ID   A0A195B6P3_9HYME        Unreviewed;       725 AA.
AC   A0A195B6P3;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Hormone-sensitive lipase {ECO:0000313|EMBL:KYM79854.1};
GN   ORFNames=ALC53_09776 {ECO:0000313|EMBL:KYM79854.1};
OS   Atta colombica.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC   Formicidae; Myrmicinae; Atta.
OX   NCBI_TaxID=520822 {ECO:0000313|EMBL:KYM79854.1, ECO:0000313|Proteomes:UP000078540};
RN   [1] {ECO:0000313|EMBL:KYM79854.1, ECO:0000313|Proteomes:UP000078540}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Treedump-2 {ECO:0000313|EMBL:KYM79854.1};
RC   TISSUE=Whole body {ECO:0000313|EMBL:KYM79854.1};
RA   Nygaard S., Hu H., Boomsma J., Zhang G.;
RT   "Atta colombica WGS genome.";
RL   Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KQ976582; KYM79854.1; -; Genomic_DNA.
DR   RefSeq; XP_018052258.1; XM_018196769.1.
DR   AlphaFoldDB; A0A195B6P3; -.
DR   STRING; 520822.A0A195B6P3; -.
DR   GeneID; 108689829; -.
DR   OrthoDB; 2941058at2759; -.
DR   Proteomes; UP000078540; Unassembled WGS sequence.
DR   GO; GO:0016298; F:lipase activity; IEA:InterPro.
DR   GO; GO:0008203; P:cholesterol metabolic process; IEA:InterPro.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:InterPro.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 2.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR013094; AB_hydrolase_3.
DR   InterPro; IPR010468; HSL_N.
DR   PANTHER; PTHR23025:SF3; HORMONE-SENSITIVE LIPASE; 1.
DR   PANTHER; PTHR23025; TRIACYLGLYCEROL LIPASE; 1.
DR   Pfam; PF07859; Abhydrolase_3; 2.
DR   Pfam; PF06350; HSL_N; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE   4: Predicted;
KW   Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW   Reference proteome {ECO:0000313|Proteomes:UP000078540}.
FT   DOMAIN          22..324
FT                   /note="Hormone-sensitive lipase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF06350"
FT   DOMAIN          341..490
FT                   /note="Alpha/beta hydrolase fold-3"
FT                   /evidence="ECO:0000259|Pfam:PF07859"
FT   DOMAIN          638..699
FT                   /note="Alpha/beta hydrolase fold-3"
FT                   /evidence="ECO:0000259|Pfam:PF07859"
SQ   SEQUENCE   725 AA;  81287 MW;  91025F6B06C21FC0 CRC64;
     MSTCNDDFER PFDFEPQQLD EWNTLRDLCC ANEKYFDSHQ DKNGIKIRAA LVAIKDYLTD
     LQPLYREIAR FASHFDFDED NPGNGYRSFL LLVDKCIMYS ELICRQIHDQ KDSVFFRKSY
     YMKEIEACSQ LLASLFTCLQ HLKTMYSWST EVMNDGKLSL YPLEQYNTQE LLNSAQNVNQ
     YCFYGRCLGF QFCDSLKHVL KTLSFFMASF SEMYYSNSTL LGLCTNSIKY LLDPEARARR
     IVNISQHADI SFCQAFWFLS ESAIMNIINT SNLAINQVIS IPPEELVLPT LDEGIISVPI
     PNSHIGKKPI HVRLLSSKRR LGMVGSGGIG GTLCDLCDEL IIHTHGGGFV SQTSRSHEIY
     LRNWTVTLEV PILSIDYSLA PEAPYPRALE EVLYAYAWAL KHANTLLGST AKKVIFVGDS
     AGGNINLGVI LRCMQLNIRR PDGIFMAYAP VRIECIPSPS RMLCLTDPLL PFGFMLRCLK
     AYVADNKKST KEHENEDVKS DTESFAEVSE SDLIALALSP NGDGANDDQK LVSLPSDSTL
     NSVSLTEVDG AECPKAQAKS REYINRFLNM YRNSGLASTS SPVAMNGSVS RNGNSSGQSN
     KSWSLFGWSF GRRSSKDSRE LNMENTISSE EFVFAIPKDP FLSPYDAPDN MLANIPPIKI
     LTCHLDPCLD DCIMFARKLR SLGNKVTLDI LPGLPHGFLS LVQTSKEAME GSEICVGRIK
     ELLEL
//