ID   A0A194PYX6_PAPXU        Unreviewed;       716 AA.
AC   A0A194PYX6;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   SubName: Full=Transient-receptor-potential-like protein {ECO:0000313|EMBL:KPI98238.1};
GN   ORFNames=RR46_09454 {ECO:0000313|EMBL:KPI98238.1};
OS   Papilio xuthus (Asian swallowtail butterfly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Papilionoidea;
OC   Papilionidae; Papilioninae; Papilio.
OX   NCBI_TaxID=66420 {ECO:0000313|EMBL:KPI98238.1, ECO:0000313|Proteomes:UP000053268};
RN   [1] {ECO:0000313|EMBL:KPI98238.1, ECO:0000313|Proteomes:UP000053268}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ya'a_city_454_Px {ECO:0000313|EMBL:KPI98238.1};
RC   TISSUE=Whole body {ECO:0000313|EMBL:KPI98238.1};
RX   PubMed=26354079; DOI=10.1038/ncomms9212;
RA   Li X., Fan D., Zhang W., Liu G., Zhang L., Zhao L., Fang X., Chen L.,
RA   Dong Y., Chen Y., Ding Y., Zhao R., Feng M., Zhu Y., Feng Y., Jiang X.,
RA   Zhu D., Xiang H., Feng X., Li S., Wang J., Zhang G., Kronforst M.R.,
RA   Wang W.;
RT   "Outbred genome sequencing and CRISPR/Cas9 gene editing in butterflies.";
RL   Nat. Commun. 6:8212-8212(2015).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; KQ459585; KPI98238.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A194PYX6; -.
DR   STRING; 66420.A0A194PYX6; -.
DR   Proteomes; UP000053268; Unassembled WGS sequence.
DR   GO; GO:0034703; C:cation channel complex; IEA:UniProt.
DR   GO; GO:0005262; F:calcium channel activity; IEA:InterPro.
DR   Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR   InterPro; IPR002110; Ankyrin_rpt.
DR   InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR013555; TRP_dom.
DR   InterPro; IPR002153; TRPC_channel.
DR   NCBIfam; TIGR00870; trp; 1.
DR   PANTHER; PTHR10117; TRANSIENT RECEPTOR POTENTIAL CHANNEL; 1.
DR   PANTHER; PTHR10117:SF47; TRANSIENT-RECEPTOR-POTENTIAL-LIKE PROTEIN; 1.
DR   Pfam; PF00023; Ank; 1.
DR   Pfam; PF12796; Ank_2; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF08344; TRP_2; 1.
DR   SMART; SM00248; ANK; 2.
DR   SMART; SM01420; TRP_2; 1.
DR   SUPFAM; SSF48403; Ankyrin repeat; 1.
DR   PROSITE; PS50297; ANK_REP_REGION; 1.
DR   PROSITE; PS50088; ANK_REPEAT; 1.
PE   4: Predicted;
KW   ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW   ProRule:PRU00023}; Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Receptor {ECO:0000313|EMBL:KPI98238.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053268};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        396..414
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        426..447
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        609..632
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REPEAT          205..237
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   DOMAIN          240..302
FT                   /note="Transient receptor ion channel"
FT                   /evidence="ECO:0000259|SMART:SM01420"
SQ   SEQUENCE   716 AA;  82306 MW;  FF455CF1FB843ACA CRC64;
     MAIFLLEFQH WQYTCVSSFN KAIKSYIILK RGDPDSECTK QPMDLPVLPK SLTFEEKKYL
     LAVERGDMAN GDPDSECTKQ PMDLPVLPKS LTFEEKKYLL AVERGDMANV RRILQKAHRR
     NNVDMNCVDA LGRGALTLAI DGENLEMVEL LIVMGVDTKD ALLQAINAEF VEAVELLLEH
     EELIHKVGES YSWQKVDPNT AMFTRDITPL VLAAHKNNYE IIKLLLDRGA TLPDPHDIRC
     GCDDCIRDST EDSLRHSLAR LNEYRALASP SLIALSSTDP ILTAFELSWE LRNLAFAEQE
     SKAEYLELRR QVQKFAVDLL DQSRSSQELA IILNHDQDET PFNEGEHMKL ARLELAINFK
     QKKFVAHPNI QQLLASIWYD GVPGFRRKSA LEKIMIIFRV ALLFPFYCCL YMIAPNCETG
     KLMRKPFMKF LIHASSYLFF LLILILVSQR AEVQLIQVFG SEEMLKDLEK EMLKQRGNAP
     SFLEVLVFIY VLGFIWEETQ EIYVVGIRSY LRNMWNFIDF TRNSLYVAVA LLRIVAYIQQ
     TAEIERDPQT KFIPREHWDA YDPQLIAEGL FAAANIFSAL KLVHLFSINP HLGPLQISLG
     RMVIDIVKFF FIYTLVLFAF ACGLNQLLWY FAELEKQKCY VLPGGLPDWD NAGDSCMKWR
     SFGKIHINFN SICEGLNQLL WYFAELEKQK CYVLPGGLPD WDNAGDSCMK WRSFGK
//