ID A0A194VF20_9PEZI Unreviewed; 730 AA.
AC A0A194VF20;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=NADH-ubiquinone oxidoreductase 78 kDa subunit, mitochondrial {ECO:0008006|Google:ProtNLM};
GN ORFNames=VP1G_09504 {ECO:0000313|EMBL:KUI62371.1};
OS Valsa mali var. pyri (nom. inval.).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Diaporthales; Valsaceae; Valsa.
OX NCBI_TaxID=694573 {ECO:0000313|EMBL:KUI62371.1, ECO:0000313|Proteomes:UP000078576};
RN [1] {ECO:0000313|Proteomes:UP000078576}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SXYL134 {ECO:0000313|Proteomes:UP000078576};
RA Yin Z., Liu H., Gao X., Li Z., Song N., Ke X., Dai Q., Wu Y., Sun Y.,
RA Xu J.-R., Kang Z.K., Wang L., Huang L.;
RT "Genome Sequence of Valsa Canker Pathogens Uncovers a Specific Adaption of
RT Colonization on Woody Bark.";
RL Submitted (DEC-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[2Fe-2S] cluster; Xref=ChEBI:CHEBI:190135;
CC Evidence={ECO:0000256|ARBA:ARBA00034078};
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- SIMILARITY: Belongs to the complex I 75 kDa subunit family.
CC {ECO:0000256|ARBA:ARBA00005404}.
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DR EMBL; KN714810; KUI62371.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A194VF20; -.
DR STRING; 694573.A0A194VF20; -.
DR OrthoDB; 19999at2759; -.
DR Proteomes; UP000078576; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0005739; C:mitochondrion; IEA:UniProt.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro.
DR GO; GO:0042773; P:ATP synthesis coupled electron transport; IEA:InterPro.
DR CDD; cd00207; fer2; 1.
DR CDD; cd02773; MopB_Res-Cmplx1_Nad11; 1.
DR Gene3D; 3.10.20.740; -; 1.
DR Gene3D; 3.30.200.210; -; 1.
DR Gene3D; 3.30.70.20; -; 1.
DR Gene3D; 3.40.50.740; -; 1.
DR InterPro; IPR036010; 2Fe-2S_ferredoxin-like_sf.
DR InterPro; IPR001041; 2Fe-2S_ferredoxin-type.
DR InterPro; IPR006656; Mopterin_OxRdtase.
DR InterPro; IPR006963; Mopterin_OxRdtase_4Fe-4S_dom.
DR InterPro; IPR000283; NADH_UbQ_OxRdtase_75kDa_su_CS.
DR InterPro; IPR010228; NADH_UbQ_OxRdtase_Gsu.
DR InterPro; IPR019574; NADH_UbQ_OxRdtase_Gsu_4Fe4S-bd.
DR InterPro; IPR015405; NDUFS1-like_C.
DR NCBIfam; TIGR01973; NuoG; 1.
DR PANTHER; PTHR43105:SF13; NADH-UBIQUINONE OXIDOREDUCTASE 75 KDA SUBUNIT, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43105; RESPIRATORY NITRATE REDUCTASE; 1.
DR Pfam; PF13510; Fer2_4; 1.
DR Pfam; PF00384; Molybdopterin; 1.
DR Pfam; PF10588; NADH-G_4Fe-4S_3; 1.
DR Pfam; PF09326; NADH_dhqG_C; 1.
DR SMART; SM00929; NADH-G_4Fe-4S_3; 1.
DR SUPFAM; SSF54292; 2Fe-2S ferredoxin-like; 1.
DR SUPFAM; SSF54862; 4Fe-4S ferredoxins; 1.
DR SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
DR PROSITE; PS51839; 4FE4S_HC3; 1.
DR PROSITE; PS51669; 4FE4S_MOW_BIS_MGD; 1.
DR PROSITE; PS00642; COMPLEX1_75K_2; 1.
DR PROSITE; PS00643; COMPLEX1_75K_3; 1.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022485};
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Reference proteome {ECO:0000313|Proteomes:UP000078576};
KW Translocase {ECO:0000256|ARBA:ARBA00022967}.
FT DOMAIN 98..137
FT /note="4Fe-4S His(Cys)3-ligated-type"
FT /evidence="ECO:0000259|PROSITE:PS51839"
FT DOMAIN 237..293
FT /note="4Fe-4S Mo/W bis-MGD-type"
FT /evidence="ECO:0000259|PROSITE:PS51669"
FT REGION 710..730
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 730 AA; 79616 MW; 20F0C483DCE9B01D CRC64;
MLRQTLARSA WRNGRRPVSN SARAFTATAR RPAEIELTIA GSALIQACEK AGATVPRKLM
IAGNCRMCLV EVERAPKPVA SCAWPVSPGM VVKTNSPLAH KAREGVMEFL LANHPLDCPI
CDQGGECDLQ DQSMRYGADR GRFHEIGGKR GVEDKNIGPL IKTSMNRCIH CTRCIRFAND
IAGAPELGST GRGNDIQIGT YLEKNLDTEL SGNVVDLCPV GALTSKPYAF RARPWELKKT
ESVDVLDGLG SNIRIDARGL EVMRIIPRLN DDINEEWIND KTRFACDGLK TQRLTLPLIR
REGKFEAADW EQALTEIAQG WEKKAPKGNE FKVVAGELTD VETLVTMKDL ANKLGSENLA
LDMPAGNQPI AHGVDVRSNY LFNSRIWGIE EADTILIVGS NPRHEAAVLN ARIRKHWMRS
DLEIGVVGET WDSTFEFEHL GTDLNALKTA LAGSFGKKLS AAQRPMIIVG SAVTDHADAK
AFYETIGSFV DKHAANFLTE EWNGYNVLQR AASRAGAYEV GFITPSVEVA ETTPKFIWLL
GADEINEADI PKDAFVVYQG HHGDKGAQIA DVVLPGAAYT EKNATYVNTE GRVQMTRAAT
GLPGAARTDW KIIRAVSEFL GAPLPYDDVA AVRDRMVEIS PALAAYDVVE PVALQQLSKV
QLVEQNKGAK ATGAPLKLPI ENFYFTDVIS RSSPTMARCS AAKATGDPRT NFMAPGMEED
KPLGQVSYGA
//
