ID A0A195CT28_9HYME Unreviewed; 385 AA.
AC A0A195CT28;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 28-JUN-2023, entry version 22.
DE RecName: Full=26S proteasome non-ATPase regulatory subunit 13 {ECO:0000256|ARBA:ARBA00015732};
DE AltName: Full=26S proteasome regulatory subunit RPN9 {ECO:0000256|ARBA:ARBA00029749};
DE AltName: Full=26S proteasome regulatory subunit S11 {ECO:0000256|ARBA:ARBA00032323};
DE AltName: Full=26S proteasome regulatory subunit p40.5 {ECO:0000256|ARBA:ARBA00031303};
GN ORFNames=ALC62_05947 {ECO:0000313|EMBL:KYN03284.1};
OS Cyphomyrmex costatus.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Myrmicinae; Cyphomyrmex.
OX NCBI_TaxID=456900 {ECO:0000313|EMBL:KYN03284.1, ECO:0000313|Proteomes:UP000078542};
RN [1] {ECO:0000313|EMBL:KYN03284.1, ECO:0000313|Proteomes:UP000078542}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MS0001 {ECO:0000313|EMBL:KYN03284.1};
RC TISSUE=Whole body {ECO:0000313|EMBL:KYN03284.1};
RA Nygaard S., Hu H., Boomsma J., Zhang G.;
RT "Cyphomyrmex costatus WGS genome.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Component of the 26S proteasome, a multiprotein complex
CC involved in the ATP-dependent degradation of ubiquitinated proteins.
CC This complex plays a key role in the maintenance of protein homeostasis
CC by removing misfolded or damaged proteins, which could impair cellular
CC functions, and by removing proteins whose functions are no longer
CC required. Therefore, the proteasome participates in numerous cellular
CC processes, including cell cycle progression, apoptosis, or DNA damage
CC repair. {ECO:0000256|ARBA:ARBA00002362}.
CC -!- SUBUNIT: Component of the 19S proteasome regulatory particle complex.
CC The 26S proteasome consists of a 20S core particle (CP) and two 19S
CC regulatory subunits (RP). The regulatory particle is made of a lid
CC composed of 9 subunits including PSMD13, a base containing 6 ATPases
CC and few additional components. {ECO:0000256|ARBA:ARBA00011441}.
CC -!- SIMILARITY: Belongs to the proteasome subunit S11 family.
CC {ECO:0000256|ARBA:ARBA00006207}.
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DR EMBL; KQ977372; KYN03284.1; -; Genomic_DNA.
DR RefSeq; XP_018394953.1; XM_018539451.1.
DR AlphaFoldDB; A0A195CT28; -.
DR STRING; 456900.A0A195CT28; -.
DR GeneID; 108773596; -.
DR OrthoDB; 101547at2759; -.
DR Proteomes; UP000078542; Unassembled WGS sequence.
DR GO; GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
DR InterPro; IPR000717; PCI_dom.
DR InterPro; IPR035298; PSMD13.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR10539; 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 13; 1.
DR PANTHER; PTHR10539:SF0; 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 13; 1.
DR Pfam; PF01399; PCI; 1.
DR SMART; SM00088; PINT; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50250; PCI; 1.
PE 3: Inferred from homology;
KW Proteasome {ECO:0000313|EMBL:KYN03284.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000078542}.
FT DOMAIN 179..346
FT /note="PCI"
FT /evidence="ECO:0000259|PROSITE:PS50250"
SQ SEQUENCE 385 AA; 43631 MW; FA8FC37A4175A5F3 CRC64;
MAVTVAVKDL NTFLSQKQNV ADKELAAEWA QLEELYSKRL WHQLTLKLET FVKHPVLQQE
DNLVQLYVNF LSTFENKINP LSLVEILAHV VPQLQDNQDA IKFLEKTETK VQSNNEAVAL
CKVLKGQILL DKLNNQEQAK KIIEEVEAML DNADGITTVH GRFYLLASRL YRLQGKHAEY
YRTALRYLGC IELSSLNRQE QEQHAFFLGL AALLGEGVYN LGELLAHPVL ESLKGTPNNW
LVDLLQAFNA GDIVALERLK PQWSKVADLA AQELKLRQKI SLLCLMEMTF KRQANNRQLT
FTEISQETRL PLGEVELLVM KALAQGLVRG AIDQVAGTVN MTWVQPRVLD RSQIAGMVQR
LDGWCKDVSS MEKLLESRAS EILTL
//
