ID A0A194QZQ0_PAPMA Unreviewed; 1830 AA.
AC A0A194QZQ0;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
GN ORFNames=RR48_10203 {ECO:0000313|EMBL:KPJ11023.1};
OS Papilio machaon (Old World swallowtail butterfly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Papilionoidea;
OC Papilionidae; Papilioninae; Papilio.
OX NCBI_TaxID=76193 {ECO:0000313|EMBL:KPJ11023.1, ECO:0000313|Proteomes:UP000053240};
RN [1] {ECO:0000313|EMBL:KPJ11023.1, ECO:0000313|Proteomes:UP000053240}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ya'a_city_454_Pm {ECO:0000313|EMBL:KPJ11023.1};
RC TISSUE=Whole body {ECO:0000313|EMBL:KPJ11023.1};
RX PubMed=26354079; DOI=10.1038/ncomms9212;
RA Li X., Fan D., Zhang W., Liu G., Zhang L., Zhao L., Fang X., Chen L.,
RA Dong Y., Chen Y., Ding Y., Zhao R., Feng M., Zhu Y., Feng Y., Jiang X.,
RA Zhu D., Xiang H., Feng X., Li S., Wang J., Zhang G., Kronforst M.R.,
RA Wang W.;
RT "Outbred genome sequencing and CRISPR/Cas9 gene editing in butterflies.";
RL Nat. Commun. 6:8212-8212(2015).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC Evidence={ECO:0000256|ARBA:ARBA00001556};
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DR EMBL; KQ460890; KPJ11023.1; -; Genomic_DNA.
DR STRING; 76193.A0A194QZQ0; -.
DR InParanoid; A0A194QZQ0; -.
DR Proteomes; UP000053240; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0051321; P:meiotic cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0031047; P:regulatory ncRNA-mediated gene silencing; IEA:UniProtKB-KW.
DR GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
DR CDD; cd20435; Tudor_TDRD12_rpt2; 1.
DR Gene3D; 2.30.30.140; -; 2.
DR Gene3D; 2.40.50.90; -; 1.
DR Gene3D; 2.60.40.790; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR007052; CS_dom.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR008978; HSP20-like_chaperone.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR035437; SNase_OB-fold_sf.
DR InterPro; IPR002999; Tudor.
DR PANTHER; PTHR22655:SF2; ATP-DEPENDENT RNA HELICASE TDRD12-RELATED; 1.
DR PANTHER; PTHR22655; UNCHARACTERIZED; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00567; TUDOR; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00333; TUDOR; 2.
DR SUPFAM; SSF49764; HSP20-like chaperones; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 2.
DR PROSITE; PS51203; CS; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS50304; TUDOR; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW Differentiation {ECO:0000256|ARBA:ARBA00022782};
KW Helicase {ECO:0000313|EMBL:KPJ11023.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Meiosis {ECO:0000256|ARBA:ARBA00023254};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000053240};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-mediated gene silencing {ECO:0000256|ARBA:ARBA00023158};
KW Spermatogenesis {ECO:0000256|ARBA:ARBA00022871}.
