ID A0A195DSY6_9HYME Unreviewed; 3164 AA.
AC A0A195DSY6;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=Protocadherin-like wing polarity protein stan {ECO:0000313|EMBL:KYN15907.1};
GN ORFNames=ALC57_11876 {ECO:0000313|EMBL:KYN15907.1};
OS Trachymyrmex cornetzi.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Myrmicinae; Trachymyrmex.
OX NCBI_TaxID=471704 {ECO:0000313|EMBL:KYN15907.1, ECO:0000313|Proteomes:UP000078492};
RN [1] {ECO:0000313|EMBL:KYN15907.1, ECO:0000313|Proteomes:UP000078492}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tcor2-1 {ECO:0000313|EMBL:KYN15907.1};
RC TISSUE=Whole body {ECO:0000313|EMBL:KYN15907.1};
RA Nygaard S., Hu H., Boomsma J., Zhang G.;
RT "Trachymyrmex cornetzi WGS genome.";
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; KQ980487; KYN15907.1; -; Genomic_DNA.
DR STRING; 471704.A0A195DSY6; -.
DR Proteomes; UP000078492; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005509; F:calcium ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR GO; GO:0048513; P:animal organ development; IEA:UniProt.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProt.
DR GO; GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.
DR GO; GO:0016043; P:cellular component organization; IEA:UniProt.
DR GO; GO:0001736; P:establishment of planar polarity; IEA:UniProt.
DR GO; GO:0007163; P:establishment or maintenance of cell polarity; IEA:UniProt.
DR GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IEA:InterPro.
DR GO; GO:0048731; P:system development; IEA:UniProt.
DR CDD; cd15441; 7tmB2_CELSR_Adhesion_IV; 1.
DR CDD; cd11304; Cadherin_repeat; 9.
DR CDD; cd00054; EGF_CA; 2.
DR CDD; cd00055; EGF_Lam; 1.
DR CDD; cd00110; LamG; 2.
DR Gene3D; 2.60.120.200; -; 2.
DR Gene3D; 2.60.220.50; -; 1.
DR Gene3D; 2.60.40.60; Cadherins; 9.
DR Gene3D; 4.10.1240.10; GPCR, family 2, extracellular hormone receptor domain; 1.
DR Gene3D; 2.10.25.10; Laminin; 2.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR Gene3D; 2.170.300.10; Tie2 ligand-binding domain superfamily; 1.
DR InterPro; IPR002126; Cadherin-like_dom.
DR InterPro; IPR015919; Cadherin-like_sf.
DR InterPro; IPR020894; Cadherin_CS.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR032471; GAIN_dom_N.
DR InterPro; IPR046338; GAIN_dom_sf.
DR InterPro; IPR017981; GPCR_2-like_7TM.
DR InterPro; IPR036445; GPCR_2_extracell_dom_sf.
DR InterPro; IPR001879; GPCR_2_extracellular_dom.
DR InterPro; IPR000832; GPCR_2_secretin-like.
DR InterPro; IPR000203; GPS.
DR InterPro; IPR001791; Laminin_G.
DR InterPro; IPR002049; LE_dom.
DR PANTHER; PTHR24026; FAT ATYPICAL CADHERIN-RELATED; 1.
DR PANTHER; PTHR24026:SF51; PROTOCADHERIN-LIKE WING POLARITY PROTEIN STAN; 1.
DR Pfam; PF00002; 7tm_2; 1.
DR Pfam; PF00028; Cadherin; 8.
DR Pfam; PF00008; EGF; 2.
DR Pfam; PF16489; GAIN; 1.
DR Pfam; PF01825; GPS; 1.
DR Pfam; PF00053; Laminin_EGF; 1.
DR Pfam; PF02210; Laminin_G_2; 2.
DR PRINTS; PR00205; CADHERIN.
DR PRINTS; PR00249; GPCRSECRETIN.
DR SMART; SM00112; CA; 9.
DR SMART; SM00181; EGF; 7.
DR SMART; SM00179; EGF_CA; 2.
DR SMART; SM00180; EGF_Lam; 1.
DR SMART; SM00303; GPS; 1.
DR SMART; SM00008; HormR; 1.
DR SMART; SM00282; LamG; 2.
DR SUPFAM; SSF49313; Cadherin-like; 9.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 2.
DR SUPFAM; SSF57196; EGF/Laminin; 1.
DR PROSITE; PS00232; CADHERIN_1; 6.
DR PROSITE; PS50268; CADHERIN_2; 8.
DR PROSITE; PS00022; EGF_1; 3.
DR PROSITE; PS50026; EGF_3; 4.
DR PROSITE; PS01248; EGF_LAM_1; 1.
DR PROSITE; PS50027; EGF_LAM_2; 1.
