ID A0A193GBN7_9BORD Unreviewed; 3979 AA.
AC A0A193GBN7;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=Carrier domain-containing protein {ECO:0000259|PROSITE:PS50075};
GN ORFNames=BAU07_09105 {ECO:0000313|EMBL:ANN77240.1};
OS Bordetella flabilis.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Alcaligenaceae; Bordetella.
OX NCBI_TaxID=463014 {ECO:0000313|EMBL:ANN77240.1, ECO:0000313|Proteomes:UP000091926};
RN [1] {ECO:0000313|EMBL:ANN77240.1, ECO:0000313|Proteomes:UP000091926}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AU10664 {ECO:0000313|EMBL:ANN77240.1,
RC ECO:0000313|Proteomes:UP000091926};
RA LiPuma J.J., Spilker T.;
RT "Complete genome sequences of Bordetella bronchialis and Bordetella
RT flabilis.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pantetheine 4'-phosphate; Xref=ChEBI:CHEBI:47942;
CC Evidence={ECO:0000256|ARBA:ARBA00001957};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP016172; ANN77240.1; -; Genomic_DNA.
DR RefSeq; WP_066656379.1; NZ_CP016172.1.
DR STRING; 463014.BAU07_09105; -.
DR KEGG; bfz:BAU07_09105; -.
DR Proteomes; UP000091926; Chromosome.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR GO; GO:0008610; P:lipid biosynthetic process; IEA:InterPro.
DR CDD; cd05930; A_NRPS; 1.
DR CDD; cd17643; A_NRPS_Cytc1-like; 2.
DR CDD; cd05931; FAAL; 1.
DR CDD; cd19531; LCL_NRPS-like; 2.
DR Gene3D; 3.30.300.30; -; 4.
DR Gene3D; 3.40.50.980; -; 4.
DR Gene3D; 1.10.1200.10; ACP-like; 4.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 3.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 2.
DR Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 3.
DR InterPro; IPR010071; AA_adenyl_domain.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR001242; Condensatn.
DR InterPro; IPR040097; FAAL/FAAC.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR NCBIfam; TIGR01733; AA-adenyl-dom; 2.
DR PANTHER; PTHR45527:SF1; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR Pfam; PF00501; AMP-binding; 5.
DR Pfam; PF13193; AMP-binding_C; 3.
DR Pfam; PF00668; Condensation; 3.
DR Pfam; PF00550; PP-binding; 4.
DR SMART; SM00823; PKS_PP; 4.
DR SMART; SM01294; PKS_PP_betabranch; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 4.
DR SUPFAM; SSF47336; ACP-like; 4.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 6.
DR PROSITE; PS00455; AMP_BINDING; 2.
DR PROSITE; PS50075; CARRIER; 4.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 3.
PE 4: Predicted;
