ID A0A194W764_9PEZI Unreviewed; 281 AA.
AC A0A194W764;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Beta-lactamase-like protein 2 {ECO:0000313|EMBL:KUI71923.1};
GN ORFNames=VM1G_07896 {ECO:0000313|EMBL:KUI71923.1};
OS Valsa mali.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Diaporthales; Valsaceae; Valsa.
OX NCBI_TaxID=105487 {ECO:0000313|EMBL:KUI71923.1};
RN [1] {ECO:0000313|EMBL:KUI71923.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=03-8 {ECO:0000313|EMBL:KUI71923.1};
RA Yin Z., Liu H., Gao X., Li Z., Song N., Ke X., Dai Q., Wu Y., Sun Y.,
RA Xu J.-R., Kang Z.K., Wang L., Huang L.;
RT "Genome Sequence of Valsa Canker Pathogens Uncovers a Specific Adaption of
RT Colonization on Woody Bark.";
RL Submitted (DEC-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SIMILARITY: Belongs to the metallo-beta-lactamase superfamily.
CC {ECO:0000256|ARBA:ARBA00007749}.
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DR EMBL; CM003105; KUI71923.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A194W764; -.
DR OrthoDB; 295731at2759; -.
DR Proteomes; UP000078559; Chromosome 8.
DR GO; GO:0008800; F:beta-lactamase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0017001; P:antibiotic catabolic process; IEA:InterPro.
DR GO; GO:0009058; P:biosynthetic process; IEA:UniProt.
DR CDD; cd07722; LACTB2-like_MBL-fold; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR001018; Beta-lactamase_class-B_CS.
DR InterPro; IPR047921; LACTB2-like_MBL-fold.
DR InterPro; IPR041516; LACTB2_WH.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR23131; ENDORIBONUCLEASE LACTB2; 1.
DR PANTHER; PTHR23131:SF0; ENDORIBONUCLEASE LACTB2; 1.
DR Pfam; PF17778; BLACT_WH; 1.
DR Pfam; PF00753; Lactamase_B; 2.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
DR PROSITE; PS00743; BETA_LACTAMASE_B_1; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
FT DOMAIN 33..187
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
SQ SEQUENCE 281 AA; 30789 MW; EE22A09F69CAC91A CRC64;
MAVQLTHLPE VERVSPICIR ILGGNPGKFT LQGTNTYILG SGRRRLLIDT GEGKPSWIAA
VKQTLADENA TVSETLISHW HGDHQGGIQD LLALSPETKV YKNQPDKGQL GITDGQKFEV
EGATLTAVHT PGHAVDHMVF VLDQEDAMFT ADNVLGQGTA VFEDLATYLA SLQKMKTLFK
AKAYPGHGPV IDDGPAKIEE YITHRQQRED QITQTLSSVN KETGTAAWEP IQLVKVIYHD
VPESLHLPAQ GGVIQVLQKL EKEGKASRES NRWSLTDRSA L
//
