ID A0A194Q5X7_PAPXU Unreviewed; 1202 AA.
AC A0A194Q5X7;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Myosin-XVIIIa {ECO:0000313|EMBL:KPI98810.1};
GN ORFNames=RR46_10128 {ECO:0000313|EMBL:KPI98810.1};
OS Papilio xuthus (Asian swallowtail butterfly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Papilionoidea;
OC Papilionidae; Papilioninae; Papilio.
OX NCBI_TaxID=66420 {ECO:0000313|EMBL:KPI98810.1, ECO:0000313|Proteomes:UP000053268};
RN [1] {ECO:0000313|EMBL:KPI98810.1, ECO:0000313|Proteomes:UP000053268}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ya'a_city_454_Px {ECO:0000313|EMBL:KPI98810.1};
RC TISSUE=Whole body {ECO:0000313|EMBL:KPI98810.1};
RX PubMed=26354079; DOI=10.1038/ncomms9212;
RA Li X., Fan D., Zhang W., Liu G., Zhang L., Zhao L., Fang X., Chen L.,
RA Dong Y., Chen Y., Ding Y., Zhao R., Feng M., Zhu Y., Feng Y., Jiang X.,
RA Zhu D., Xiang H., Feng X., Li S., Wang J., Zhang G., Kronforst M.R.,
RA Wang W.;
RT "Outbred genome sequencing and CRISPR/Cas9 gene editing in butterflies.";
RL Nat. Commun. 6:8212-8212(2015).
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|PROSITE-ProRule:PRU00782}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR EMBL; KQ459582; KPI98810.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A194Q5X7; -.
DR STRING; 66420.A0A194Q5X7; -.
DR Proteomes; UP000053268; Unassembled WGS sequence.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR CDD; cd01386; MYSc_Myo18; 1.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 6.20.240.20; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 2.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR036064; MYSc_Myo18.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR13140; MYOSIN; 1.
DR PANTHER; PTHR13140:SF709; UNCONVENTIONAL MYOSIN-XV; 1.
DR Pfam; PF00063; Myosin_head; 2.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM00242; MYSc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Reference proteome {ECO:0000313|Proteomes:UP000053268}.
FT DOMAIN 386..1184
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT REGION 44..64
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 96..129
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 189..266
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 762..787
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 214..241
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 764..784
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 480..487
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 1202 AA; 131297 MW; 118D466249A432E7 CRC64;
MFHIQGPFEQ SLRCGDDVSP SGNKTLATLA KIHKHCTGKA HAHGCLDNKH NPLTKSDSNT
SVQSKKSFRG DCFIEIKEAK SDNGFSRGNG SFTKSFSNST SSYDGHSDTD SESTSKTRPD
NKIAAPGERL FAQNTKASLM KTARMRYADD SVIATLTDEV DGEKWKQTFT RTPSRSSYRE
RKSGVVTIDE LKSDGLNDDD DNGDEKKKSQ LLNKSQFPRK GSFGNSSVNG NKQNNGSKPP
WRGASKNGKV TEPFVRSPSL RGSVKKKKVD GVPWRRLYEF SLWRRCGVNF ASVGAETERA
LLRPWKEMSS EESPPPFTAK SEEQLACEKE WLAAGHMWLA HRGGFTAVVR EGDGDTGRAK
VRVLHTGETL MVDEDDLEKA NPPQLERCED IASLRCLNEC GALHVLRSRY AAGLPHARAG
HALLVLGPPR RTAPIYTEKV AAMFRGCRAD DMPPHVFAAA QSAHRCMLAS RRDRAIVFLG
RSGSGKTSAM RHCVWYLASA YPAQGSKLTP DRLNAAFDVL HAFGSSRTSS NPHASRFVSL
TSLDFDGGGA LVSASVQTLL PDFRPGQSPL RALHTLFHGS DGRLRRELLL DQAPVNAPNP
FLTSTDKAEA PAEFSALKEA LHALSVTEPE QTVVWKILAA ICHLGWCGVT KANAGSGLKY
QFGSSGCASR AARLLGVGVD ELSRAVFAPP APTSPQTATA LSLLDSRLSW LDESELMMMN
IVLCAANAGS GLKYQFGSSG CASRAARLLG VGVDELSRAV FAPPAPTSPQ TATALRTPSP
SSDREVPGSE ALDAFVTGLY NETFNIVAAL VNRSLSTSAR TSASILLLDT PGADNPMCAG
QQNGAPLSKL LSNYLQERLQ AVFHDAMLVA PRERYAQEGI TLDDGTEEDW LSETVNPGPM
VELLDKSPQN SIVRSSQADL RDCDRRGLLW LLDEESMYPG SSDDSFLERA LTHYGPPHHT
HYLIKKAPHA RQFLLQHLQG TNPVLYDVTG WVKASRENPV TKKAHTLLQE SQNEDIGRLS
SWSRGACGVG AWSAAVGDAS TLRRASSIRR TLTSVDTLRR CGAGGVQFVC CLLTNQPTDA
NDDVNVPLLR SQFRGFQLLD AARLYKQGFP EHMPLSEFAR RYRLLATSES ETQENGQQTA
ALSDRQIVDD MLLALDLDVT SYRLGLTQVS HFDIWQVTCD SCATWPTRSQ VSVTLTFRNW
HW
//
