ID A0A192H410_9LACO Unreviewed; 234 AA.
AC A0A192H410;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Competence protein ComE {ECO:0000313|EMBL:ANK63105.1};
DE SubName: Full=Helix-hairpin-helix domain-containing protein {ECO:0000313|EMBL:MDA5387109.1};
GN ORFNames=AYR53_10235 {ECO:0000313|EMBL:ANK63105.1}, OUQ91_002258
GN {ECO:0000313|EMBL:MDA5387109.1};
OS Loigolactobacillus backii.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Loigolactobacillus.
OX NCBI_TaxID=375175 {ECO:0000313|EMBL:ANK63105.1, ECO:0000313|Proteomes:UP000078582};
RN [1] {ECO:0000313|EMBL:ANK63105.1, ECO:0000313|Proteomes:UP000078582}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TMW 1.1989 {ECO:0000313|EMBL:ANK63105.1,
RC ECO:0000313|Proteomes:UP000078582};
RA Behr J., Geissler A.J., Vogel R.F.;
RT "Pediococcus and Lactobacillus from brewery environment - whole genome
RT sequencing and assembly.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:MDA5387109.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=KKP 3565 {ECO:0000313|EMBL:MDA5387109.1};
RG Lg backii sequencing group;
RA Kiousi D.E., Bucka Kolendo J.;
RL Submitted (NOV-2022) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP014873; ANK63105.1; -; Genomic_DNA.
DR EMBL; JAPTYS010000006; MDA5387109.1; -; Genomic_DNA.
DR RefSeq; WP_068280396.1; NZ_JAPTYT010000006.1.
DR AlphaFoldDB; A0A192H410; -.
DR STRING; 375175.AYR53_10235; -.
DR GeneID; 42982635; -.
DR Proteomes; UP000078582; Chromosome.
DR Proteomes; UP001150357; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR Gene3D; 1.10.150.280; AF1531-like domain; 1.
DR Gene3D; 3.10.560.10; Outer membrane lipoprotein wza domain like; 1.
DR InterPro; IPR004509; Competence_ComEA_HhH.
DR InterPro; IPR003583; Hlx-hairpin-Hlx_DNA-bd_motif.
DR InterPro; IPR010994; RuvA_2-like.
DR InterPro; IPR019554; Soluble_ligand-bd.
DR NCBIfam; TIGR00426; competence protein ComEA helix-hairpin-helix repeat region; 1.
DR PANTHER; PTHR21180; ENDONUCLEASE/EXONUCLEASE/PHOSPHATASE FAMILY DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR21180:SF32; ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE FAMILY DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF12836; HHH_3; 1.
DR Pfam; PF10531; SLBB; 1.
DR SMART; SM00278; HhH1; 2.
DR SUPFAM; SSF47781; RuvA domain 2-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000078582};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..33
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 182..201
FT /note="Helix-hairpin-helix DNA-binding motif class 1"
FT /evidence="ECO:0000259|SMART:SM00278"
FT DOMAIN 212..231
FT /note="Helix-hairpin-helix DNA-binding motif class 1"
FT /evidence="ECO:0000259|SMART:SM00278"
FT REGION 146..171
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 150..171
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 234 AA; 25276 MW; 6F5855DC21F7C2C6 CRC64;
MSTDWLSLIK RYWYCGVIGL LLVIIGIIGY QAMFQRPVTK NEAVFSNSSV IQDSSTSAQY
QNTATEAQQT GQTIQKGFVD VKGAVKKPGI YVVTDNTRLF DVIRKAGGLA EDADQKQVNL
AQQVSDQQII FIPKVGEEVP AELGLAEQQP TPAESGSTIA TTGSADGQQA TGQTNLNTAT
AEELQQLTGI GQKKAELIIN FRTEQGGFKQ IEDLKKVSGI GEKTFESLKD SITV
//