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553}.
FT DOMAIN 593..668
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 1691..1766
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 2769..2843
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 3878..3953
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT REGION 2840..2871
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3617..3636
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3979 AA; 430197 MW; 3232925181996C16 CRC64;
MADIALSSDN VATILAERAL RHPDKPALKF LGDGESVTAQ LSYAELDEQV RSLALRLADA
AAPGDRALLL YPSGPAYAVA FIACLRAGVI AVPAYPPESA SPQHAGRLAA ILRDAQPTLV
LTEARLLPLL APLAAAAGQP GPSLMATDTF PAEADVRDSA RSPGGDAVAF LQYTSGSTSR
PKGVRVTHRN LVANEAAIQR AFGIGQDDTI VSWLPLYHDM GLIGGLLQPL FSGVTVVLMS
PAHFLERPVR WLQAMARYGG TVSGGPDFAF RLCAARIGAE QAASLDLSRW RLAFLGSEPI
RAHTLEAFEK AFAPAGFQRR AFYPCYGLAE ATLFATGGRP GGGFHAVTVD RERLAGGELV
GTAEGLALVG VGTAQDGHAT RIVDPATGAG LTDGRVGEIW LAGPSVAAGY WGDDRASADT
FVAVDGRAWL RTGDLGAMHQ GALFVTGRLK DMIIVRGQNL YPPDIEAIVE MQVDVVRKGR
VVAFGVETEA GEGIGIAAEI SPGVRKLVAP EQLRDAIAEA VVLTHRESPA VVALLNPGAL
PRTTSGKLQR LACRAQWMDG TLDSYAVYRD GATEALSPAA RAGSDLGDAA GTEDREALAR
DIAHVWAAVL RRKSLRPTDR FTALGGSSLA AAQAAAMLQD RFGIEVPLHW FFEAPTPREF
AVRMEEAMAA SLPADRDARA ERPRAQDAGA LPRACPDPAA ALPLAWSYPA SPAQQRMFFF
WRMEPDSGAY HIAGSLRLHG PLDAARVERV LAALARRHES LRSRFAEAGD TLACHVDAPA
ATVLECDDLR AHPAAQRQAI VEDILRIVAR RPFDLIRGPL WRARLLRLGE EEHLLAVAVH
HIVADGQSMN ILIRDFGALY ARAARDTTPL LPRPPARYAD YAEATRARLA DGTMAAQLAW
WTGHLGPDVP VLALPLDRPR PAVQTYTGAL HRFTIDAALA RRIRQFAAAH DVSVFMVLLS
GFDVLLHRYT GQREVRVGVP FANRTASAWR DVVGLFVNTV VIPSRWDASR DYAAFLQEVR
HAVVQGQAHA DLPFERLVEA LNPDRSLAHH PLFQAMYNHL EHPADENALP GLRVAARSED
AGITKFDLGL NTEAHADGGL SGSWVYAADL FEPATIARMA AHYLALLDAL TGRPHIPLGQ
VEFLGDDERR QLLAWSHGPA QEESIPPVHA QIARQASRTP DAVALVQGDA MLTYSAMMAR
ARALSAQLAR HGAGPETRIG VLARRSLDLP VLLLAILQSG AAYVPLDPDH PAARLADVAR
RADLQFVVRS CAADVTLVSE TSVLDLDALL TEDAASMRAA PAAPDATVAT TAPDALAYIL
FTSGTTGRPK GVGITHGALA RRLAWMQREY SLSADETLLQ KTPMGFDVSV WEIFWPLTQG
ARLAIADPED HRDPARLAAL VHRHGVSTLH FVPSMLERFL EQADDAQCAS LTRLFSGGEA
LARPLCDRVL ARWPNIRFDN RYGPTEALIN ATAWRCVSDA GHTVPIGRPL PDTAIHILDD
ALNAVPVGVA GHLHIGGATL ARGYLDDPGL TADRFIPDPH GKGRRLYRSG DLARWRADGA
LEYLGRADDQ VKIRGHRIEV GEVQAQLREL DLVRDAAVIA HAGPDGLLRL VAYVVPAETA
AHDRAATGTA ASACAAVPAV TAIREAMARR VPSHMVPALV MVLEALPLTP TGKLDRAALP
APVWESLDYV APGTGIERAV ADIWREVLGV TRIGLADDFF ALGGHSLLAT QVVARLRRRF