DR PROSITE; PS50227; G_PROTEIN_RECEP_F2_3; 1.
DR PROSITE; PS50261; G_PROTEIN_RECEP_F2_4; 1.
DR PROSITE; PS50221; GPS; 1.
DR PROSITE; PS50025; LAM_G_DOMAIN; 2.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837, ECO:0000256|PROSITE-
KW ProRule:PRU00043}; Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Laminin EGF-like domain {ECO:0000256|ARBA:ARBA00023292,
KW ECO:0000256|PROSITE-ProRule:PRU00460};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000078492};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..3164
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5008270528"
FT TRANSMEM 2507..2528
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2540..2558
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2578..2598
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2610..2630
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2650..2670
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2691..2713
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2719..2742
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 262..366
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 367..483
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 484..590
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 591..701
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 702..804
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 805..912
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 913..1016
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1017..1123
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1386..1422
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1468..1668
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 1671..1707
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1711..1875
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 1877..1912
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1913..1952
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 2009..2056
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 2041..2115
FT /note="G-protein coupled receptors family 2 profile 1"
FT /evidence="ECO:0000259|PROSITE:PS50227"
FT DOMAIN 2502..2743
FT /note="G-protein coupled receptors family 2 profile 2"
FT /evidence="ECO:0000259|PROSITE:PS50261"
FT REGION 2805..2906
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2973..3019
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3056..3103
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2805..2846
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2847..2878
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2973..2997
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3056..3097
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 1412..1421
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 1697..1706
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 1881..1891
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 1902..1911
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 2009..2021
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 2011..2028
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 2030..2039
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
SQ SEQUENCE 3164 AA; 348263 MW; 77FD7F9922079B62 CRC64;
MARWRWMLLI LTTIWTLGDG YLTVLPSSTP VGTVVFEAGV PQLGGRRKYE ASSERTAWFA
RKLLKVHPHT GRVTLAKTLS CEGLQYPRVF TFYVDSTSSR LGRPTIDYYS LPLRILITGC
