ID A0A193LD41_9GAMM Unreviewed; 897 AA.
AC A0A193LD41;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN ORFNames=BA177_03780 {ECO:0000313|EMBL:ANO50445.1};
OS Woeseia oceani.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Chromatiales; Woeseiaceae;
OC Woeseia.
OX NCBI_TaxID=1548547 {ECO:0000313|EMBL:ANO50445.1, ECO:0000313|Proteomes:UP000092695};
RN [1] {ECO:0000313|EMBL:ANO50445.1, ECO:0000313|Proteomes:UP000092695}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=XK5 {ECO:0000313|EMBL:ANO50445.1,
RC ECO:0000313|Proteomes:UP000092695};
RA Mu D., Du Z.;
RT "Complete genome sequence of a deep-branching marine Gamma Proteobacterium
RT Woeseia oceani type strain XK5.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-
CC [protein]; Xref=Rhea:RHEA:17989, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC COMP:11604, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:83421, ChEBI:CHEBI:456216; EC=2.7.11.1;
CC Evidence={ECO:0000256|ARBA:ARBA00001433};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-
CC threonyl-[protein]; Xref=Rhea:RHEA:46608, Rhea:RHEA-COMP:11060,
CC Rhea:RHEA-COMP:11605, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216;
CC EC=2.7.11.1; Evidence={ECO:0000256|ARBA:ARBA00000775};
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DR EMBL; CP016268; ANO50445.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A193LD41; -.
DR STRING; 1548547.BA177_03780; -.
DR KEGG; woc:BA177_03780; -.
DR Proteomes; UP000092695; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-EC.
DR CDD; cd14014; STKc_PknB_like; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR43289; MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20-RELATED; 1.
DR PANTHER; PTHR43289:SF6; SERINE_THREONINE-PROTEIN KINASE NEKL-3; 1.
DR Pfam; PF00069; Pkinase; 1.
DR Pfam; PF13374; TPR_10; 1.
DR Pfam; PF13424; TPR_12; 1.
DR SMART; SM00220; S_TKc; 1.
DR SMART; SM00028; TPR; 5.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Reference proteome {ECO:0000313|Proteomes:UP000092695};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 416..440
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 106..391
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 336..355
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 136
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 897 AA; 97913 MW; DF8BD07B9DC859F0 CRC64;
MLETALGLSG DERDRYIARE CQGDEALQAE LLELIALDDD QTGGLHSAID GALRQALPSL
SGGQADSRGD GEQNSASLSD LSFFQSEEFR PQAVQTLNKG NRIGQFEIQR LLGSGGMGEV
YEALQLEPVQ RTVAVKVIRY GAQDPGIMAR FDSERQTLAL MSHPAIAAVY DAGYAPDGRP
YFAMELVDGV PIDAYLREHR LSLQKTLELL ISVCRGVQHA HQRGVIHRDL KPSNILVIEQ
DGRPTPKIID FGIAKAASTV NPDNEHMTQV GQLIGTLRYM SPEQADSMGV DVDTRSDVYA
VGTIFYEILT GRHPLNPEAM SSASFAERQR AFREYDPLPP SRVTDSSTPA ARSPSELKGD
LDWILLKALQ KDREQRYSSV GELARDLERH LKNEPVEASP PTARYRWSKF YRRNRIGVLA
AAAVTASIII GVAMGTVGFV RALAAEKEAV IQAEAAGEVS QFLVGLFEAS DPNKGGSADT
TARELLDRGA QQLDGRLNNQ PNTKAQLLQT LGNVYEILGL LNESFDKRFE AAQVLASLEN
ADPLRHASVL ADLSVSYRRR GDFQDAHDMA EKALATFHGT RSNDGAAESY ILSALGIAKL
TLGKYEEAEP VLQDSLRLVS DAAPGSAGHA TSAYNLAGLY NYMGRFSEAI PLVQQAIDIR
LQIDPDAPRI GDMYDGMGIL QLGLGQYGAA ADSMKKGLEA RRDYFGDDHY LVGLSLQNLA
EVAYVQGDYL ETAAMAAEAI SISERAEGDI EWRHLAAQYE LLAMASAPVG RLEQAYAAVS
RAKALRAEYT PEDHPDALLA EHAEAMVMLE DGHYGEAAER LERILEHRQT GISADGLDLY
EALVRAYTST EQYPRAEALC KQSAEKLDLQ NQADNLIAVR LKESCARFSR PTSNAAE
//
