ID A0A195BQZ5_9HYME Unreviewed; 1025 AA.
AC A0A195BQZ5;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE SubName: Full=Rho guanine nucleotide exchange factor 7 {ECO:0000313|EMBL:KYM88558.1};
GN ORFNames=ALC53_03041 {ECO:0000313|EMBL:KYM88558.1};
OS Atta colombica.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Myrmicinae; Atta.
OX NCBI_TaxID=520822 {ECO:0000313|EMBL:KYM88558.1, ECO:0000313|Proteomes:UP000078540};
RN [1] {ECO:0000313|EMBL:KYM88558.1, ECO:0000313|Proteomes:UP000078540}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Treedump-2 {ECO:0000313|EMBL:KYM88558.1};
RC TISSUE=Whole body {ECO:0000313|EMBL:KYM88558.1};
RA Nygaard S., Hu H., Boomsma J., Zhang G.;
RT "Atta colombica WGS genome.";
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell projection, lamellipodium
CC {ECO:0000256|ARBA:ARBA00004510}.
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DR EMBL; KQ976424; KYM88558.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A195BQZ5; -.
DR STRING; 520822.A0A195BQZ5; -.
DR Proteomes; UP000078540; Unassembled WGS sequence.
DR GO; GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR CDD; cd01225; PH_Cool_Pix; 1.
DR CDD; cd00160; RhoGEF; 1.
DR CDD; cd11877; SH3_PIX; 1.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR Gene3D; 1.20.5.390; L1 transposable element, trimerization domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000219; DH-domain.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR046376; PH_Cool_Pix.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR46026; RHO-TYPE GUANINE NUCLEOTIDE EXCHANGE FACTOR, ISOFORM F; 1.
DR PANTHER; PTHR46026:SF1; RHO-TYPE GUANINE NUCLEOTIDE EXCHANGE FACTOR, ISOFORM F; 1.
DR Pfam; PF00169; PH; 1.
DR Pfam; PF00621; RhoGEF; 1.
DR Pfam; PF00018; SH3_1; 1.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00233; PH; 1.
DR SMART; SM00325; RhoGEF; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50010; DH_2; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000078540};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 5..64
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 90..269
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
FT DOMAIN 297..394
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 66..86
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 981..1008
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1025 AA; 116392 MW; 39BE5B62BB7956B6 CRC64;
MSKSDAPKFV TALFSFKGKN NDELCFKKGD VITITQVDDE GWWEGTLHDK TGWFPSNYVK
EYRAPDGSHA SIKTSPERSP QESPAHQKLN RDIVLKDIVD SERVNVAELQ GLVNNFLQPL
ETSTILKKDE YKQLLGNIHE VLETHQCLLA NLEGTVLQGL SARVGNLFLT IALRLKSIHT
TYCNNHPQAV CILDRYRDEL NEFMERSGAI SPGILVLTTG LSKPFRRLDK YSAMLQELER
YTEKNHPDRG DTQRSITVYR EIADHCASIR KQRELALQIL TSGIKGWEGE ELNSLGEIIH
VGSVTLATGV DRRDRYFVLF PTTLLVLSTS PRMSSFIYEG KLPLTGINVT GIEDTDDIRN
ALEITGPMIE SIVVLCATRE ERQRWINLLI QEQCTSLLKS PTTPRVSCHH PPYARLSRYF
AKLVRRKVIY PELMKKLLYI QYILKPDLTN VKMRKCNVTY TIFPTHTSEE SEISDTFDEN
NVKEESRILR KSSLILDVRY VLDNTDLSTV GLASTSSLTN FAPRVDCDNR CTFETSKSLP
AGAMSHVLPN VPLASSKSYT SNLQTCNKFC REHLEISHDR DQTVNYKYLR AIEEFSKNLD
VPVQYSNQND NCDNNIGKEF GETCVNISLR SSDSGMAESY HLRSSEINSC YKSYTSSHTK
YTDPVRTSHS ESDNDENKFE HQCICTSPFG STPRDSAHSV ASSKIIDECP TLVRPNDVGN
DVNDNSGKKI QETVLVHPLI NYGNVQEKRY TQPIPYAHQC VIKKIGRRIV RPIQPIIEEY
DEPTNQVYSS GLYAHWWLKK SIPIVGCTEQ GKLPWHGCSF DHFSFFNHAG VFTNYHFLPK
VVCSYFTAML CEQTNNQLNG KHQRSAMEHC TSPGIKTPWS IASLRPAPPL YSLKNFGKLD
TTTDTSRSPR LCNERQFEED AIILKVIEGY CLSVNARFTV HSGESNSMLD YESQKSRDRI
SLTHNRGNWE YCNDKTLSET VKTLKNQMTD LQSQMSLLTK QLDEERRSRL SLAATVKRSM
GVIDA
//
