ID   A0A194V6L8_9PEZI        Unreviewed;       709 AA.
AC   A0A194V6L8;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=Acetoacetyl-CoA synthetase {ECO:0000313|EMBL:KUI59533.1};
GN   ORFNames=VP1G_06797 {ECO:0000313|EMBL:KUI59533.1};
OS   Valsa mali var. pyri (nom. inval.).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Diaporthales; Valsaceae; Valsa.
OX   NCBI_TaxID=694573 {ECO:0000313|EMBL:KUI59533.1, ECO:0000313|Proteomes:UP000078576};
RN   [1] {ECO:0000313|Proteomes:UP000078576}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SXYL134 {ECO:0000313|Proteomes:UP000078576};
RA   Yin Z., Liu H., Gao X., Li Z., Song N., Ke X., Dai Q., Wu Y., Sun Y.,
RA   Xu J.-R., Kang Z.K., Wang L., Huang L.;
RT   "Genome Sequence of Valsa Canker Pathogens Uncovers a Specific Adaption of
RT   Colonization on Woody Bark.";
RL   Submitted (DEC-2014) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KN714732; KUI59533.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A194V6L8; -.
DR   STRING; 694573.A0A194V6L8; -.
DR   OrthoDB; 45466at2759; -.
DR   Proteomes; UP000078576; Unassembled WGS sequence.
DR   GO; GO:0030729; F:acetoacetate-CoA ligase activity; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR   Gene3D; 3.30.300.30; -; 1.
DR   Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR   InterPro; IPR005914; Acac_CoA_synth.
DR   InterPro; IPR032387; ACAS_N.
DR   InterPro; IPR045851; AMP-bd_C_sf.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR   InterPro; IPR042099; ANL_N_sf.
DR   NCBIfam; TIGR01217; ac_ac_CoA_syn; 1.
DR   PANTHER; PTHR42921; ACETOACETYL-COA SYNTHETASE; 1.
DR   PANTHER; PTHR42921:SF1; ACETOACETYL-COA SYNTHETASE; 1.
DR   Pfam; PF16177; ACAS_N; 1.
DR   Pfam; PF00501; AMP-binding; 1.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR   PROSITE; PS00455; AMP_BINDING; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Ligase {ECO:0000256|ARBA:ARBA00022598};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000078576}.
FT   DOMAIN          47..104
FT                   /note="Acetyl-coenzyme A synthetase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF16177"
FT   DOMAIN          119..485
FT                   /note="AMP-dependent synthetase/ligase"
FT                   /evidence="ECO:0000259|Pfam:PF00501"
SQ   SEQUENCE   709 AA;  77715 MW;  3AEEA176D1DBCF04 CRC64;
     MPSSSHTAID PEEGAPILWR HPNPADTQLA HFMRHVSHKY GLELEAYPKL YQWSIDHIAD
     FWAEVWDFCG IANSRRYDTV LPEGSSMFPR PDFFSGARLN FAENLLYPAD VDVDDNDVAV
     ITVTEKEPGA AVETTWAALR GAVRRCADAL RAAGVKQNDV VAGFVSNHVQ ALVAMLAAAS
     MGAVWTGISP DNGVFAVLDR LAQIGPKVLF ADNGVVYNGK EWPSTSKTME IVEELRRKGL
     ETVIVIRNLP DAGLGIEELR SKVDRVEEYE SFLNSSPSDE PLHFEQLPPS HPLYILYSSG
     TTGLPKAIIH TAAGTLIQHK KEHFLHCSIT SRSRMLYYTT TSWMMWHWSI SALAVGASLV
     LYSGSPFKPR GYMSLPRLLS ELKVTHFGTS AAYLISLEAN NIRPVDDPSL DLSRLEAIYS
     TASPLPPSTF SFVYEAFPKT INLGSITGGT DIISLFGAPC PLLPVRAGEI QCAGLGMAIK
     VVDSASPADD PRPVDPSYAP GDLVCVEPFP CQPLTFFGPG GDEKYRSAYF ERFTGNNIWH
     HGDFVVLTKS GGLIMKGRSD GILKPAGVRF GSAEIYNILT KFFAAEVEDA VCVGRRRPDV
     DKDETVCLFV VMKRKKSNKD DDDDDGPSPF VRGVTDRRIR DVIRAQLSPR HVPAVVEECG
     PAGVPKTGNG KKIEVAVKQI LSGMEVRTNA SVANPEALEW FRAWAEGHP
//