ID A0A193K9U1_9VIBR Unreviewed; 421 AA.
AC A0A193K9U1;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 24-JAN-2024, entry version 36.
DE RecName: Full=Cell division protein FtsA {ECO:0000256|HAMAP-Rule:MF_02033, ECO:0000256|PIRNR:PIRNR003101};
GN Name=ftsA {ECO:0000256|HAMAP-Rule:MF_02033};
GN ORFNames=A6E01_02105 {ECO:0000313|EMBL:ANO32080.1}, BCU06_07475
GN {ECO:0000313|EMBL:PMK19746.1};
OS Vibrio breoganii.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Vibrio.
OX NCBI_TaxID=553239 {ECO:0000313|EMBL:ANO32080.1, ECO:0000313|Proteomes:UP000092018};
RN [1] {ECO:0000313|EMBL:ANO32080.1, ECO:0000313|Proteomes:UP000092018}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FF50 {ECO:0000313|EMBL:ANO32080.1,
RC ECO:0000313|Proteomes:UP000092018};
RA Hehemann J.-H., Arevalo P., Datta M.S., Yu X., Corzett C., Henschel A.,
RA Preheim S.P., Timberlake S., Alm E.J., Polz M.F.;
RT "Adaptive Radiation by Waves of Gene Transfer Leads to Fine-Scale Resource
RT Partitioning in Marine Microbes.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000235835}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=10N.261.54.C7 {ECO:0000313|Proteomes:UP000235835};
RA Kauffman K., Hussain F., Yang J., Arevalo P., Brown J., Cutler M.,
RA Kelly L., Polz M.F.;
RT "Nontailed viruses are major unrecognized killers of bacteria in the
RT ocean.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:PMK19746.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=10N.261.54.C7 {ECO:0000313|EMBL:PMK19746.1};
RA Kauffman K., Arevalo P., Polz M.F.;
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:PMK19746.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=10N.261.54.C7 {ECO:0000313|EMBL:PMK19746.1};
RX PubMed=29364876; DOI=.1038/nature25474;
RA Kauffman K.M., Hussain F.A., Yang J., Arevalo P., Brown J.M., Chang W.K.,
RA VanInsberghe D., Elsherbini J., Sharma R.S., Cutler M.B., Kelly L.,
RA Polz M.F.;
RT "A major lineage of non-tailed dsDNA viruses as unrecognized killers of
RT marine bacteria.";
RL Nature 554:118-122(2018).
CC -!- FUNCTION: Cell division protein that is involved in the assembly of the
CC Z ring. May serve as a membrane anchor for the Z ring.
CC {ECO:0000256|HAMAP-Rule:MF_02033, ECO:0000256|PIRNR:PIRNR003101}.
CC -!- SUBUNIT: Self-interacts. Interacts with FtsZ. {ECO:0000256|HAMAP-
CC Rule:MF_02033}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|HAMAP-Rule:MF_02033};
CC Peripheral membrane protein {ECO:0000256|HAMAP-Rule:MF_02033};
CC Cytoplasmic side {ECO:0000256|HAMAP-Rule:MF_02033}. Note=Localizes to
CC the Z ring in an FtsZ-dependent manner. Targeted to the membrane
CC through a conserved C-terminal amphipathic helix. {ECO:0000256|HAMAP-
CC Rule:MF_02033}.
CC -!- SIMILARITY: Belongs to the FtsA/MreB family. {ECO:0000256|HAMAP-
CC Rule:MF_02033, ECO:0000256|PIRNR:PIRNR003101}.
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DR EMBL; CP016177; ANO32080.1; -; Genomic_DNA.
DR EMBL; MCXF01000216; PMK19746.1; -; Genomic_DNA.
DR RefSeq; WP_017026847.1; NZ_SYVT01000004.1.
DR AlphaFoldDB; A0A193K9U1; -.
DR STRING; 553239.A6E01_02105; -.
DR GeneID; 77306612; -.
DR KEGG; vbr:A6E01_02105; -.
DR eggNOG; COG0849; Bacteria.
DR OrthoDB; 9810567at2; -.
DR Proteomes; UP000092018; Chromosome 1.
DR Proteomes; UP000235835; Unassembled WGS sequence.
DR GO; GO:0032153; C:cell division site; IEA:UniProtKB-UniRule.
DR GO; GO:0009898; C:cytoplasmic side of plasma membrane; IEA:UniProtKB-UniRule.
DR GO; GO:0043093; P:FtsZ-dependent cytokinesis; IEA:UniProtKB-UniRule.
DR Gene3D; 3.30.1490.110; -; 1.
DR Gene3D; 3.30.420.40; -; 2.
DR HAMAP; MF_02033; FtsA; 1.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR020823; Cell_div_FtsA.
DR InterPro; IPR003494; SHS2_FtsA.
DR NCBIfam; TIGR01174; ftsA; 1.
DR PANTHER; PTHR32432:SF4; CELL DIVISION PROTEIN FTSA; 1.
DR PANTHER; PTHR32432; CELL DIVISION PROTEIN FTSA-RELATED; 1.
DR Pfam; PF14450; FtsA; 1.
DR Pfam; PF02491; SHS2_FTSA; 1.
DR PIRSF; PIRSF003101; FtsA; 1.
DR SMART; SM00842; FtsA; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306, ECO:0000256|HAMAP-
KW Rule:MF_02033};
KW Cell division {ECO:0000256|ARBA:ARBA00022618, ECO:0000256|HAMAP-
KW Rule:MF_02033};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475, ECO:0000256|HAMAP-
KW Rule:MF_02033};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|HAMAP-Rule:MF_02033}.
FT DOMAIN 10..196
FT /note="SHS2"
FT /evidence="ECO:0000259|SMART:SM00842"
SQ SEQUENCE 421 AA; 45420 MW; 53E0ED9A665CC216 CRC64;
MTKGTDDNLI VGLDIGTAAV SALVGEILPD GQINIIGAGS SPSRGMDKGG VNDLDSVIKS
VERAVNQAEL MAEHKITNVY LSISGQHITS RIEKGMGTIS DEEVSQEDMD RAIHTARSIK
IGEEERILHV IPQEFKIDHL GGIKNPLGLS GVRMEVSVHM ISCHNDMARN VIKAVERCGL
SVEQLVFSGL AASDAVITED EKELGVCVVD IGAGTMDVAL WTGGALRHTE VFSYAGNSVT
SDIAFAFGTP INDAEEIKVK YGCAMSELVS KDDTVNVPSV GGRPSRSLQR QTLSEVIEPR
YTELMGLINQ AIENAQNKMR ENGVKHHHIA AGIVLTGGAS QIEGLAECAE RVFGNQVRIG
KPTEVKGLTD YVKEPYHSTA VGLLHYGKDS SFNDEGEYSE PKQSSLTGLF SKMRNWIQKE
F
//
