ID A0A194RB51_PAPMA Unreviewed; 1928 AA.
AC A0A194RB51;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Dynein heavy chain 10, axonemal {ECO:0000313|EMBL:KPJ14719.1};
GN ORFNames=RR48_06893 {ECO:0000313|EMBL:KPJ14719.1};
OS Papilio machaon (Old World swallowtail butterfly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Papilionoidea;
OC Papilionidae; Papilioninae; Papilio.
OX NCBI_TaxID=76193 {ECO:0000313|EMBL:KPJ14719.1, ECO:0000313|Proteomes:UP000053240};
RN [1] {ECO:0000313|EMBL:KPJ14719.1, ECO:0000313|Proteomes:UP000053240}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ya'a_city_454_Pm {ECO:0000313|EMBL:KPJ14719.1};
RC TISSUE=Whole body {ECO:0000313|EMBL:KPJ14719.1};
RX PubMed=26354079; DOI=10.1038/ncomms9212;
RA Li X., Fan D., Zhang W., Liu G., Zhang L., Zhao L., Fang X., Chen L.,
RA Dong Y., Chen Y., Ding Y., Zhao R., Feng M., Zhu Y., Feng Y., Jiang X.,
RA Zhu D., Xiang H., Feng X., Li S., Wang J., Zhang G., Kronforst M.R.,
RA Wang W.;
RT "Outbred genome sequencing and CRISPR/Cas9 gene editing in butterflies.";
RL Nat. Commun. 6:8212-8212(2015).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KQ460436; KPJ14719.1; -; Genomic_DNA.
DR STRING; 76193.A0A194RB51; -.
DR InParanoid; A0A194RB51; -.
DR Proteomes; UP000053240; Unassembled WGS sequence.
DR GO; GO:0030286; C:dynein complex; IEA:InterPro.
DR GO; GO:0008569; F:minus-end-directed microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR Gene3D; 1.10.8.1220; -; 1.
DR Gene3D; 1.20.1270.280; -; 1.
DR Gene3D; 1.20.920.20; -; 2.
DR Gene3D; 1.20.920.30; -; 1.
DR Gene3D; 3.10.490.20; -; 1.
DR Gene3D; 6.10.140.1060; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 4.
DR Gene3D; 1.10.8.720; Region D6 of dynein motor; 1.
DR InterPro; IPR035706; AAA_9.
DR InterPro; IPR041658; AAA_lid_11.
DR InterPro; IPR042219; AAA_lid_11_sf.
DR InterPro; IPR041228; Dynein_C.
DR InterPro; IPR043160; Dynein_C_barrel.
DR InterPro; IPR024743; Dynein_HC_stalk.
DR InterPro; IPR024317; Dynein_heavy_chain_D4_dom.
DR InterPro; IPR004273; Dynein_heavy_D6_P-loop.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR22878:SF63; DYNEIN AXONEMAL HEAVY CHAIN 10; 1.
DR PANTHER; PTHR22878; UNCHARACTERIZED; 1.
DR Pfam; PF12780; AAA_8; 2.
DR Pfam; PF12781; AAA_9; 1.
DR Pfam; PF18198; AAA_lid_11; 1.
DR Pfam; PF18199; Dynein_C; 1.
DR Pfam; PF03028; Dynein_heavy; 1.
DR Pfam; PF12777; MT; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000053240}.
