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Database: UniProt
Entry: A0A194PIY2_PAPXU
LinkDB: A0A194PIY2_PAPXU
Original site: A0A194PIY2_PAPXU 
ID   A0A194PIY2_PAPXU        Unreviewed;       640 AA.
AC   A0A194PIY2;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   31-JUL-2019, entry version 14.
DE   SubName: Full=G protein-activated inward rectifier potassium channel 4 {ECO:0000313|EMBL:KPI93008.1};
GN   ORFNames=RR46_14229 {ECO:0000313|EMBL:KPI93008.1};
OS   Papilio xuthus (Asian swallowtail butterfly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Holometabola; Lepidoptera; Glossata; Ditrysia;
OC   Papilionoidea; Papilionidae; Papilioninae; Papilio.
OX   NCBI_TaxID=66420 {ECO:0000313|EMBL:KPI93008.1, ECO:0000313|Proteomes:UP000053268};
RN   [1] {ECO:0000313|EMBL:KPI93008.1, ECO:0000313|Proteomes:UP000053268}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ya'a_city_454_Px {ECO:0000313|EMBL:KPI93008.1};
RC   TISSUE=Whole body {ECO:0000313|EMBL:KPI93008.1};
RX   PubMed=26354079; DOI=10.1038/ncomms9212;
RA   Li X., Fan D., Zhang W., Liu G., Zhang L., Zhao L., Fang X., Chen L.,
RA   Dong Y., Chen Y., Ding Y., Zhao R., Feng M., Zhu Y., Feng Y.,
RA   Jiang X., Zhu D., Xiang H., Feng X., Li S., Wang J., Zhang G.,
RA   Kronforst M.R., Wang W.;
RT   "Outbred genome sequencing and CRISPR/Cas9 gene editing in
RT   butterflies.";
RL   Nat. Commun. 6:8212-8212(2015).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU003822};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU003822}.
CC   -!- SIMILARITY: Belongs to the inward rectifier-type potassium channel
CC       (TC 1.A.2.1) family. {ECO:0000256|RuleBase:RU003822,
CC       ECO:0000256|SAAS:SAAS00549381}.
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DR   EMBL; KQ459603; KPI93008.1; -; Genomic_DNA.
DR   Proteomes; UP000053268; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005242; F:inward rectifier potassium channel activity; IEA:InterPro.
DR   GO; GO:0034765; P:regulation of ion transmembrane transport; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.1400; -; 1.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR041647; IRK_C.
DR   InterPro; IPR016449; K_chnl_inward-rec_Kir.
DR   InterPro; IPR013518; K_chnl_inward-rec_Kir_cyto.
DR   InterPro; IPR040445; Kir_TM.
DR   PANTHER; PTHR11767; PTHR11767; 1.
DR   Pfam; PF01007; IRK; 1.
DR   Pfam; PF17655; IRK_C; 1.
DR   PRINTS; PR01320; KIRCHANNEL.
DR   SUPFAM; SSF81296; SSF81296; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000053268};
KW   Ion channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434609, ECO:0000313|EMBL:KPI93008.1};
KW   Ion transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434639};
KW   Membrane {ECO:0000256|SAAS:SAAS00434581, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434575};
KW   Potassium transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434641};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053268};
KW   Transmembrane {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434543, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00036756,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00036755};
KW   Voltage-gated channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00048561}.
FT   TRANSMEM    236    259       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    318    342       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      202    347       IRK. {ECO:0000259|Pfam:PF01007}.
FT   DOMAIN      354    525       IRK_C. {ECO:0000259|Pfam:PF17655}.
FT   REGION      112    149       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION      601    640       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COMPBIAS    134    149       Polyampholyte. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
SQ   SEQUENCE   640 AA;  71785 MW;  EB188B4DDAD7B4E8 CRC64;
     MTTELSYEMQ ERDGEKEGKG KLATGKIFYK PGVIEEETDE TSAFESSMVE SPMLAPCGSS
     FLRPPQIHPS SSLHRIPTYS SSIGQSTIYR QDTCSASLGG RGVVIGTLSR DASGDTAGDA
     GADAAPRLSR AHAAHSAADM HADPESPACR EEAHLLPDEW LKVKTVPANG NLSPGVYYPT
     VSKRSRSHRH GATRRTRRRA ILKNGECNIL KSRISQRRLR FLQDMFTTLV DAQWRWTLLV
     FTLSFILSWL GFALIWWLIA FTHGDLEEDH LPPMQESSNW KPCVFNIYDF TSCFLFSIET
     QHTIGYGSRT TTEECPEAIF IMCLQSIVGV MIQAFMVGIV FAKMTRPKHR TQTLLFSKYA
     VVCQRDGELC LMFRVGDLRK SHIIGASVRA QLIRSRTTKE GELLSHYQTE LELNADGCDS
     NLFFIWPITM VHRINAESPF YGVSAADVLQ ERFEIVVILE GTIESTGQTT QARSSYTTSE
     IMWGHRFLPL VSYNRERQGY EVDYSKFDET SQVDTPLCSA KELDEFYGNQ PDRRSIESGE
     HLVLKMPERP TTEPKAEQKD GDFTEIIFDS GKGVPSSPLI NIADRLVVDA IRRASLTNRP
     SIVKYPPDYF NSLEDHSSSS SEDEKTKKKQ GSRKSSGKGV
//
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