ID A0A194R9G1_PAPMA Unreviewed; 1726 AA.
AC A0A194R9G1;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Receptor-type tyrosine-protein phosphatase beta {ECO:0000313|EMBL:KPJ14478.1};
GN ORFNames=RR48_13549 {ECO:0000313|EMBL:KPJ14478.1};
OS Papilio machaon (Old World swallowtail butterfly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Papilionoidea;
OC Papilionidae; Papilioninae; Papilio.
OX NCBI_TaxID=76193 {ECO:0000313|EMBL:KPJ14478.1, ECO:0000313|Proteomes:UP000053240};
RN [1] {ECO:0000313|EMBL:KPJ14478.1, ECO:0000313|Proteomes:UP000053240}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ya'a_city_454_Pm {ECO:0000313|EMBL:KPJ14478.1};
RC TISSUE=Whole body {ECO:0000313|EMBL:KPJ14478.1};
RX PubMed=26354079; DOI=10.1038/ncomms9212;
RA Li X., Fan D., Zhang W., Liu G., Zhang L., Zhao L., Fang X., Chen L.,
RA Dong Y., Chen Y., Ding Y., Zhao R., Feng M., Zhu Y., Feng Y., Jiang X.,
RA Zhu D., Xiang H., Feng X., Li S., Wang J., Zhang G., Kronforst M.R.,
RA Wang W.;
RT "Outbred genome sequencing and CRISPR/Cas9 gene editing in butterflies.";
RL Nat. Commun. 6:8212-8212(2015).
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DR EMBL; KQ460473; KPJ14478.1; -; Genomic_DNA.
DR RefSeq; XP_014359321.1; XM_014503835.1.
DR STRING; 76193.A0A194R9G1; -.
DR GeneID; 106711511; -.
DR InParanoid; A0A194R9G1; -.
DR OrthoDB; 3061575at2759; -.
DR Proteomes; UP000053240; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.
DR GO; GO:0009653; P:anatomical structure morphogenesis; IEA:UniProt.
DR GO; GO:0016043; P:cellular component organization; IEA:UniProt.
DR GO; GO:0016311; P:dephosphorylation; IEA:InterPro.
DR GO; GO:0048666; P:neuron development; IEA:UniProt.
DR CDD; cd00047; PTPc; 1.
DR Gene3D; 3.90.190.10; Protein tyrosine phosphatase superfamily; 1.
DR InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR InterPro; IPR000242; PTP_cat.
DR InterPro; IPR003595; Tyr_Pase_cat.
DR InterPro; IPR000387; Tyr_Pase_dom.
DR PANTHER; PTHR45706; TYROSINE-PROTEIN PHOSPHATASE; 1.
DR PANTHER; PTHR45706:SF4; TYROSINE-PROTEIN PHOSPHATASE; 1.
DR Pfam; PF00102; Y_phosphatase; 2.
DR PRINTS; PR00700; PRTYPHPHTASE.
DR SMART; SM00194; PTPc; 1.
DR SMART; SM00404; PTPc_motif; 1.
DR SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 1.
DR PROSITE; PS50056; TYR_PHOSPHATASE_2; 1.
