ID A0A194RK28_PAPMA Unreviewed; 786 AA.
AC A0A194RK28;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Titin {ECO:0000313|EMBL:KPJ17690.1};
GN ORFNames=RR48_07174 {ECO:0000313|EMBL:KPJ17690.1};
OS Papilio machaon (Old World swallowtail butterfly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Papilionoidea;
OC Papilionidae; Papilioninae; Papilio.
OX NCBI_TaxID=76193 {ECO:0000313|EMBL:KPJ17690.1, ECO:0000313|Proteomes:UP000053240};
RN [1] {ECO:0000313|EMBL:KPJ17690.1, ECO:0000313|Proteomes:UP000053240}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ya'a_city_454_Pm {ECO:0000313|EMBL:KPJ17690.1};
RC TISSUE=Whole body {ECO:0000313|EMBL:KPJ17690.1};
RX PubMed=26354079; DOI=10.1038/ncomms9212;
RA Li X., Fan D., Zhang W., Liu G., Zhang L., Zhao L., Fang X., Chen L.,
RA Dong Y., Chen Y., Ding Y., Zhao R., Feng M., Zhu Y., Feng Y., Jiang X.,
RA Zhu D., Xiang H., Feng X., Li S., Wang J., Zhang G., Kronforst M.R.,
RA Wang W.;
RT "Outbred genome sequencing and CRISPR/Cas9 gene editing in butterflies.";
RL Nat. Commun. 6:8212-8212(2015).
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DR EMBL; KQ460118; KPJ17690.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A194RK28; -.
DR STRING; 76193.A0A194RK28; -.
DR InParanoid; A0A194RK28; -.
DR Proteomes; UP000053240; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0009653; P:anatomical structure morphogenesis; IEA:UniProt.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProt.
DR Gene3D; 2.60.40.10; Immunoglobulins; 5.
DR InterPro; IPR013162; CD80_C2-set.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR23278:SF19; OBSCURIN; 1.
DR PANTHER; PTHR23278; SIDESTEP PROTEIN; 1.
DR Pfam; PF08205; C2-set_2; 1.
DR Pfam; PF07679; I-set; 1.
DR Pfam; PF13927; Ig_3; 1.
DR SMART; SM00409; IG; 4.
DR SMART; SM00408; IGc2; 4.
DR SUPFAM; SSF49265; Fibronectin type III; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 5.
DR PROSITE; PS50853; FN3; 1.
DR PROSITE; PS50835; IG_LIKE; 5.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000053240};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 595..618
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..82
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 90..185
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 192..285
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 290..382
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 387..475
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 485..580
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 644..719
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 668..685
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 698..712
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 786 AA; 86635 MW; 5EFA4A2E20240DF2 CRC64;
MVLWFKESDG EPLYSYDIRG RSYTQPKLWS SPTVFGNRAF FRGGATPAVL MIDNVAAVDA
GVYRCRVDFK NSPTRNLKVN FSVIIPPSRP TIYDAKRRDR TKLVEPYNEG SNVLLICEVE
GGVPRPRVTW YLENVVIDDS YEQRSDGITI NTLTFPNVGR QHLNARLVCQ ASNTNLAPPE
TKVLILDINL KPITVTILTK EKQVSADKRY EVECKTTGSR PEATVTWWKN NRQLKRMAKN
FSENNETLSV LSLVPAVEDD GRQLTCRAEN KHIPDSAIED KWRLNVHYVP IVDLKMGSNL
NPNEIKEGDD VYFECTVKAN PKTHRLVWFH DNSEIFHNEA LGVILSAQSL VLQSLTRRAA
GDYACMAANS EGKGTSNPVT LQIRYAPVCA ERKDNELYGA LKHETVSLHC AVDANPALVS
FHWTFNNSGE QTDLPPRLYN SHGNMSTLNY TPTSDMEYGT LACYGENSVG QQKVPCLFQL
VIAGRPLQLQ NCSVANQSVD ALYVECVESF DGGLPQTFLL ELLELPSLKV RYNVTTSRSP
PSWEVRGLPA GARYRLDLYA VNAKGRSDVT TIETVTLRGQ AKYTGESNAL GMSPVLASVA
AMSALLASAV CGALAVLYRR HVARHRHLPA KHAPLSEAMY GERAGQCPTP VKSEPALASP
GEARGPLLRS PDSREADDAD PDIIPSLYER RPVSNGYMSL QRPPTASKPS NPGEESEPDA
AGFYADLRKK DYKIPLTSSY HSLGRAHKGG VACGAGAGAT VTSSLTAHRL RPEVVTTSHR
VQESCI
//
