] {ECO:0000313|EMBL:ANJ11878.1, ECO:0000313|Proteomes:UP000078468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2297 {ECO:0000313|EMBL:ANJ11878.1,
RC ECO:0000313|Proteomes:UP000078468};
RC PLASMID=pspa1 {ECO:0000313|Proteomes:UP000078468}, and pSPA1
RC {ECO:0000313|EMBL:ANJ11878.1};
RA Nishizawa T., Miura T., Harada C., Guo Y., Narisawa K., Ohta H.,
RA Takahashi H., Shirai M.;
RT "Non-Contiguous Finished Genome Sequence of Streptomyces parvulus 2297
RT Integrated Site-Specifically with Actinophage R4.";
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:GGR98860.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=JCM 4068 {ECO:0000313|EMBL:GGR98860.1};
RX PubMed=30832757;
RA Wu L., Ma J.;
RT "The Global Catalogue of Microorganisms (GCM) 10K type strain sequencing
RT project: providing services to taxonomists for standard genome sequencing
RT and annotation.";
RL Int. J. Syst. Evol. Microbiol. 69:895-898(2019).
RN [3] {ECO:0000313|EMBL:GGR98860.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=JCM 4068 {ECO:0000313|EMBL:GGR98860.1};
RA Sun Q., Ohkuma M.;
RL Submitted (DEC-2022) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP015867; ANJ11878.1; -; Genomic_DNA.
DR EMBL; BMRX01000017; GGR98860.1; -; Genomic_DNA.
DR RefSeq; WP_064732205.1; NZ_CP015867.1.
DR AlphaFoldDB; A0A191VAH5; -.
DR KEGG; spav:Spa2297_32695; -.
DR Proteomes; UP000078468; Plasmid pspa1.
DR Proteomes; UP000645274; Unassembled WGS sequence.
DR GO; GO:0043880; F:crotonyl-CoA reductase activity; IEA:InterPro.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 2.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR010085; Crot_CoA_red.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR NCBIfam; TIGR01751; crot-CoA-red; 1.
DR PANTHER; PTHR44154; QUINONE OXIDOREDUCTASE; 1.
DR PANTHER; PTHR44154:SF1; QUINONE OXIDOREDUCTASE; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Plasmid {ECO:0000313|EMBL:ANJ11878.1}.
FT DOMAIN 49..415
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 450 AA; 49516 MW; 0E3EC7E6D293E787 CRC64;
MDEIINAVSR GDASSEDFGG LRLPDSYRGA VVRREDVAMF EGIASRDKDP RKSLQIQDVP
VPLPGPGEAL VAVMASSVNY NTVWSSIFEP LPTFGFLERY ARLSPHAARH DQPYHVLGSD
LAGVVLRTGP GVNRWRPGDR VVAHCLSVEL ESADGHDDTM LDPEQRIWGF ETNFGGLAEL
ALVKSNQLMP KPGHLSWEEA AAPGLVNSTA YRQLVSRNGA GMKQGDNVLI WGASGGLGSY
ATQLALAGGA NPVCVVSSEQ KAEICRAMGA EAVIDRDAED YRFWKDEETQ DPREWKRFGK
RIRELTGGED VDIVFEHPGR ETFGASVYVT RKGGTVVTCA STSGFRHEYD NRYLWMSLKR
IVGSHFANYR EAWEANRLVV KGKIHPTLSR VYPLEETGQA AYDVHRNLHQ GKVGVLCLAP
EEGLGVTDHD LRARHIGAIN RFREGQAPTP
//
