ID   A0A194VTK1_9PEZI        Unreviewed;       573 AA.
AC   A0A194VTK1;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Frizzled/smoothened-like sans CRD protein B {ECO:0000313|EMBL:KUI67258.1};
GN   ORFNames=VM1G_02695 {ECO:0000313|EMBL:KUI67258.1};
OS   Valsa mali.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Diaporthales; Valsaceae; Valsa.
OX   NCBI_TaxID=105487 {ECO:0000313|EMBL:KUI67258.1};
RN   [1] {ECO:0000313|EMBL:KUI67258.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=03-8 {ECO:0000313|EMBL:KUI67258.1};
RA   Yin Z., Liu H., Gao X., Li Z., Song N., Ke X., Dai Q., Wu Y., Sun Y.,
RA   Xu J.-R., Kang Z.K., Wang L., Huang L.;
RT   "Genome Sequence of Valsa Canker Pathogens Uncovers a Specific Adaption of
RT   Colonization on Woody Bark.";
RL   Submitted (DEC-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; CM003100; KUI67258.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A194VTK1; -.
DR   OrthoDB; 1360712at2759; -.
DR   Proteomes; UP000078559; Chromosome 3.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.
DR   Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR   InterPro; IPR017981; GPCR_2-like_7TM.
DR   InterPro; IPR000832; GPCR_2_secretin-like.
DR   PANTHER; PTHR42058:SF1; -; 1.
DR   PANTHER; PTHR42058; G_PROTEIN_RECEP_F2_4 DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF00002; 7tm_2; 1.
DR   PROSITE; PS50261; G_PROTEIN_RECEP_F2_4; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        63..84
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        91..112
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        132..153
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        174..196
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        216..239
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        286..308
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        347..372
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          54..218
FT                   /note="G-protein coupled receptors family 2 profile 2"
FT                   /evidence="ECO:0000259|PROSITE:PS50261"
FT   REGION          435..573
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        448..465
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        502..522
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        523..547
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        548..573
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   573 AA;  63021 MW;  E2B860E098BDB775 CRC64;
     MTTNITAFEC PAPFLNELQF GNGGYVEGRL CMSVGEISCC LPCPLTAWAY PDSFDTMGIA
     ADWVAVASTV CCVFLLLSWL VLPIDKTHRH YLSICLTFAV VFMNLGFVIP LAGNPEQCYD
     SITPNDMQTS SVCAASGTFI VIGGWAGVLW IFLRSLSLHL QICWQVVVGR NFMWFSHAVG
     WGLPALGIIL ALTLSGVSFR FGATCHINHE NSLADLWIPL LVFAGLTIII QFATFGYCIK
     VYLASLADNN ATTENSAGLP SYTNSIRTMT PRQAYRRVRR VIQLQWRGIA IVLIIIADVV
     FFAVVFVFQD NTIEEVKNDP QIAEPWIDCL LAAGGDKNKC LNQTNSLVVS MATIGAVLVL
     LAMNGIWLLV LLGRWSMVTG WVELFTHRPS QAKREFVSVD ARLDDMKMNT DPRSYEMLSR
     DSGKNVMMDG MVTPDTVREG PIYPPIGSYL ASTTSPPNES PTPSGRRTPD YFGPQARYQA
     PVRSFSSPRP PTREGRGSQA GWEATATYSN VGREFSRSPP PTGQYSQSPP PTGQYSQSPP
     PTGQYSQSPP PSGHYHQDSY GQQDMNPLGM NRI
//