ID A0A194SDH0_RHOGW Unreviewed; 824 AA.
AC A0A194SDH0;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN ORFNames=RHOBADRAFT_49210 {ECO:0000313|EMBL:KPV78642.1};
OS Rhodotorula graminis (strain WP1).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina;
OC Microbotryomycetes; Sporidiobolales; Sporidiobolaceae; Rhodotorula.
OX NCBI_TaxID=578459 {ECO:0000313|EMBL:KPV78642.1, ECO:0000313|Proteomes:UP000053890};
RN [1] {ECO:0000313|EMBL:KPV78642.1, ECO:0000313|Proteomes:UP000053890}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WP1 {ECO:0000313|EMBL:KPV78642.1,
RC ECO:0000313|Proteomes:UP000053890};
RX PubMed=26441909; DOI=10.3389/fmicb.2015.00978;
RA Firrincieli A., Otillar R., Salamov A., Schmutz J., Khan Z., Redman R.S.,
RA Fleck N.D., Lindquist E., Grigoriev I.V., Doty S.L.;
RT "Genome sequence of the plant growth promoting endophytic yeast Rhodotorula
RT graminis WP1.";
RL Front. Microbiol. 6:978-978(2015).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-
CC [protein]; Xref=Rhea:RHEA:17989, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC COMP:11604, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:83421, ChEBI:CHEBI:456216; EC=2.7.11.1;
CC Evidence={ECO:0000256|ARBA:ARBA00001433};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-
CC threonyl-[protein]; Xref=Rhea:RHEA:46608, Rhea:RHEA-COMP:11060,
CC Rhea:RHEA-COMP:11605, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216;
CC EC=2.7.11.1; Evidence={ECO:0000256|ARBA:ARBA00000775};
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DR EMBL; KQ474073; KPV78642.1; -; Genomic_DNA.
DR RefSeq; XP_018274691.1; XM_018415232.1.
DR AlphaFoldDB; A0A194SDH0; -.
DR STRING; 578459.A0A194SDH0; -.
DR GeneID; 28975680; -.
DR OMA; THTINRT; -.
DR OrthoDB; 5491350at2759; -.
DR Proteomes; UP000053890; Unassembled WGS sequence.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR024604; GSG2_C.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR PANTHER; PTHR24419; INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE; 1.
DR PANTHER; PTHR24419:SF18; SERINE_THREONINE-PROTEIN KINASE HASPIN; 1.
DR Pfam; PF12330; Haspin_kinase; 1.
DR SMART; SM01331; DUF3635; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Reference proteome {ECO:0000313|Proteomes:UP000053890};
KW Serine/threonine-protein kinase {ECO:0000256|ARBA:ARBA00022527};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 594..691
FT /note="Serine/threonine-protein kinase haspin C-terminal"
FT /evidence="ECO:0000259|SMART:SM01331"
FT REGION 1..230
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 652..751
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..16
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 41..55
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 95..135
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 159..173
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 213..230
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 652..666
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 824 AA; 86534 MW; 9384706FCEBDC325 CRC64;
MPPTALSGST QHYRAYGKRK TNVINRRQPL GAWNASPVAA PAADGTTSSS DDSETTTDDS
SSDDDDEPRV TLATRTEAAP CRRKPAKQPA FAVVVESRRS SSTRPPPGAR TTASTSASKE
NGPAAVWTSS VSGKVQGKAV ELVKGGATSG DEAARRSPLG GASSSSSSRR RPAQSGKKAV
YGARRARATV VLSSGSSSEE EERLPTPPGV RRTPVVVQSS GSATSSPLTS LQATPQAVVV
LSDEESEGED ELVDDRAALV LEDEASSLSV AESSDANDLV VVDSASSRAA PRSAGRFPPQ
LASLRSSLLS PNLFSFSSFV ASPPAPFSAT RPATAAPWRK IGEASYSEVF ATTDDAGRDM
VVKIIPVAAP SRSRTGTRGG SALRSDVPLP FVSSCDAVRR EIEVSGVLGG REGGIDGFVR
FRGAFLVQGS YPDELLSAWD DFKRAQGPAC DEQVRPDVLP ETQLFALLLL DNAGSALETF
KLKSWVEAAG VLGQVVEALG KAEEECGFEH RDLHWGNILL QSVAARRAPA SSLSHRLASL
SLGQPSSPAL SPLALLDPTS CGVRATLIDF TLSRCCVSTS ADADQVVFDP FEDDDLFEGE
GEYQFEVYRR MRALVERAQG EQGDKAWRAS EPRTNVLWLH YLVDKLLHSS RLRLPPPPPP
SPSSATPSSP HRQSGPAASP RRAPLAHRPV TRRTSTAFAP SLSSPARARA RASVGGGVGR
PAAFGSPLKP RARTLPTPTT ASARAAAATE ARERAAHDAL VRAERALEAA VEGWGLGSGT
GTGGRGAAKG RGRARKVVKV PAGRDAGLAF ASAGEFARWW FGGF
//