GIDLPLRTLF EGPVLATFAT AVQKEIDAGA VPTRPEPVRS PRGDRLPLSY SQERMWFLWN
MEPDGAAYNV GGAVRLSGPL DVHAMRTAFH ALLMRHEALR TTFPAVDGAP TQRIHPRPDA
ALAVVDLGDM APAEQARHVA AFAHDEAHRP FDLADGPLLR ATLLRLAPDR HMLVITLHHI
IAEGWAMEVF ADEYAHLYRD VVGGRTPSLP PPDLQYADFA VWQRAWLDGG EADRQLAYWT
ETLGTDHPVL DLPTDRPRPP VRSFAGDALT FDMDDALLAR VRRFNARHGS TLFMTVVAAT
LAWLHRYSGQ SDLRVGYPIA NRTHLAFEGM VGGFLNTQVL RCRVEGAMTA RGLLHAVRAA
SLGAQSHQDV PYHRIVDAVQ PRRSAAWSPL FQVMCNVQRW KFQQTREVAP GLTAAFLPND
SKTAKFDLLL DVTDIDDRLS CVLTYSTDLF ERDTIARMAR HWRAILEGMV DEPDARIGEL
PLLAAAERHA AILRWNPPHE ARPPCGAAAT LHERIQAQAR RAPDAVAVVD GDRVLTYAQL
NALANQLAHH LRDAGVAPEA LVGLALERSL DVVVGMLAIL KAGAAYLPLD PGYPAAHLAR
LMDDARPVLV LTHSGLLSAL PLGNIPVWCF DRDVAALHGR SEDDLDIAVP AQALAYCIYT
SGSTGAPKGT LVTHANVTRL FDATGPVFRF DESDTWTLFH SYAFDFSVWE IFGALLHGGR
LVVLPRAVSR APSDLVRQLV EQGVTVLNQT PSAFRQLLAE PGLWARRAEL RLRHVIFGGE
ALDATVLRSW FDRFDADAPR LTNMYGITET TVHVTHHRLG PDDTAHARAP IGAAIADLRW
YVLDDAMSPV PPGVIGQLYV GGPGLARGYL GRPGLTAQRF VPDPYASEPG ARLYRTGDLA
RARPDGRVEY LGRADAQVKV RGFRIEPGEI EARLRELPGV RDAAVIVRED DGVSRLVAYL
VAAAHSADDP AHAEALATDI RRDLAQCLPD HMLPHACVVL PALPLTQNGK LDRQALPAPA
RHGARSGHGP RNAAEGLLAG LWAKVLERVD VGVEDNFFEL GGDSISAVRM VSLAREHGLR
MTPQDVFQYQ TIASLARHVG GQGAPAAEGG GRADTGRAAG LPPATSHGGG RASAYPLTPM
QEGILYHSRL QQSRGTYIVQ CDCDIAAELD VEAFRAAWTH ALRTHDILRT AFLDEGGGRP
LQQPLDEVAL PFTELCWDHL DPAERDARLR ELLREDFTQD FDLRTPPLMR IVLVRLAADK
YHLVWTHHHL LMDAWSVDAL LAEVLSSYHR IVSGDAPEAR PATPFRAYVE WVLGQDRGAA
AAYWRDALRG LREPMLLSRV ARPLGADDAS SLGRLDRRLS TEATKRLAAY AQARHVTLNT
VVQGAALLAL ASLARHGQPV LGVTVAGRHA PVPGILDMKG LFINTVPLSM PIDPHQPADA
WLRDVQQRNL GLREHAFLSL VDIHGCCDVP REMPLFDVIF VFENHPVGDA LRRDMARLGV
QGVDSRHRNG YPCTVIVWPE DELRFLILHE NRIIDPAQAA AFFERIVAVL EQWVADPGAT
LGAADFAGGR ALATPPALPA HAETGLHRAI EHWAARTPDA IAVVHEDQRL TYAELNARAN
HLAYRLMDMG VGPDRLVGLA LARSTELIVA MLATLKAGGA YLPLDPDYPA QRLAYLLDDA
APAAVIAHTR HAAGLADMAP SIPVLHIDGA DAGAIEARNP ERAVHADQLA YCIYTSGSTG
RPKGALLTHR NAVRLFDTVR EHFDFGAGDV WTLFHSYAFD FSVWEIFGAL RHGGRLAIVP
NPDSRSPQAF LRLLQRERVT VLNQTPSAFR QLLDAPGAGP ALREVPLRYV IFGGEALDPR
MLAPWLADPV ADAPRAAQAT RDANDPLAGG AGQARRGPRM VNMYGITETT VHVTHHVLHA
ADAAGTRSPI GTALPDLGAR VLDARMNPVP PGFEGELYVT GPGLARGYLG RPGLTAERFV
PDPEGRDGAR LYRTGDLVRQ TADGGLEYLG RIDAQVKLRG FRIELGEVEA ALQGVADIRE
AAVVVQGEGA AQRLVAYVVR RTATTAGRPG RAADPAGSPA AGLADTLRTA LRQGLPAYMI
PAVFIELDRL PLTQNGKIDR RALPAVAAAA IEDSQDVQAA DEIEEMLAGI WCQVLERGQV
GVTRHFLDAG GHSLAAVRVA AYIRERLGVD VPMTLVFDLP TVRQQAEWVR QARRAGAGAE
ANADVDQMLA LLADMKGPE
//
