ID A0A194RSJ2_PAPMA Unreviewed; 626 AA.
AC A0A194RSJ2;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE RecName: Full=Transporter {ECO:0000256|RuleBase:RU003732};
GN ORFNames=RR48_12547 {ECO:0000313|EMBL:KPJ19036.1};
OS Papilio machaon (Old World swallowtail butterfly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Papilionoidea;
OC Papilionidae; Papilioninae; Papilio.
OX NCBI_TaxID=76193 {ECO:0000313|EMBL:KPJ19036.1, ECO:0000313|Proteomes:UP000053240};
RN [1] {ECO:0000313|EMBL:KPJ19036.1, ECO:0000313|Proteomes:UP000053240}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ya'a_city_454_Pm {ECO:0000313|EMBL:KPJ19036.1};
RC TISSUE=Whole body {ECO:0000313|EMBL:KPJ19036.1};
RX PubMed=26354079; DOI=10.1038/ncomms9212;
RA Li X., Fan D., Zhang W., Liu G., Zhang L., Zhao L., Fang X., Chen L.,
RA Dong Y., Chen Y., Ding Y., Zhao R., Feng M., Zhu Y., Feng Y., Jiang X.,
RA Zhu D., Xiang H., Feng X., Li S., Wang J., Zhang G., Kronforst M.R.,
RA Wang W.;
RT "Outbred genome sequencing and CRISPR/Cas9 gene editing in butterflies.";
RL Nat. Commun. 6:8212-8212(2015).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the sodium:neurotransmitter symporter (SNF) (TC
CC 2.A.22) family. {ECO:0000256|ARBA:ARBA00006459,
CC ECO:0000256|RuleBase:RU003732}.
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DR EMBL; KQ459984; KPJ19036.1; -; Genomic_DNA.
DR RefSeq; XP_014370832.1; XM_014515346.1.
DR AlphaFoldDB; A0A194RSJ2; -.
DR KEGG; pmac:106720628; -.
DR InParanoid; A0A194RSJ2; -.
DR OrthoDB; 3084493at2759; -.
DR Proteomes; UP000053240; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR InterPro; IPR000175; Na/ntran_symport.
DR InterPro; IPR037272; SNS_sf.
DR PANTHER; PTHR11616:SF311; SODIUM-DEPENDENT DOPAMINE TRANSPORTER; 1.
DR PANTHER; PTHR11616; SODIUM/CHLORIDE DEPENDENT TRANSPORTER; 1.
DR Pfam; PF00209; SNF; 1.
DR PRINTS; PR00176; NANEUSMPORT.
DR SUPFAM; SSF161070; SNF-like; 1.
DR PROSITE; PS00610; NA_NEUROTRAN_SYMP_1; 1.
DR PROSITE; PS00754; NA_NEUROTRAN_SYMP_2; 1.
DR PROSITE; PS50267; NA_NEUROTRAN_SYMP_3; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000053240};
KW Symport {ECO:0000256|ARBA:ARBA00022847, ECO:0000256|RuleBase:RU003732};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU003732};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU003732}.
FT TRANSMEM 20..39
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 51..73
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 94..122
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 200..218
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 230..250
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 283..300
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 312..337
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 357..381
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 412..437
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 443..466
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 487..506
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 526..546
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 626 AA; 68830 MW; 7676640D83AA5134 CRC64;
MALKTPTPRD GERETWGKKV DFLLSVIGFA VDLANVWRFP YLCYKNGGGA FLVPYCIMLV
VGGIPLFYME LALGQFHRKG AITCWGRLVP LFKGIGYAVV LIAFYVDFYY NVIIAWALRF
FFASFTTMLP WTSCNNEWNT PFCQPFEANW DALPVNKSEP LHNESDSMAS SQPFTSAASE
YFNRAILELQ GSEGLHDLGA IKWDMALCLL AVYIICYFSL WKGISTSGKV VWFTALFPYA
VLLILLVRGI TLPGSATGIQ YYLSPNFEAI TQPQVWVDAA TQVFFSLGPG FGVLLAYASY
NKYHNNVYKD AILTSVINSC TSFVAGFVIF SVLGYMAHAS GKQVQDVATE GPGLVFVVYP
AAIATMPGST FWALIFFMML LTLGLDSSFG GSEAIITALS DEFPPIGRHR EIFVACLFTL
YFFVGLASCT KGGFYFFQLL DRYAAGYSML VAVFFEAIAV SWIYGTERFC EDIRDMIGFR
PGVYWRVCWR FAAPAFLLFI TVYGLLDYQP LAYEGYVYPG WANALGWTIA GSSVICIPTV
AVYKILTTKG TFLERLRILT TPLADTERGS VHNGVVVSES GGVRLTSNAG TPTTPTAPAA
DTNTTIVANS IATTTNVSLA PGPALV
//