FT DOMAIN 633..776
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 1359..1418
FT /note="Tudor"
FT /evidence="ECO:0000259|PROSITE:PS50304"
FT DOMAIN 1680..1766
FT /note="CS"
FT /evidence="ECO:0000259|PROSITE:PS51203"
FT REGION 439..460
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 495..522
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1621..1640
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1811..1830
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 507..522
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1830 AA; 209715 MW; 5B99F977B3273F51 CRC64;
MPPDSYLVEV LHYLNPHLIW IEVIDPSVAR GDKFVFEQIG IYGVLPVELT LDVEEEDLKT
RVSDEWLPAA SVTIKKALAE AKEVKFCPTY IDRRSSIFDD NIHKYGELLV KKRDKKWKPL
SKILIKAGIA IYDMCLFHQQ LGLGKLNTRL KSSESEAVIQ DIENYYLKKN VSKKNWKKSV
EEKTVVSHAT LELESALTTM NLQKHNDVMQ QLLQNKLNDF ELCKDIDEEP LGKGFKGKQQ
NVARETKAKE ALNSNLENNL KATTLKKKLE LMTKKSNSQK MDNGFKNNPK QILENTKKFL
ELNATKNLER KLNQEISCKN NKDQTNEMKS YYNGQTFIKG TKNITGLKLP KPISKEYPAN
EKRVCYGPPG ILPTKLSVKV LVENVEPPLD SSTCVDNQEK TVEKEDIFAN IDSGLNVEIT
NKNSLMSIKQ NVEIHQKYTD PARFNRREST SSKGKDSLHL TDRTDSEITV KSSSKVLQKK
LMLYERKKTN FLDSSFTSCS ETSNKDSSSL EDVKVRKKEN KKEIRDSDDE EVVRKINEEY
SIPNVSKELK CQNTNTDNNI SMKNSVNPFK NIDPTISIFV EKLVTPVLMV HTKMNKRIEP
VFNLRDVNFN ANIQMALKTM SIESPMMLQT ISWFCILRGY STFMISPVGS GKTMGYLPAV
CRLVSDIDSD DIESVGPKSI IICATAKSVG QVEKMSKMFL NVNNKVVTCF AGVDDALITT
SLLNGCDILI CTPSYLVRLL QVTDFGVDLR RLATVVLDDC ERLGEVYINE LKYIMLRIKE
TLKNRANKEL RVQYVVASRI WCDFMEPIVK KAPYSVVCIG AFQECVLYSK TGMSVSFVYD
NTKMQAVHDF LTQIDVTKRI VIICDTDDEI FLLKNALRKY KNPVFTCDSS MTIQDLYNLR
ITWDEYEEPL LGPILLCCND TLAHMNVTDA YYLLIYSLPP LFSTFCRWFS VLNDKYPSIF
KSDNDIVKIK ILIEEKNVEQ LPKMLNFIRR CTDNTFPQHL NVICKNIMVE KDKAKASKLV
PLCNNLLGLG YCPDYWNCHF RHSFVEDVDN MKEWMPLTGQ VTFKILHYHS AVCYSARLLS
NTVKDSTKKY PQTYSTLSLK MGMYYSKESN KKPHGIPKIG DICAVSLKQN FFARCQVIKI
LSTYQRGNPN SVLIKLLDEE KIETTRDIYL YYIPEELKKI ETHVVQVRLA NIQPKDKDVT
YSDLARDQLK RITDKDEELY MRGEVAMSIG NCVFVDTLEA CQDLASINQT VVKHDFKSDL
LEKHAVPNME HLDKIKKLCD DKFEVKVKTQ TRKSLESTKP KTIGSWAHLD KDNMSLVFFG
CALSPSKFFV RLQKFESCLN MLLKEIQKFV AENPKPLSHV EEGDIVLAMF PDDETFERAR
IDSIIDNNKV KCFFVDQGDW REVSTKKIIA MKEEFISKLP FQAIECRLLG VTPAGEEWTD
FATNWFSNIC FDVDTDNMKS LYVKCFTKEK AEFTGGNKYG IVMIDTNSDD DIVINQVLID
VNLAKENESE MKYLDKCETI NVSKNSSKSD QLSDSEVEEV EDNESFPMCK TGNVKANNMS
TLDTIFKQPI RSVPLVGSDD SDDSDRWHIN MAEDFFKLFK PNTNDSKIKD VKNLSAIMNG
TEKDVNTSDD KPENSLPKLS QIQNNTKELD SDDYTSPESS DVLNTPDKRV IKSLLVTDNM
RKPKVIWRQN KKFVFIKVNL IGLQMYDVKI EGRAISFAAN LNDVDYAFDI ELYGAIDVVK
SQHWNKGQYI LMKLHKILNK NWLTLTKDGE IRKWIVYDVE SIDVSSDEDI IEEHSKKAML
SAIQNIYNKQ ETESEDDDFD DDLNYGYTKK
//
