ID A0A194Q840_PAPXU Unreviewed; 561 AA.
AC A0A194Q840;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 22-FEB-2023, entry version 23.
DE SubName: Full=Rho GTPase-activating protein 21 {ECO:0000313|EMBL:KPJ01693.1};
GN ORFNames=RR46_05989 {ECO:0000313|EMBL:KPJ01693.1};
OS Papilio xuthus (Asian swallowtail butterfly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Papilionoidea;
OC Papilionidae; Papilioninae; Papilio.
OX NCBI_TaxID=66420 {ECO:0000313|EMBL:KPJ01693.1, ECO:0000313|Proteomes:UP000053268};
RN [1] {ECO:0000313|EMBL:KPJ01693.1, ECO:0000313|Proteomes:UP000053268}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ya'a_city_454_Px {ECO:0000313|EMBL:KPJ01693.1};
RC TISSUE=Whole body {ECO:0000313|EMBL:KPJ01693.1};
RX PubMed=26354079; DOI=10.1038/ncomms9212;
RA Li X., Fan D., Zhang W., Liu G., Zhang L., Zhao L., Fang X., Chen L.,
RA Dong Y., Chen Y., Ding Y., Zhao R., Feng M., Zhu Y., Feng Y., Jiang X.,
RA Zhu D., Xiang H., Feng X., Li S., Wang J., Zhang G., Kronforst M.R.,
RA Wang W.;
RT "Outbred genome sequencing and CRISPR/Cas9 gene editing in butterflies.";
RL Nat. Commun. 6:8212-8212(2015).
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DR EMBL; KQ459302; KPJ01693.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A194Q840; -.
DR STRING; 66420.A0A194Q840; -.
DR Proteomes; UP000053268; Unassembled WGS sequence.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR041681; PH_9.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR23175; PDZ DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR23175:SF23; PDZ DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF15410; PH_9; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000053268}.
FT DOMAIN 1..104
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 208..395
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 103..194
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 447..479
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 536..561
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 130..144
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 147..171
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 542..561
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 561 AA; 59495 MW; 50FFC130A4BEA737 CRC64;
MPSIDNDHET SSRSVLTAMD SGQAMTLWYT DILSPGGASG AVAAESGSRD ALDVRYSLAA
LADDYTKRKH VVRVTTAAGA ELLLQADGAA DAQRWLEALR RHSAEPPPAE PAPTAPASNN
TAEPAAAPAP APAGTQPDCP SPLPPQRSKK ITRNRSPTGM PANTNAAVVA QEQDVEGSHG
EAAAAHAGRG GGGCGAGGAP AVTGWLGAPL ERCPTDPDHP GVPLAVTLPA TAVEAYGLRT
VGVYRVPGNA GGVAALAAAL DRGCAPAGDP RWADVHVASS LLKAYLRRLP DPLLTHHLYP
AFIAADRSPE RGRELRRLVQ ALPAAHYATL RYLVQHLRRV AAHSAANKME PRNLAIVFGP
TLVRAASDDM LAMVNDMSSQ CRIIESFLMH YSWYFEENAG EPPAELQGGD APQPSRDLLI
HNVKKIEGKD VSTRDIVSSI ISAANRKIQR KPRTKAAAAD KKWAGSDKSP PSSPPHHATA
LAHYDGLHHS HHSHHSTDKI EIESSGARHT LNTFSIDARP ITRGQVVCAP LRSLRCPGPL
HVHGRKQAHR SHRTNASRRG R
//
