ID A0A194QQG4_PAPMA Unreviewed; 652 AA.
AC A0A194QQG4;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE SubName: Full=Sodium-dependent neutral amino acid transporter SLC6A17 {ECO:0000313|EMBL:KPJ07748.1};
GN ORFNames=RR48_11304 {ECO:0000313|EMBL:KPJ07748.1};
OS Papilio machaon (Old World swallowtail butterfly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Papilionoidea;
OC Papilionidae; Papilioninae; Papilio.
OX NCBI_TaxID=76193 {ECO:0000313|EMBL:KPJ07748.1, ECO:0000313|Proteomes:UP000053240};
RN [1] {ECO:0000313|EMBL:KPJ07748.1, ECO:0000313|Proteomes:UP000053240}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ya'a_city_454_Pm {ECO:0000313|EMBL:KPJ07748.1};
RC TISSUE=Whole body {ECO:0000313|EMBL:KPJ07748.1};
RX PubMed=26354079; DOI=10.1038/ncomms9212;
RA Li X., Fan D., Zhang W., Liu G., Zhang L., Zhao L., Fang X., Chen L.,
RA Dong Y., Chen Y., Ding Y., Zhao R., Feng M., Zhu Y., Feng Y., Jiang X.,
RA Zhu D., Xiang H., Feng X., Li S., Wang J., Zhang G., Kronforst M.R.,
RA Wang W.;
RT "Outbred genome sequencing and CRISPR/Cas9 gene editing in butterflies.";
RL Nat. Commun. 6:8212-8212(2015).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the sodium:neurotransmitter symporter (SNF) (TC
CC 2.A.22) family. {ECO:0000256|ARBA:ARBA00006459}.
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DR EMBL; KQ461181; KPJ07748.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A194QQG4; -.
DR InParanoid; A0A194QQG4; -.
DR Proteomes; UP000053240; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR InterPro; IPR000175; Na/ntran_symport.
DR InterPro; IPR037272; SNS_sf.
DR PANTHER; PTHR11616; SODIUM/CHLORIDE DEPENDENT TRANSPORTER; 1.
DR PANTHER; PTHR11616:SF182; TRANSPORTER; 1.
DR Pfam; PF00209; SNF; 2.
DR PRINTS; PR00176; NANEUSMPORT.
DR SUPFAM; SSF161070; SNF-like; 2.
DR PROSITE; PS50267; NA_NEUROTRAN_SYMP_3; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000053240};
KW Symport {ECO:0000256|ARBA:ARBA00022847};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 199..220
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 226..250
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 271..296
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 308..331
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 417..438
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 458..477
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 489..510
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 537..557
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 594..633
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 603..619
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 652 AA; 71882 MW; C1D0FBE9BC1D6948 CRC64;
MAAKAEPIGP RNGHELAPLN TRADGSERPH GVTIVLQGSR GSLQREAPGE DRAAWSGKLQ
FFLSIIGYSV GLGNIWRFPY LCQQNGGERK KPQTTLTIML VPGTRVKETS KQQLKIAVIG
CIPDPVPDYA GAGKLRIESQ YRVVIPKVLS ADQLPWAHCP QDNSSAELEC SKASATVYYW
YREALDASPS IEDPGVPRWW IVLYLLLAWI IVFFIVMKGI QSSGKVVYFT SLFPYAVLTI
FFIRGITLPG SADGIIHMYK PKLGKLLDPT VWLDAATQVF YSFGLAFGSL IAFGSYNPPN
NNCVRDVLLV SVCNALTAIY ASVVIFSILG FKAFTMVEKC MTKEIKVLAM HQIGGFTLNS
TFDYYKEEFP TLNNTVVTAL NLTGCTMSRQ LEEAAEGTGL AFIVFTQAIL KLTPAPFWSI
IFFLMLLSLG LGSQIGIMEG MLCTIFDIDF FKRMSKPVIT GAVCTFCFLV GLIFTTGAGE
YWLKMFDSFA GTIGLVVVAL LEMISVVYIY GHEKFTNDIY EMTGYRPGWY WQVTWRYVGP
FIVTCILLSS LVFMLIIPPT YGAWNAAEVI SPETAPPAPA QLVAEASTRF TIGDFDSSDS
EPGEVNTGDH FEDSSSSDEE ILNTKPTSTG IRLAMKPIGH KPTTFKMDVV DD
//
