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Database: UniProt
Entry: A0A194QEQ6_PAPXU
LinkDB: A0A194QEQ6_PAPXU
Original site: A0A194QEQ6_PAPXU 
ID   A0A194QEQ6_PAPXU        Unreviewed;       581 AA.
AC   A0A194QEQ6;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   31-JUL-2019, entry version 14.
DE   SubName: Full=Inward rectifier potassium channel irk-1 {ECO:0000313|EMBL:KPJ03904.1};
GN   ORFNames=RR46_01856 {ECO:0000313|EMBL:KPJ03904.1};
OS   Papilio xuthus (Asian swallowtail butterfly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Holometabola; Lepidoptera; Glossata; Ditrysia;
OC   Papilionoidea; Papilionidae; Papilioninae; Papilio.
OX   NCBI_TaxID=66420 {ECO:0000313|EMBL:KPJ03904.1, ECO:0000313|Proteomes:UP000053268};
RN   [1] {ECO:0000313|EMBL:KPJ03904.1, ECO:0000313|Proteomes:UP000053268}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ya'a_city_454_Px {ECO:0000313|EMBL:KPJ03904.1};
RC   TISSUE=Whole body {ECO:0000313|EMBL:KPJ03904.1};
RX   PubMed=26354079; DOI=10.1038/ncomms9212;
RA   Li X., Fan D., Zhang W., Liu G., Zhang L., Zhao L., Fang X., Chen L.,
RA   Dong Y., Chen Y., Ding Y., Zhao R., Feng M., Zhu Y., Feng Y.,
RA   Jiang X., Zhu D., Xiang H., Feng X., Li S., Wang J., Zhang G.,
RA   Kronforst M.R., Wang W.;
RT   "Outbred genome sequencing and CRISPR/Cas9 gene editing in
RT   butterflies.";
RL   Nat. Commun. 6:8212-8212(2015).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU003822};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU003822}.
CC   -!- SIMILARITY: Belongs to the inward rectifier-type potassium channel
CC       (TC 1.A.2.1) family. {ECO:0000256|RuleBase:RU003822,
CC       ECO:0000256|SAAS:SAAS00549381}.
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DR   EMBL; KQ459054; KPJ03904.1; -; Genomic_DNA.
DR   Proteomes; UP000053268; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005242; F:inward rectifier potassium channel activity; IEA:InterPro.
DR   GO; GO:0034765; P:regulation of ion transmembrane transport; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.1400; -; 1.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR041647; IRK_C.
DR   InterPro; IPR016449; K_chnl_inward-rec_Kir.
DR   InterPro; IPR013518; K_chnl_inward-rec_Kir_cyto.
DR   InterPro; IPR040445; Kir_TM.
DR   PANTHER; PTHR11767; PTHR11767; 1.
DR   Pfam; PF01007; IRK; 1.
DR   Pfam; PF17655; IRK_C; 1.
DR   PRINTS; PR01320; KIRCHANNEL.
DR   SUPFAM; SSF81296; SSF81296; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000053268};
KW   Ion channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434609, ECO:0000313|EMBL:KPJ03904.1};
KW   Ion transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434639};
KW   Membrane {ECO:0000256|SAAS:SAAS00434581, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434575};
KW   Potassium transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434641};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053268};
KW   Transmembrane {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434543, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00036756,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00036755};
KW   Voltage-gated channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00048561}.
FT   TRANSMEM    230    253       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    303    326       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      194    332       IRK. {ECO:0000259|Pfam:PF01007}.
FT   DOMAIN      340    505       IRK_C. {ECO:0000259|Pfam:PF17655}.
FT   REGION      112    131       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION      161    188       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COMPBIAS    169    188       Basic. {ECO:0000256|SAM:MobiDB-lite}.
SQ   SEQUENCE   581 AA;  65705 MW;  AB133CD0725C14B3 CRC64;
     MEFDNERRGS RTRALERSLS YSAAIGNGSG RSSIEIPAMV NTEVYTNEEI KKHYRISQTY
     VEGKEITFPN VITNVDSNSS QPYIDSKISE ISQYSSEDET TDNGLTMTID VETESQSPKS
     SETRHISDAS TQPMVSSIVT NETYDRIDFI ESIYNDPDDL AGGHGYSTPY SKRRKKRKKR
     RHQHGRPIRS RRVVYKSGEE NVPVRTNIPA KSIKYMRDIV NTVINSKWRF IILLMIVAHF
     IFWFIFAGIW YAVASSYQDD IGDGKEHCVT GTSSFAGLLM MSVETQMTIG YGVRYPSEEC
     PEAIIVMVIE IVAGTALSGG LSSLLFTKLV RPNRHLSSVG FSKKATVCLR DGELCLQFRV
     WDLLNLHLIG STITAYMLKP IRTLEGEIVH NYIHPLRLKQ ARALLLWPVT VAHVIDSRSP
     LYDLSAQDMM DYRFEIVVCL TGSSKNMGTV TQSRTSYLSK EIIWGYRFKN VLKYSKKEES
     YVIDVDNLNT VEQVETPLCS ASRLKLFEDD IKSSHNLLTP TNMSLSPTNM SLSQESSTVS
     KIGESVPSSP VFTRTGTQRS FGWNFRKFYP EENKNGVEFS S
//
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