ID A0A193GGC0_9BORD Unreviewed; 495 AA.
AC A0A193GGC0;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE RecName: Full=Exopolyphosphatase {ECO:0000256|ARBA:ARBA00020416};
DE EC=3.6.1.11 {ECO:0000256|ARBA:ARBA00012451};
GN ORFNames=BAU07_20035 {ECO:0000313|EMBL:ANN79102.1};
OS Bordetella flabilis.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Alcaligenaceae; Bordetella.
OX NCBI_TaxID=463014 {ECO:0000313|EMBL:ANN79102.1, ECO:0000313|Proteomes:UP000091926};
RN [1] {ECO:0000313|EMBL:ANN79102.1, ECO:0000313|Proteomes:UP000091926}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AU10664 {ECO:0000313|EMBL:ANN79102.1,
RC ECO:0000313|Proteomes:UP000091926};
RA LiPuma J.J., Spilker T.;
RT "Complete genome sequences of Bordetella bronchialis and Bordetella
RT flabilis.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[phosphate](n) + H2O = [phosphate](n-1) + H(+) + phosphate;
CC Xref=Rhea:RHEA:21528, Rhea:RHEA-COMP:9859, Rhea:RHEA-COMP:14279,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:16838,
CC ChEBI:CHEBI:43474; EC=3.6.1.11;
CC Evidence={ECO:0000256|ARBA:ARBA00000209};
CC -!- SIMILARITY: Belongs to the GppA/Ppx family.
CC {ECO:0000256|ARBA:ARBA00007125}.
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DR EMBL; CP016172; ANN79102.1; -; Genomic_DNA.
DR RefSeq; WP_066661458.1; NZ_CP016172.1.
DR AlphaFoldDB; A0A193GGC0; -.
DR STRING; 463014.BAU07_20035; -.
DR KEGG; bfz:BAU07_20035; -.
DR OrthoDB; 9793035at2; -.
DR Proteomes; UP000091926; Chromosome.
DR GO; GO:0004309; F:exopolyphosphatase activity; IEA:UniProtKB-EC.
DR GO; GO:0006793; P:phosphorus metabolic process; IEA:InterPro.
DR Gene3D; 3.30.420.40; -; 1.
DR Gene3D; 3.30.420.150; Exopolyphosphatase. Domain 2; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR022371; Exopolyphosphatase.
DR InterPro; IPR048950; Ppx_GppA_C.
DR InterPro; IPR003695; Ppx_GppA_N.
DR InterPro; IPR030673; PyroPPase_GppA_Ppx.
DR NCBIfam; TIGR03706; exo_poly_only; 1.
DR PANTHER; PTHR30005; EXOPOLYPHOSPHATASE; 1.
DR PANTHER; PTHR30005:SF0; RETROGRADE REGULATION PROTEIN 2; 1.
DR Pfam; PF02541; Ppx-GppA; 1.
DR Pfam; PF21447; Ppx-GppA_III; 1.
DR PIRSF; PIRSF001267; Pyrophosphatase_GppA_Ppx; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
PE 3: Inferred from homology;
FT DOMAIN 22..304
FT /note="Ppx/GppA phosphatase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02541"
FT DOMAIN 312..479
FT /note="Ppx/GppA phosphatase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21447"
SQ SEQUENCE 495 AA; 55059 MW; 1CAF41DD23A3E087 CRC64;
MDHLLAAVDL GSNSFRLSIG RVVQQEGTAQ IYQIDRLKET VRLAAGLDAD KRLSPDAVER
AIEVLERFGE RLRSFHASRV RAVATNTFRV ARNTAEFLPR AESALGFPIE VIAGREEARL
IFSGVVHTLP PSPNKRLIID IGGGSTEVII GKGYEPGLMS SLYMGCVSYS RQFFGDGVVD
AYQMKLAELA ARREAEVIAK QYRKMGWKEA YGSSGTAKAL YAILTECGFS DRGITRAGLA
KLKDRIIRSG RVIPSELPGI KVERADVLPG GLAIMSALFD ELNIDVMHTG DGALRLGVLY
DLLGRDDEHD KRDESVRQFM KRYHIDANQA GRVRRAALAL FQELDIEGAE RGELAHALGW
AADLHEIGLS IAHNDYHKHS AYVLGNADMP GFSRDDQRLL ALLALGHHGK LGKLEPLVRS
RQEWLAILCL RLAVLLFRRR EDLPALPLTV SVRGDSIVVR VRQDWLTTHP LSDFTLRAEE
SEWRKVGFSF ELLEF
//
