ID   A0A195CD05_9HYME        Unreviewed;       406 AA.
AC   A0A195CD05;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   RecName: Full=DNA/RNA non-specific endonuclease domain-containing protein {ECO:0000259|SMART:SM00892};
GN   ORFNames=ALC62_10712 {ECO:0000313|EMBL:KYM98744.1};
OS   Cyphomyrmex costatus.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC   Formicidae; Myrmicinae; Cyphomyrmex.
OX   NCBI_TaxID=456900 {ECO:0000313|EMBL:KYM98744.1, ECO:0000313|Proteomes:UP000078542};
RN   [1] {ECO:0000313|EMBL:KYM98744.1, ECO:0000313|Proteomes:UP000078542}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MS0001 {ECO:0000313|EMBL:KYM98744.1};
RC   TISSUE=Whole body {ECO:0000313|EMBL:KYM98744.1};
RA   Nygaard S., Hu H., Boomsma J., Zhang G.;
RT   "Cyphomyrmex costatus WGS genome.";
RL   Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; KQ977935; KYM98744.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A195CD05; -.
DR   STRING; 456900.A0A195CD05; -.
DR   Proteomes; UP000078542; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   Gene3D; 3.40.570.10; Extracellular Endonuclease, subunit A; 1.
DR   InterPro; IPR001604; DNA/RNA_non-sp_Endonuclease.
DR   InterPro; IPR044929; DNA/RNA_non-sp_Endonuclease_sf.
DR   InterPro; IPR044925; His-Me_finger_sf.
DR   InterPro; IPR040255; Non-specific_endonuclease.
DR   PANTHER; PTHR13966; ENDONUCLEASE RELATED; 1.
DR   PANTHER; PTHR13966:SF19; NUCLEASE EXOG, MITOCHONDRIAL; 1.
DR   Pfam; PF01223; Endonuclease_NS; 1.
DR   SMART; SM00892; Endonuclease_NS; 1.
DR   SUPFAM; SSF54060; His-Me finger endonucleases; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|PIRSR:PIRSR640255-2};
KW   Reference proteome {ECO:0000313|Proteomes:UP000078542};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..17
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           18..406
FT                   /note="DNA/RNA non-specific endonuclease domain-containing
FT                   protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5008269944"
FT   DOMAIN          149..389
FT                   /note="DNA/RNA non-specific endonuclease"
FT                   /evidence="ECO:0000259|SMART:SM00892"
FT   ACT_SITE        237
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR640255-1"
FT   BINDING         267
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT                   /ligand_note="catalytic"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR640255-2"
SQ   SEQUENCE   406 AA;  46502 MW;  9DD480D01610D75F CRC64;
     MLLVIPFLAC YIVWAIANPI NIGISCTISV QYKIGDLKEP QPLLLKRVGK HATIWYPDND
     NGTLKISAGD SIYLACPGKN NNFKNRSWGN EVEAVCVRDK VFDVKGVHQY ISSLVCKSHP
     EHHAEYTGTS PCLGRHSPIE IGFNVSGTFI RTIELCRDEK TYMTYYTKFK MTKMIESYQR
     SYPRPSKFLA GKFYPGINVD YLYKFETQSD TLARILKSTK LTEERLKKSL QFLSRGHLVA
     KADFVYGIQQ RSTFWYLNTA PQWRTFNAGN WNSLEVSVRR FAANRRLDLD VYTGVHGQMT
     MEDIHNKQQP VYLHAEGAVM SVPKFYWKVI YDPLSKRGTA FVGLNDPFIT LVTDDVYLCS
     DISERIKWLD WRPRNITLGI SYACSVADLR KAVPVVPLLD IIDILM
//