GGENHDLAAT RGWMAETLAS YAMPSTDRFT EVCLRTSQLV AALRDFLPQT TLKECETRWG
GVADPRFLVE GAAGDLVSAT EQCLVDPLWK VSVSMNLRCT GDSRLTDAEH RLKIVFHHHQ
LDDTDLGRRV RRELKNQSPY FEQHLYLAAV EEEKEPGMYV TSVKARDPEN GAVRYSMSSL
VDARSQALLA LDPVTGRVTT RARLDRENVD VHYFRVLAVD DSFPPRTGTT TLQVNVLDAN
DHTPSFEGPE YDASVREGVP VGSTVITVKA TDQDTGRNAE VEYSIVSITA GSSITHMEDA
ATFRIDPRSG VVTTRTPLDR EQTEIYTVVL SVTDQATPPS TRRSSNATLV VRVLDDNDNY
PQFTERTYSA TVPEDLDYTT NPVIARIRAM DADAGANAAV RYAIIGGNTQ NTFSIDSMSG
DVALVKPLDY ESTRSYKIVI RAQDGGSPAR SNTTQLLVMV RDVNDNAPRF YTSHFQEAVS
ESVPVGYSIL RVQAYDADEG NNALIKYTIG ARDFTGASTE NFPITVKAET GWIYTTKQLD
REQCSKYQFT VIAADSGEEP KSASATVFLT VTDVNDNDPY FEPKTYEAVV SEDSLAGTPV
TTVTATDPDE DSRIHYEITG GNTRGRFSIS SQNGRGLITI AQTLDYKQEK RFVLTVTASD
TGSRTDTALV YVNVSDANNY SPEFENAPYS VSVFEDAPIG VTVLVVSATD ADVGKNAQIT
YSLATDNGEQ VITEFTINPQ TGAITTTKAL DRESVPSYLL TVTARDGGVP SLSDTTDVEI
SVTDVNDNAP VFEAPHYHGS ILEDVLLSTS VLRVAATDAD TDLNGRVKYG LEDDGDGAFT
IDSTTGIIRT AKILDRESVA YYTLKAVATD RGSPALSSVV PVTIKIEDIN DSPPAFENDK
IILYIAENSP IGSTVGEIYA HDPDEGPNAV VQYSIIGGED SNSFSLNVRQ GADRAELITL
EELDYESPKK KFELVVRAAS PPLRSDAVVQ ILVTDVNDNA PVLKDFQIIF NNFKDFFPTI
PIGRIPAVDA DVTDNLVYSI LAGNNANLID LNRTSGEIRL SPQLNTNVPR VATMEVAVTD
GINEAKATMT LSVRLITDEM LLNSITVRLD DMTVEAFLSP LLGYFLDGLA AIIPCPRENI
FLFSVQEDAN VQGKILNVSF SARKVEPGTV DEFYSPQFLQ ERVYLNRGIL ARLATVTVLP
FDDNLCVREP CLNFEECLTV LKFGNASGFA SSDTVLFRPI YPVTTFACRC ARGFTGSREA
YMCDTEVNLC YSNPCMNGGI CHRREGGYSC TCQPDFTGVN CEISMNRDAC SPGICKGDSQ
CTVKNTAGFT CEGCPVSALE SVTPFCELKA RSFGPATFLT FASLKQRHRF HLRLKFATEL
ADGLLLYNGR YNERHDFIAL EIVDSRVQFS FSLGNEVTRA MATVPGGVSD GQWHEVVVSY
INRTVTVSLD DCDVALALKH GEKRLGPKWT CAGRSERVLE ERCGLVTETC HRFLDLTGPL
QLGGLPAIPS SFQIRNKDYV GCISDLYIDH VFVDLNSFVA DNGTNAGCPE KAAFCASSPC
RNNGKCREIW SGFVCECEHN FAGPICAEEI GAPYSFHSNG MLGFNPLLRP IQLPWTTALS
FRTRAQLAFV MSVQIGQNSS VLLEIRNGKL VASLDGADVI RSGCTVADGE WHRMEIVWQS
GHVSLDTDYR ERPVTVPLPA KLQGLYVGRI LVGGPDQATN IDLPFFDGCL QDIRIGTNQS
VLQRPTIQEN VDAGCPSETY CNTECPQASI CIAQWRSSEC VCAAGHVGSN CERICNLEPC
SDAGTCIEDT SDLRRGYQCK CVSSDISGEY CETKSEQPCP ATWWGSPICG PCHCDETKGY
DPACNKTTGE CHCKENHYQP NGRKECIPCE CYTTGSFGPR CDSETGQCRC RTGVIGRSCT
DCPNSYAEVT LRGCEVVYDG CPRSYSDGLW WPRTLFGLTA IEDCPGTAEG KTSRSCDDKL
GGWQPPDLFN CTSEAFIEHR YQLAALETKD LTLNTYVAVK MAKDVYRAVN ITREMYGADL
LVTESLLVAL LRYEESLVGL NLTHSQDKDY VAHLIGIAGA ILRSKYKEKW DKIGELNGDS
PDKILDAMAR YLKTLTASQH DTFTNPFEVV NDNVVLGLDI VTSESLFGYE TIEYKEDPTV
STARPVEADR KVILPDTSAF LSSSAHFGPS ISFPKYNNYM ADPSRFDPHS KIQVPLNTLG
IKPVIQGELN VKNSLNNRKA VLSYVQYKEL GALLPQRFDD SVSVRWGVEV AVGSPVMTIS
VLVPSDNGYE SLTGIPLQSP IQVRLWLHEN DDFKTRTNPQ CVHWSTARGS GEWSRMGCTT
EIEDNSLSFG TIVNCSCMKL STFAILTDVL DLEYVPEPSL LEDVTSYSAF MLALPLLLSA
LLILALIRGG GTNSNSIHKN LVLCVFMAEI LYLIALKARN PLVSNEFPCK LTAIGLHYAW
LSTFAWTLVD SVHLYRMLTE MRDVNHGQMR FYYTMGYGLP AVIVGLTIGV RADQYGNFYF
CWLSIYETVI WSLIGPVCAA VLVNFCILVM CIRAAFTLKE HIMGFGNLRT LLWLSVASLP
LLGSTWTLAV LNASENSPML SYLLSVAIVV HAAFSLIGYC FINSRVRRNL YQSLLRCIGK
KTPLLEGSMG NGSSSQNVNG HSRSALAYSS TYNGAESVCK RVHVGVSTSS TTSRSTNKTG
SSPYRSDTHL RHTSTSTSNY NSDRDPYLSS RSHRSALHSR QESTEVRGQR RESESDSDGS
QAEGGGRSLD LASSHSSDED DVTSRSHRNM GVSTQQHVAH NYLPNIHTNP AEHLNILCSN
AELFPNIKPI YAPRWSSQLP EAYLSSNVMD VRSSQWSGGT MSDNEIASNK TSSPNPLPYP
EMNSPQKNQP DENYSEGEEK MHHLGEKYLF PYTAEEDHTV SPTPYMLSMS SRILASSMSH
HSQNSNHENL SGSEQRYGSL KRGQSLHGSQ HDNLSGSERY GSLKRGKMVT PTVLEDRPEY
ILPMSGRILS SSLTHDLQHS NELAALRQQQ QQQQQYEQTI TETE
//
