ID A0A194SBE5_RHOGW Unreviewed; 536 AA.
AC A0A194SBE5;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 22-FEB-2023, entry version 21.
DE RecName: Full=Acetyl-CoA hydrolase {ECO:0000256|ARBA:ARBA00017958};
DE EC=3.1.2.1 {ECO:0000256|ARBA:ARBA00011920};
DE AltName: Full=Acetyl-CoA deacylase {ECO:0000256|ARBA:ARBA00029672};
GN ORFNames=RHOBADRAFT_34165 {ECO:0000313|EMBL:KPV76731.1};
OS Rhodotorula graminis (strain WP1).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina;
OC Microbotryomycetes; Sporidiobolales; Sporidiobolaceae; Rhodotorula.
OX NCBI_TaxID=578459 {ECO:0000313|EMBL:KPV76731.1, ECO:0000313|Proteomes:UP000053890};
RN [1] {ECO:0000313|EMBL:KPV76731.1, ECO:0000313|Proteomes:UP000053890}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WP1 {ECO:0000313|EMBL:KPV76731.1,
RC ECO:0000313|Proteomes:UP000053890};
RX PubMed=26441909; DOI=10.3389/fmicb.2015.00978;
RA Firrincieli A., Otillar R., Salamov A., Schmutz J., Khan Z., Redman R.S.,
RA Fleck N.D., Lindquist E., Grigoriev I.V., Doty S.L.;
RT "Genome sequence of the plant growth promoting endophytic yeast Rhodotorula
RT graminis WP1.";
RL Front. Microbiol. 6:978-978(2015).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=acetyl-CoA + H2O = acetate + CoA + H(+); Xref=Rhea:RHEA:20289,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30089,
CC ChEBI:CHEBI:57287, ChEBI:CHEBI:57288; EC=3.1.2.1;
CC Evidence={ECO:0000256|ARBA:ARBA00001831};
CC -!- SIMILARITY: Belongs to the acetyl-CoA hydrolase/transferase family.
CC {ECO:0000256|ARBA:ARBA00009632}.
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DR EMBL; KQ474075; KPV76731.1; -; Genomic_DNA.
DR RefSeq; XP_018272780.1; XM_018413176.1.
DR AlphaFoldDB; A0A194SBE5; -.
DR STRING; 578459.A0A194SBE5; -.
DR GeneID; 28973625; -.
DR OMA; DEALSWH; -.
DR OrthoDB; 100792at2759; -.
DR Proteomes; UP000053890; Unassembled WGS sequence.
DR GO; GO:0008775; F:acetate CoA-transferase activity; IEA:InterPro.
DR GO; GO:0003986; F:acetyl-CoA hydrolase activity; IEA:UniProtKB-EC.
DR GO; GO:0006083; P:acetate metabolic process; IEA:InterPro.
DR Gene3D; 3.30.750.70; 4-hydroxybutyrate coenzyme like domains; 1.
DR Gene3D; 3.40.1080.20; Acetyl-CoA hydrolase/transferase C-terminal domain; 1.
DR Gene3D; 3.40.1080.10; Glutaconate Coenzyme A-transferase; 1.
DR InterPro; IPR026888; AcetylCoA_hyd_C.
DR InterPro; IPR038460; AcetylCoA_hyd_C_sf.
DR InterPro; IPR046433; ActCoA_hydro.
DR InterPro; IPR003702; ActCoA_hydro_N.
DR InterPro; IPR037171; NagB/RpiA_transferase-like.
DR PANTHER; PTHR43609; ACETYL-COA HYDROLASE; 1.
DR PANTHER; PTHR43609:SF1; ACETYL-COA HYDROLASE; 1.
DR Pfam; PF13336; AcetylCoA_hyd_C; 1.
DR Pfam; PF02550; AcetylCoA_hydro; 1.
DR SUPFAM; SSF100950; NagB/RpiA/CoA transferase-like; 2.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000053890}.
FT DOMAIN 22..243
FT /note="Acetyl-CoA hydrolase/transferase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02550"
FT DOMAIN 346..494
FT /note="Acetyl-CoA hydrolase/transferase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13336"
SQ SEQUENCE 536 AA; 59308 MW; F289BDD0F282F067 CRC64;
MLPSRVCRSV QPSAALRSRV ARQSYLNKLA RPQDLVSHFK NGDYIGWSGF TGVGYPKETP
AALAEHVEKN NLQGDLRFSL FVGASTGPEI EERWARNKMI SRRFPHQVGK SIAKAINHGE
IEFADTHLSM FAQNLTYGFY SLDKKGGDKT KPLDWAIVEA TEILSDGSIV PGASVGATPE
ILASADKIII EVNTALPSFK GLHDINPIAA PPYRLPFLIT HCADRIGTPS IQIDPERVVA
IVESNKPDNT GQNAPETEDS KKLAGHLIQF LEDEVAAGRM PKNLHPIQSG IGNVANSIIT
GLAQSKFEHL NVWTEVLQDA FIPLLDTGKL DFATATSIRL SPEMFKTFYE NWDRYFDKLL
LRPQQTANSP EIIRRLGVIA LNTPLEIDIF SHANSTNALG SRMLNGLGGS ADFLRNAKLS
VMHTPSARPS KTDPTGISCI VPFASHIDQT EHDLDVIVTE QGLADLRGLS PRQRAPLIIS
KCAHPDYKDQ LMDYYERALH ECLAKGSAHM PHMLRNAFKM HINFEEHGTM KLDKWD
//
