ID   A0A194VR91_9PEZI        Unreviewed;      1228 AA.
AC   A0A194VR91;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   13-SEP-2023, entry version 19.
DE   RecName: Full=MMS19 nucleotide excision repair protein {ECO:0000256|RuleBase:RU367072};
GN   ORFNames=VM1G_01336 {ECO:0000313|EMBL:KUI66512.1};
OS   Valsa mali.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Diaporthales; Valsaceae; Valsa.
OX   NCBI_TaxID=105487 {ECO:0000313|EMBL:KUI66512.1};
RN   [1] {ECO:0000313|EMBL:KUI66512.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=03-8 {ECO:0000313|EMBL:KUI66512.1};
RA   Yin Z., Liu H., Gao X., Li Z., Song N., Ke X., Dai Q., Wu Y., Sun Y.,
RA   Xu J.-R., Kang Z.K., Wang L., Huang L.;
RT   "Genome Sequence of Valsa Canker Pathogens Uncovers a Specific Adaption of
RT   Colonization on Woody Bark.";
RL   Submitted (DEC-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Key component of the cytosolic iron-sulfur protein assembly
CC       (CIA) complex, a multiprotein complex that mediates the incorporation
CC       of iron-sulfur cluster into apoproteins specifically involved in DNA
CC       metabolism and genomic integrity. In the CIA complex, MMS19 acts as an
CC       adapter between early-acting CIA components and a subset of cellular
CC       target iron-sulfur proteins. {ECO:0000256|RuleBase:RU367072}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU367072}.
CC   -!- SIMILARITY: Belongs to the MET18/MMS19 family.
CC       {ECO:0000256|RuleBase:RU367072}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CM003099; KUI66512.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A194VR91; -.
DR   OrthoDB; 38995at2759; -.
DR   Proteomes; UP000078559; Chromosome 2.
DR   GO; GO:0097361; C:CIA complex; IEA:UniProtKB-UniRule.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-UniRule.
DR   GO; GO:0016226; P:iron-sulfur cluster assembly; IEA:UniProtKB-UniRule.
DR   GO; GO:0097428; P:protein maturation by iron-sulfur cluster transfer; IEA:UniProtKB-UniRule.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR039920; MET18/MMS19.
DR   InterPro; IPR029240; MMS19_N.
DR   PANTHER; PTHR12891; DNA REPAIR/TRANSCRIPTION PROTEIN MET18/MMS19; 1.
DR   PANTHER; PTHR12891:SF0; MMS19 NUCLEOTIDE EXCISION REPAIR PROTEIN HOMOLOG; 1.
DR   Pfam; PF14500; MMS19_N; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
PE   3: Inferred from homology;
KW   DNA damage {ECO:0000256|RuleBase:RU367072};
KW   DNA repair {ECO:0000256|RuleBase:RU367072};
KW   Nucleus {ECO:0000256|RuleBase:RU367072}.
FT   DOMAIN          72..335
FT                   /note="MMS19 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF14500"
SQ   SEQUENCE   1228 AA;  136080 MW;  3FE31F6538F36725 CRC64;
     MSTYLEELAV RFVERDGLST DEHEKIAANA ADFVLHPEKH GSPTEPTVLI LVKSIHRWVF
     SGDDDDPSEF AEKNREKHAR GLKFLAMTLN ALPKDFLQST QIKMLASFFC SIYQQQDPAG
     LATATEAVLV LMSMANFPPS SADDIITSVG KMAPENFSKQ LAKDRLHILR VVKTLLLNPK
     SARVLQKRYE GSEFLLPILL LAKRERDPVN LLNWFRLLET LLKHNKISPE VATAAFESFS
     PFFPISIRRS TASGPDVTED ELKEALRSCF AANGLLAQHT FPFLLEKLDD GGSLTASAKL
     DILRTTRACV MSYEPVDTCL VPYVTKIWSS LKYEVRNGEV PEAVKETLSI FECLPQRLAS
     QPGTPDSALV DFLLQAWKDC VEDLENPTYT EQAGSILISV AGGGVVPFCH ICPRLLEAAR
     RNIAQPKSEV HTKYLLILLN NLLRTRLRLV SKLEAARDLD SSTEKQVFPG PDFDIPVSIV
     HDLYFKLFRE NTVERPTKEQ ADIAKEALKG LSLVVQQQKF TEDWKVVAAY DQDTLKEICT
     ALAYRATNCF NVPPTTTQEL QDIDKATVEA LKTTVKFFPE GYGKILAGVL SEVRRRDWEK
     SPAERTFNDL HALCQRVAFI GCTDVPVCPT PIINFAAFTG TMLHMLSYLL DERINLKACA
     IVADALATGM AYFSRTCEGK SLKTSGSTVA PWDTSNVEHE VHKGLSGFPH LVHGAVDKFD
     PVELVQSAKP TEHDVFTSFL LLGVYTLSEL YRHATTTGSG GESDLNWHLR IRGRSNAEPD
     DQESGRFIQA YLEEVGLAAT TVIRELSPSA QKDMDLAAQM IWYFQGLGAD SLLEKQDIGL
     LGKKEGFALT CGIARGIRPE IVSRMSDVKL RALLVGGFNS PKGFGQSGST ARPRIQAVQD
     HVAFLLANKY NTRAQAAPED GETALNHDAW IGVLSHIEKV FNNETGADLD DYSRFTAILA
     GAFARRDKYI TSGLTTALSH AAAKGSKEMS PQIARILSQL FATSKALDPA NHTIQKPLYL
     QWTYHQCVHP ILQLAYPLSQ QTTPGPSTDS TIYAIYVLHA VKRLSFQHYA PDAASIVRVV
     LAAMQKAADN YDVEAASTVT LQILHREPTL FRGHVSSVVA AAKRVYEKTV LDPSLSRVGS
     AVEGDWPAGP VAVLDGGDKR FRYEGDREKI RKMSFRILQM LPVQFEETIV RPHADEVRVH
     LSWALGDRVR EVRRVAEVAQ GAWAKVST
//