ID A0A195BA40_9HYME Unreviewed; 686 AA.
AC A0A195BA40;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 28-JUN-2023, entry version 27.
DE RecName: Full=Protein hook {ECO:0000256|ARBA:ARBA00018971};
GN ORFNames=ALC53_08405 {ECO:0000313|EMBL:KYM81064.1};
OS Atta colombica.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Myrmicinae; Atta.
OX NCBI_TaxID=520822 {ECO:0000313|EMBL:KYM81064.1, ECO:0000313|Proteomes:UP000078540};
RN [1] {ECO:0000313|EMBL:KYM81064.1, ECO:0000313|Proteomes:UP000078540}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Treedump-2 {ECO:0000313|EMBL:KYM81064.1};
RC TISSUE=Whole body {ECO:0000313|EMBL:KYM81064.1};
RA Nygaard S., Hu H., Boomsma J., Zhang G.;
RT "Atta colombica WGS genome.";
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Homodimer. Interacts with microtubules via its N-terminus.
CC {ECO:0000256|ARBA:ARBA00011241}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}. Endosome
CC {ECO:0000256|ARBA:ARBA00004177}.
CC -!- SIMILARITY: Belongs to the hook family.
CC {ECO:0000256|ARBA:ARBA00006946}.
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DR EMBL; KQ976542; KYM81064.1; -; Genomic_DNA.
DR RefSeq; XP_018050629.1; XM_018195140.1.
DR AlphaFoldDB; A0A195BA40; -.
DR STRING; 520822.A0A195BA40; -.
DR GeneID; 108688761; -.
DR OrthoDB; 50921at2759; -.
DR Proteomes; UP000078540; Unassembled WGS sequence.
DR GO; GO:0005768; C:endosome; IEA:UniProtKB-SubCell.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0031122; P:cytoplasmic microtubule organization; IEA:InterPro.
DR GO; GO:0030705; P:cytoskeleton-dependent intracellular transport; IEA:InterPro.
DR GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR CDD; cd22222; HkD_Hook; 1.
DR Gene3D; 1.10.418.10; Calponin-like domain; 1.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR008636; Hook_C.
DR InterPro; IPR043936; HOOK_N.
DR PANTHER; PTHR18947; HOOK PROTEINS; 1.
DR PANTHER; PTHR18947:SF39; PROTEIN HOOK; 1.
DR Pfam; PF05622; HOOK; 1.
DR Pfam; PF19047; HOOK_N; 1.
DR SUPFAM; SSF116907; Hook domain; 1.
DR PROSITE; PS50021; CH; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Endocytosis {ECO:0000256|ARBA:ARBA00022583};
KW Endosome {ECO:0000256|ARBA:ARBA00022753};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Reference proteome {ECO:0000313|Proteomes:UP000078540}.
FT DOMAIN 5..121
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT REGION 664..686
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 180..214
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 247..325
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 364..422
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 472..561
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 686 AA; 80458 MW; 135017A461969B4D CRC64;
MGDHRQQLDY LIKWLATFDL QAPHNSVEEI SDGVALAEAL AKIAPEWFTA VWKAKIKTDV
GTNWRLRVSN MKKIVEAVME YYVECLNQQL SNYVKPDATK IGEHCDSDEL RRLLQLILGC
AVNCNQKQLL ITRIMGMEET VQQVLMQSIQ EVNFESLVPD VPDSAQQRLY ADFQAAVDMR
DQLAQKCHEL DQQLSLLQEE KIALIAENKK LQERLDEFEN PEESFKYSER KQVEALKDEL
FKMETSRDDY RLKAELLEKE NLELQSRNEN LQKAADERNH LKDEVDALRE YKDKVERYEI
MIESYKKKIE DASDLKRQLK ILEDNSKENI QFKFKYEEEV KLTTKLRNHL ELCKQQRTEA
HHKLDEKSNK CDRLEFDCKK MEAKLGAVER ERDRLIVERD TLKEMNEELK CMQLQATENM
AKPSADSTSV SGSEMMPFEV KEKLFCLQME NKMMKIKLNG NEDKLPNIQA LLEDSEERFN
TKQEQLRKAN QRIMELETQL EETVGTQVSS SDNVSPNQKL SQLQDELRKV QADKERLTLQ
LEERESALQT QKQEAFALQE KLTRKKYENA ALEERHKKYI EKAKSVIKSL DPKQNNSSPN
EVIMLRNQLM EQRKMIEDME RSMKESRLLR EMEEKLMVTA FHRLGGNCHR EVMDQRLAAL
SAGQGQSFLA RQRQPVSRRY PPYNSK
//
