ID A0A194PH89_PAPXU Unreviewed; 567 AA.
AC A0A194PH89;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Glutamate receptor, ionotropic kainate 1 {ECO:0000313|EMBL:KPI92672.1};
GN ORFNames=RR46_13893 {ECO:0000313|EMBL:KPI92672.1};
OS Papilio xuthus (Asian swallowtail butterfly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Papilionoidea;
OC Papilionidae; Papilioninae; Papilio.
OX NCBI_TaxID=66420 {ECO:0000313|EMBL:KPI92672.1, ECO:0000313|Proteomes:UP000053268};
RN [1] {ECO:0000313|EMBL:KPI92672.1, ECO:0000313|Proteomes:UP000053268}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ya'a_city_454_Px {ECO:0000313|EMBL:KPI92672.1};
RC TISSUE=Whole body {ECO:0000313|EMBL:KPI92672.1};
RX PubMed=26354079; DOI=10.1038/ncomms9212;
RA Li X., Fan D., Zhang W., Liu G., Zhang L., Zhao L., Fang X., Chen L.,
RA Dong Y., Chen Y., Ding Y., Zhao R., Feng M., Zhu Y., Feng Y., Jiang X.,
RA Zhu D., Xiang H., Feng X., Li S., Wang J., Zhang G., Kronforst M.R.,
RA Wang W.;
RT "Outbred genome sequencing and CRISPR/Cas9 gene editing in butterflies.";
RL Nat. Commun. 6:8212-8212(2015).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the glutamate-gated ion channel (TC 1.A.10.1)
CC family. {ECO:0000256|ARBA:ARBA00008685}.
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DR EMBL; KQ459603; KPI92672.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A194PH89; -.
DR STRING; 66420.A0A194PH89; -.
DR Proteomes; UP000053268; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0015276; F:ligand-gated monoatomic ion channel activity; IEA:InterPro.
DR GO; GO:0050906; P:detection of stimulus involved in sensory perception; IEA:UniProt.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR InterPro; IPR015683; Ionotropic_Glu_rcpt.
DR InterPro; IPR001320; Iontro_rcpt_C.
DR PANTHER; PTHR18966; IONOTROPIC GLUTAMATE RECEPTOR; 1.
DR PANTHER; PTHR18966:SF494; IONOTROPIC RECEPTOR 64A-RELATED; 1.
DR Pfam; PF00060; Lig_chan; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Ion channel {ECO:0000256|ARBA:ARBA00023286};
KW Ion transport {ECO:0000256|ARBA:ARBA00023286};
KW Ligand-gated ion channel {ECO:0000256|ARBA:ARBA00023286};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000313|EMBL:KPI92672.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000053268};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 258..277
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 316..338
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 509..532
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 262..355
FT /note="Ionotropic glutamate receptor C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00060"
FT REGION 544..567
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 567 AA; 63173 MW; CA6B0C7240C950C4 CRC64;
MNEAWFDWLI AARTHDDYEH VHHILNETDI RFDANIVVAY PLHTKRLVHK DIGLCDKSFR
YNIKENGPTD KSKAKNNKRN GNKHLIYVKN SFENVHQRST RFKDLKRNST YQSGVWDRNR
SMSFVESPHP VEARKFVGEH LRFGSCNSTE EGGEAKDVDT TLFNDVLYFL TDRLNATTYM
QYYNKLGFQT YEGTWTGLLG ALMDNSIDIA LEPVTSHASR NQNMDFVFPL AETMFNIYIR
DQETTAVRDI FLAPFNPMLL ACVFAIGLVS TIAIYIINKF TPLVTNRSSM RFTEALVWST
GILCQQGGSS TPSNPAASIL LIVCLLFALV TYNSYAAFIT SVLSVRVASV DTVSAVLQSS
NLKIGYIRNG PDQMYLMSTK DVQLNAFYIR GYSEAENLVS SAEEGLFRAA KQDYAFFSEQ
RAARTTLRSL SQARGRCSLR ELAVPSTRAQ LAFPLSKGSP YARPILVSLL QLRGTGVMAR
LGTALVPAMP MCEPPPRFAS ARAADVRSAL VVFLVGLFGS IFIAKSALSL AVMNERWGKI
ERPKQHISGP RLAANPSVAP GTAGETP
//