DR PROSITE; PS50055; TYR_PHOSPHATASE_PTP; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius}; Receptor {ECO:0000313|EMBL:KPJ14478.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000053240};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..26
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 27..1726
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5008265020"
FT TRANSMEM 1301..1323
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1418..1714
FT /note="Tyrosine-protein phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS50055"
FT DOMAIN 1631..1705
FT /note="Tyrosine specific protein phosphatases"
FT /evidence="ECO:0000259|PROSITE:PS50056"
FT REGION 49..169
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 600..635
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 693..794
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 983..1012
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1051..1146
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1175..1204
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1216..1264
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 66..96
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 97..129
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 719..794
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 986..1012
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1216..1245
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1246..1260
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1726 AA; 191005 MW; 6E62DA02A0EB3362 CRC64;
MESPVRICIG AAIVVNLLLI CTLVNGGPLS HEASSTTIKD EKTTKYSRMN STWTTKNQPK
TPDVALNELH PKESTSEEHT EKNAKYKDRG RVKFQSHLKS TSESPLRRIK SSTEPTKYVS
STTETMKSAK IANDIGKPRD KKSSEVSSST TSSTTSEEEE ITESDDMQEM NDSQLAEADE
DNIFDRYTSS KFQDSFNLPG YNDDDSYKDK MYSQTKHEFS NFDKVLKHFS KNMFDSSEND
NVHGDPYNSH SYFDFEADLT TPRNDYFDQK YADISSSIMN NLASVKTKSP EMNSTTPQDI
ITENIGFEKL SNGSPNNKSM MIIKNTKEIR RLDNDQAGTA NRELSDIHGT SIYYEMSVLS
TETYNINHSD DYDCDNDTLP AETTMSTSLQ EEDQSLTAVQ PVMATASSMP VTITAIPAIV
LPNVIPNSLN TIIPIQDSNI PISSQNYVSN TERTVKVSPR NRNYSKRLNL TGNKVSPNSV
TPQTIPTMNS GWRPVTHKFY FTTPKIKPIW IAPRRNISKV YKTSYPTTIY AEHFNIKDKY
STTPRPMAPQ KTILTTLPSD IDPVLQSDVS GVEKFVQSQI ITDNTIPTLS KRGSMKFTTS
VPLSANNTEH KDPTNIIGTS KEGASSSISL TNSSKEIETV DEAGTTASVS SASQTQFVNK
ISSTDKNTPS KISTVKTITP NLSVSLDEAS TIDKTGEMDL TDPLSATTNS ESDSTEEKDY
LNQTGTIGNS SATSNESLDQ TESVSQSNSK NISETPFGKT NKVREGSPPG STESVGTASV
EDTDNTSQTS SEWVTSVGGM SINDLEIPPT MTAWALASLR TPPTMSIKVL NGSQSTQKTV
DENELQKVSE PLDQKETTTV STTPTTTPVA ALSNYVLKNI TEIDQNKLPW KPIISIEVRD
EKEPVTKSER LPAESNISVQ SSLKPENTTK RTQTEEKIAM TTETIKINDA RPSWIPAMIN
ETTTEETDEN EDEIQPVDVK KSTGFESITK LPSGVTTPTD ENDTSTEQSE VRTTTDYDIT
TIRFSYVPTE QMTETEVPII NKTWHKIIPT RTNKPTTPIT TYRPTFSTTT EETEETTTMI
VDTTPQLESS SINDNATNQS HEGIGQTTTE EITTNNPTTT YPTTSNPTTA NPTTTNPTTD
STTECDETTT MTTAASMMQR TDPEEMPQIA TTTEPPIQTK NESISEENSD SNEVIQDTTK
PPTTTTIITT TTITTTTEKG PETTVVPSTT EQTTPGYSET TIKPNENIPF HHEEDTTTES
SEMTTKSINE LEDLTSYTDD MTTEASSRVF TNEETSSGAT IAIVVTTIGV TALILLVVLL
LVVRRRGRRG VYAQRCTPVS LDAYSLDSVS VGHRKGNHRL CSKRSYGNPA YDDEVTSHPM
QYAALANFAL DVESISAEFA EIPSVSVPPE AVPPGCEDKN RYSNVLPLPE TRVPLTRLGN
DPTTEYMNAN YVTGPGNIRN YYILCQAPLA NTVADFWRMI WEQNSRLIVM LTEYMENGVE
KCYEYLPPSE VSDNKRCFGD FQVVLKKREQ RDKYAISTLQ LIHMGTRTWR EVTHLWYFWP
AKGVPDDYDS VIDFISEMRS YMKISQTAKE YDEEGVEVIY GDDTKSSLET LSKLRSEGRA
SGRGPHVYSP ARAEEMMRSN NGTLRSQGVR PCVCVCASGA GRSAAMVALE TCARALSAGA
VDVPRVVRRL RAQRPHALAN RHHYIFIYKV LSEYGNKLMG SGVDNI
//
