ID   A0A194PDJ4_PAPXU        Unreviewed;       480 AA.
AC   A0A194PDJ4;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   SubName: Full=Lactase-phlorizin hydrolase {ECO:0000313|EMBL:KPI91416.1};
GN   ORFNames=RR46_14920 {ECO:0000313|EMBL:KPI91416.1};
OS   Papilio xuthus (Asian swallowtail butterfly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Papilionoidea;
OC   Papilionidae; Papilioninae; Papilio.
OX   NCBI_TaxID=66420 {ECO:0000313|EMBL:KPI91416.1, ECO:0000313|Proteomes:UP000053268};
RN   [1] {ECO:0000313|EMBL:KPI91416.1, ECO:0000313|Proteomes:UP000053268}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ya'a_city_454_Px {ECO:0000313|EMBL:KPI91416.1};
RC   TISSUE=Whole body {ECO:0000313|EMBL:KPI91416.1};
RX   PubMed=26354079; DOI=10.1038/ncomms9212;
RA   Li X., Fan D., Zhang W., Liu G., Zhang L., Zhao L., Fang X., Chen L.,
RA   Dong Y., Chen Y., Ding Y., Zhao R., Feng M., Zhu Y., Feng Y., Jiang X.,
RA   Zhu D., Xiang H., Feng X., Li S., Wang J., Zhang G., Kronforst M.R.,
RA   Wang W.;
RT   "Outbred genome sequencing and CRISPR/Cas9 gene editing in butterflies.";
RL   Nat. Commun. 6:8212-8212(2015).
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 1 family.
CC       {ECO:0000256|RuleBase:RU003690}.
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DR   EMBL; KQ459606; KPI91416.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A194PDJ4; -.
DR   STRING; 66420.A0A194PDJ4; -.
DR   Proteomes; UP000053268; Unassembled WGS sequence.
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 3.20.20.80; Glycosidases; 2.
DR   InterPro; IPR001360; Glyco_hydro_1.
DR   InterPro; IPR018120; Glyco_hydro_1_AS.
DR   InterPro; IPR033132; Glyco_hydro_1_N_CS.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   PANTHER; PTHR10353; GLYCOSYL HYDROLASE; 1.
DR   PANTHER; PTHR10353:SF36; KLOTHO (MAMMALIAN AGING-ASSOCIATED PROTEIN) HOMOLOG; 1.
DR   Pfam; PF00232; Glyco_hydro_1; 2.
DR   PRINTS; PR00131; GLHYDRLASE1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   PROSITE; PS00572; GLYCOSYL_HYDROL_F1_1; 1.
DR   PROSITE; PS00653; GLYCOSYL_HYDROL_F1_2; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000256|RuleBase:RU004468};
KW   Hydrolase {ECO:0000256|RuleBase:RU004468, ECO:0000313|EMBL:KPI91416.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053268}.
FT   ACT_SITE        374
FT                   /note="Nucleophile"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU10055"
SQ   SEQUENCE   480 AA;  55240 MW;  8563D20F41A4E363 CRC64;
     MTACEVNFSL NNAELARSRP FGNRPQGVSG YVDGSGLSNY SFPDDFIFGV ATAAFQIEGA
     WNIGSLKYYR MSISWPRILP QGTDNVINKD GVRYYRTLFK ELLKENITPV VTLFHWDLPT
     PLMDLGGWSN PKIIDYFEDY AKVAFTLFGD IIKLWSTMNE PHQHCSNGYG GDNFVPAMMS
     GGVGEYLCAH YMLLAHARAY HLYDKSFRPH QKGKIGITLD AFYAEPKDPT KQSDRDAAER
     YLQMHLGIFA HPIYSSMGDY PLLVRERINN ISLSQGFTRS RLPYFTSSEI DLLRGSSDFF
     GLNHYTTYLM SDMPMLQGWR VPSWDHDTGV LLEQNPLWPK PGADWLAVYP AGFRKVLNWI
     TRNYGTRIPI IVTENGVSDF GGLNDYARVS YYNNYLYQML LAMYEDGCNI QGYFAWTLMD
     DFEWKDGYTV KFGLFHVDFN STERTRIPKL SAFNYAEIVR RRRINFKYIE QIPKAHINIL
//