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Database: UniProt
Entry: A0A193LBE1_9GAMM
LinkDB: A0A193LBE1_9GAMM
Original site: A0A193LBE1_9GAMM 
ID   A0A193LBE1_9GAMM        Unreviewed;       448 AA.
AC   A0A193LBE1;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   16-JAN-2019, entry version 20.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01081161};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377,
GN   ECO:0000313|EMBL:ANO49812.1};
GN   ORFNames=BA177_00005 {ECO:0000313|EMBL:ANO49812.1};
OS   Woeseia oceani.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Chromatiales;
OC   Woeseiaceae; Woeseia.
OX   NCBI_TaxID=1548547 {ECO:0000313|EMBL:ANO49812.1, ECO:0000313|Proteomes:UP000092695};
RN   [1] {ECO:0000313|EMBL:ANO49812.1, ECO:0000313|Proteomes:UP000092695}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=XK5 {ECO:0000313|EMBL:ANO49812.1,
RC   ECO:0000313|Proteomes:UP000092695};
RA   Mu D., Du Z.;
RT   "Complete genome sequence of a deep-branching marine Gamma
RT   Proteobacterium Woeseia oceani type strain XK5.";
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756121}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS01082709}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; CP016268; ANO49812.1; -; Genomic_DNA.
DR   EnsemblBacteria; ANO49812; ANO49812; BA177_00005.
DR   KEGG; woc:BA177_00005; -.
DR   KO; K02313; -.
DR   Proteomes; UP000092695; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   Gene3D; 3.30.300.180; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR038454; DnaA_N_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756129};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000092695};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS01082702};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00756116};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01082706};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756117};
KW   Reference proteome {ECO:0000313|Proteomes:UP000092695}.
FT   DOMAIN      145    273       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      356    425       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     153    160       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
FT   COILED      307    327       {ECO:0000256|SAM:Coils}.
FT   COILED      340    360       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   448 AA;  50058 MW;  746AFC9B933086B1 CRC64;
     MQGNSSLWNR CVRDLQAELP EQQFNTWIRP LQAVEGEQTL RLLAPNRFVV DWLKQHYIEQ
     IHKLVEAIDD AMVVVIEVGS RQVPPEVKPN RAPGRSFAGN ATGPAPDPVV STLNPGFNFS
     SFVEGKSNQL ARAAASQVGE NPGKSYNPLF IYGGVGLGKT HLMQAIGNAM LAKNPGARVS
     YVHSERFVGD MVKGLQHNTI SAFKRSYRSL DALLIDDIQF FAGKERSQEE FFHTFNALLE
     GQKQIVLTCD RYPKEVHGLE ERLQSRFGWG LTVAIEPPEL ETSVAILMSK AEAAGVSLPE
     EVAFFIAKRI RSNVRELEGA LRRVMANSEF TGQPINLEFA KEALRDLLAL QERLVSIENI
     QKTVADYYKL RVADLLSKKR SRSVARPRQM AMALAKELTN HSLPEIGDAF GGRDHTTVLH
     GCRRIASLRE VEKRLDDDYL NLLRTLTG
//
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