ID   A0A195AY21_9HYME        Unreviewed;       537 AA.
AC   A0A195AY21;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   24-JAN-2024, entry version 23.
DE   SubName: Full=ATP-dependent DNA helicase 2 subunit 1 {ECO:0000313|EMBL:KYM77101.1};
GN   ORFNames=ALC53_12395 {ECO:0000313|EMBL:KYM77101.1};
OS   Atta colombica.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC   Formicidae; Myrmicinae; Atta.
OX   NCBI_TaxID=520822 {ECO:0000313|EMBL:KYM77101.1, ECO:0000313|Proteomes:UP000078540};
RN   [1] {ECO:0000313|EMBL:KYM77101.1, ECO:0000313|Proteomes:UP000078540}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Treedump-2 {ECO:0000313|EMBL:KYM77101.1};
RC   TISSUE=Whole body {ECO:0000313|EMBL:KYM77101.1};
RA   Nygaard S., Hu H., Boomsma J., Zhang G.;
RT   "Atta colombica WGS genome.";
RL   Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the ku70 family.
CC       {ECO:0000256|ARBA:ARBA00005240}.
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DR   EMBL; KQ976703; KYM77101.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A195AY21; -.
DR   STRING; 520822.A0A195AY21; -.
DR   Proteomes; UP000078540; Unassembled WGS sequence.
DR   GO; GO:0043564; C:Ku70:Ku80 complex; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0042162; F:telomeric DNA binding; IEA:InterPro.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006303; P:double-strand break repair via nonhomologous end joining; IEA:InterPro.
DR   GO; GO:0000723; P:telomere maintenance; IEA:InterPro.
DR   Gene3D; 1.10.1600.10; -; 1.
DR   Gene3D; 2.40.290.10; -; 1.
DR   Gene3D; 4.10.970.10; Ku70, bridge and pillars; 1.
DR   Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR   InterPro; IPR006165; Ku70.
DR   InterPro; IPR006164; Ku70/Ku80_beta-barrel_dom.
DR   InterPro; IPR027388; Ku70_bridge/pillars_dom_sf.
DR   InterPro; IPR005161; Ku_N.
DR   InterPro; IPR016194; SPOC-like_C_dom_sf.
DR   InterPro; IPR036465; vWFA_dom_sf.
DR   PANTHER; PTHR12604; KU AUTOANTIGEN DNA HELICASE; 1.
DR   PANTHER; PTHR12604:SF2; X-RAY REPAIR CROSS-COMPLEMENTING PROTEIN 6; 1.
DR   Pfam; PF02735; Ku; 1.
DR   Pfam; PF03731; Ku_N; 1.
DR   PIRSF; PIRSF003033; Ku70; 1.
DR   SUPFAM; SSF100939; SPOC domain-like; 1.
DR   SUPFAM; SSF53300; vWA-like; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW   DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW   DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:KYM77101.1};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000078540}.
FT   DOMAIN          25..217
FT                   /note="Ku70/Ku80 N-terminal alpha/beta"
FT                   /evidence="ECO:0000259|Pfam:PF03731"
FT   DOMAIN          244..449
FT                   /note="Ku"
FT                   /evidence="ECO:0000259|Pfam:PF02735"
SQ   SEQUENCE   537 AA;  62706 MW;  F23A09E129A886AF CRC64;
     MSITEMSQDE EVDSQTSQWY GVREATLFLV DCTKKMFMHS SDIDDKKITY IEKFFKLYKQ
     ILRQKLAWSM QDWMGVVLFG TEKSDSNSPW TNIRTLQELR VVTLDDLQQI RKLSNGMKGY
     ESMKLKNNIL LLDALTYATD IFLKIKTVLT KRRIVLITCY DPDYSDDEKH RIRAKAKSLK
     ELDINLHVID LRNNWPLDEF YKDLEILSRK IEISVYRRTS LVDLVQQIKA PSKNIARLSF
     QICDGVEIDL VVRTLGRKRR YLQTKPLSKA TNQVLSRSTY FKDTNFSIDE EDSDNEESDL
     PFMIPEEVNL ETKELIGGKK LRFTRKELLR IKHLYPPAIK IIGVRPIPSD LFRYHVKRKY
     FVRADYGSTR KDNLLFFSAL LNKCATKNKM IVCAFTMRLN TQTNLCYMIP NAELGGFYLS
     KVAFQGNVGD KSEALLHYDT QNSVSDKEVA LWKKTIDRLD MNYHPYNFRS YKLECQIQIV
     EKLALDKEPG PPPIDSIEKS YLIAKQKTSD LISEFYNMYP DLLFVNGPTK AKRTKKK
//