FT DOMAIN 84..214
FT /note="Dynein heavy chain AAA module D4"
FT /evidence="ECO:0000259|Pfam:PF12780"
FT DOMAIN 226..394
FT /note="Dynein heavy chain AAA module D4"
FT /evidence="ECO:0000259|Pfam:PF12780"
FT DOMAIN 407..526
FT /note="Dynein heavy chain coiled coil stalk"
FT /evidence="ECO:0000259|Pfam:PF12777"
FT DOMAIN 548..821
FT /note="Dynein heavy chain coiled coil stalk"
FT /evidence="ECO:0000259|Pfam:PF12777"
FT DOMAIN 849..1069
FT /note="Dynein heavy chain ATP-binding dynein motor region"
FT /evidence="ECO:0000259|Pfam:PF12781"
FT DOMAIN 1320..1432
FT /note="Dynein heavy chain region D6 P-loop"
FT /evidence="ECO:0000259|Pfam:PF03028"
FT DOMAIN 1463..1606
FT /note="Dynein heavy chain AAA lid"
FT /evidence="ECO:0000259|Pfam:PF18198"
FT DOMAIN 1613..1925
FT /note="Dynein heavy chain C-terminal"
FT /evidence="ECO:0000259|Pfam:PF18199"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 409..436
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 703..751
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1052..1079
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1928 AA; 218832 MW; 55761BD9DE2DB86E CRC64;
MSEKPAKSDA VPEETEVMEE EQEEQEHMLT LEEYVLRDPM LFGDYRNALD EEEIRYYEDL
LDYEAVYFLF QEILDEYSER VGKMSVVLFE DCLEHLTRTH RVLRMERGHV MLVGVGGSGK
KSICRLAAFA AGCDVFEIVI TRSYNENTFK DDMKRLYNQL GVDGKPTVFL FTAAQILEEG
FLEFINNILM IGMIPALFGD DEKDAIINAL RNESLLSSSS QRHNFRILEE GFLEFINNIL
MIGMIPALFG DDEKDAIINA LRNESNDAGY GVGKDAVWNY FCSKCLQNLH VVLSMSPSGD
VLRNRCRSFP GLVNNTTIDW QFPWPKQALL AVANVFLADV QKIPDEFRGI IVEHVVHVHL
SVAVYSAEFL ARLRRNNYVT PKHYMDFLTS YIALLGEKDA FIVAQCERLK GGLLKIEEAN
IQLEDLNAKL AVQKVIVAEQ THECEILLKE ISTATEAAVG KQQVAAEKSA EISQQSEVIA
EEKAEAEEAL SAALPALEAA RLALADLDKN DITEIRSFAT PPEAVQCYYF SDPSPTEAAV
GKQQVAAEKS AEISQQSEVI AEEKAEAEEA LSAALPALEA ARLALADLDK NDITEIRSFA
TPPEAVQVVC ECVVIIRGIK DVSWKGAKGM MADPNFLRNL QEMNCDLITQ AQVKAVKAHM
KKSKKLDTMQ QISKAGYGLL KFVIAVLGYC AVYKEVKPKK DKVEALEKEY TEAVNYLASL
NREIDRLQRT LDGLNQRYDT AMLRRQELQE ETDIMMRRLV AADKLMSGLS SEQKRWTEDL
KALHVEQSRL IGNCLLAASF LSYAGPFSFS FRQTMIYEDW LGDVKERGIP LTEPFTIEKN
LTNEVEISGW NSEGLPPDEL SVQNGILTTR ASRFPLCIDP QTQALTWIKR KEAKNNLKVL
SFNDPQFVRH LEMAIKYGIP VLFQDVNEYI DPVVDNVLEK NIKVEGGRTF VLLGSSEVDY
DPNFRLYLTT KLANPQFNPA AYAKAVVINY TVTVQGLEDQ LLSVVVRAER SDLEEQRESL
IMETSANKSL LSGLEDSLLR ELATSTGNML DNVELVDTLE NTKAKAAEVM EKLELAEVTT
KDIEKLRDGY RPVAKRGSIL FFVLSDMAVV NSMYQYSLSS YLEVFSFSLR KAMPNVILAK
RLKNIIDMLT KNVYDYGCTG IFERHKLLYS FQMNIKLEQN EGNVSQAQLD FFIKGNVALE
KAATVCPATW IPSQGWQDIM KLSTDFSEVF AMLPDQIRTK LEDWREWFDS DTPETNEIPN
GYRERLKPFE LLMLLRCFRV DRIYLALTDY ITATLGEEYI TPPLDHYCDS LDMIFEQTTP
FTPVVFILSP GSDPTADLMK LADRCGFGGG KFKYLSLGQG QEGAALALLE GAISHGQWLI
LQNCHLLVSF LRELEKQLEL LTKPHPEYRL WLTTDPTPTF PIGILQRSLK VVTEPPNGLK
LNLRNTYFKM RPHALEECAH PQFKKLVYVL AFFHAVVQER RKYDKIGWNI SYDFSESDFV
VCMQILQCYL DRTTGVVPWA TLKYLFGEVM YGGRVIDDFD RRVVGTYMDE YLGEFLFDKF
QPFHFYHDDV FDYYIPPDGE REEYIEFVDS LPLANTPEVF GLHPNAEIGY FSQAVRDMWS
HLIELQPQTS EGGGAMSRED FIDSIAVDVL AKLPAQYEVW RVRKQFEMNI TPAVVVLLQE
LERFNRLISK MHSTLSLLRK ALAGEIGMDA VLDNVASSLF NGQLPNVWRA LAPATCKGLG
GWMDHFMERT KQYTDWASIP PPPQTHTRAL LATMEEPIVM WLSGLHVPES YLIAHVQTTC
RARVWPLDRS TQYTRVTKYT AVPDIEQRPD SGCYVRGLYL EGARWDLEDG CLRRSHPKVL
VTELPFMHII PIEAHKVKLQ NTLRTPVYTT SQRRNAMGVG LVFESDLWTA EHISHWVLQG
VCLIMNTD
//
