ID A0A194Q6V6_PAPXU Unreviewed; 376 AA.
AC A0A194Q6V6;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Tubulointerstitial nephritis antigen {ECO:0000313|EMBL:KPJ00735.1};
GN ORFNames=RR46_07574 {ECO:0000313|EMBL:KPJ00735.1};
OS Papilio xuthus (Asian swallowtail butterfly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Papilionoidea;
OC Papilionidae; Papilioninae; Papilio.
OX NCBI_TaxID=66420 {ECO:0000313|EMBL:KPJ00735.1, ECO:0000313|Proteomes:UP000053268};
RN [1] {ECO:0000313|EMBL:KPJ00735.1, ECO:0000313|Proteomes:UP000053268}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ya'a_city_454_Px {ECO:0000313|EMBL:KPJ00735.1};
RC TISSUE=Whole body {ECO:0000313|EMBL:KPJ00735.1};
RX PubMed=26354079; DOI=10.1038/ncomms9212;
RA Li X., Fan D., Zhang W., Liu G., Zhang L., Zhao L., Fang X., Chen L.,
RA Dong Y., Chen Y., Ding Y., Zhao R., Feng M., Zhu Y., Feng Y., Jiang X.,
RA Zhu D., Xiang H., Feng X., Li S., Wang J., Zhang G., Kronforst M.R.,
RA Wang W.;
RT "Outbred genome sequencing and CRISPR/Cas9 gene editing in butterflies.";
RL Nat. Commun. 6:8212-8212(2015).
CC -!- SIMILARITY: Belongs to the peptidase C1 family.
CC {ECO:0000256|ARBA:ARBA00008455}.
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DR EMBL; KQ459460; KPJ00735.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A194Q6V6; -.
DR Proteomes; UP000053268; Unassembled WGS sequence.
DR GO; GO:0008234; F:cysteine-type peptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR CDD; cd02620; Peptidase_C1A_CathepsinB; 1.
DR Gene3D; 3.90.70.10; Cysteine proteinases; 2.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR025661; Pept_asp_AS.
DR InterPro; IPR025660; Pept_his_AS.
DR InterPro; IPR013128; Peptidase_C1A.
DR InterPro; IPR000668; Peptidase_C1A_C.
DR PANTHER; PTHR12411; CYSTEINE PROTEASE FAMILY C1-RELATED; 1.
DR PANTHER; PTHR12411:SF834; SI:DKEY-158B13.1; 1.
DR Pfam; PF00112; Peptidase_C1; 2.
DR PRINTS; PR00705; PAPAIN.
DR SMART; SM00645; Pept_C1; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR PROSITE; PS00640; THIOL_PROTEASE_ASN; 1.
DR PROSITE; PS00639; THIOL_PROTEASE_HIS; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Reference proteome {ECO:0000313|Proteomes:UP000053268}.
FT DOMAIN 73..367
FT /note="Peptidase C1A papain C-terminal"
FT /evidence="ECO:0000259|SMART:SM00645"
SQ SEQUENCE 376 AA; 42779 MW; 1D7B9955BC75E1C8 CRC64;
MNTDWHCEDD PCLMSSSVVE GVNRGGSSWR AYNYPEFRNK KLKEGLIYKL GTFPLNAETR
RMGPLRYDKD VPYPTQFDAR TRWPGFISPI VDQGWCGSDW AVSLAGVASD RFAIQSNGAE
NMVLSPQTLL SCNVRAQQGC HGGHIDVAWN FARGHGLVDE KCFPYKASVT RCPFRPRGNL
IQDGCMPLVK RRTSRYKLGP PAKLSHEKDI MYDIMESGPV QVDEKCFPYK ASVTRCPFRP
RGNLIQDGCM PLVKRRTSRY KLGPPAKLSH EKDIMYDIME SGPVQAVMTV YQDFFHYRDG
VYRRSYHGNN ELKGFHSVRI IGWGEDRGDR YWVVANSWGR QWGENGYFRI ARGSNEADIE
SFVVTGLSDV TEANQK
//
