ID   A0A195E0R8_9HYME        Unreviewed;      1109 AA.
AC   A0A195E0R8;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   24-JAN-2024, entry version 22.
DE   SubName: Full=Nonsense-mediated mRNA decay protein 2 {ECO:0000313|EMBL:KYN18474.1};
GN   ORFNames=ALC57_09154 {ECO:0000313|EMBL:KYN18474.1};
OS   Trachymyrmex cornetzi.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC   Formicidae; Myrmicinae; Trachymyrmex.
OX   NCBI_TaxID=471704 {ECO:0000313|EMBL:KYN18474.1, ECO:0000313|Proteomes:UP000078492};
RN   [1] {ECO:0000313|EMBL:KYN18474.1, ECO:0000313|Proteomes:UP000078492}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tcor2-1 {ECO:0000313|EMBL:KYN18474.1};
RC   TISSUE=Whole body {ECO:0000313|EMBL:KYN18474.1};
RA   Nygaard S., Hu H., Boomsma J., Zhang G.;
RT   "Trachymyrmex cornetzi WGS genome.";
RL   Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR   EMBL; KQ979955; KYN18474.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A195E0R8; -.
DR   STRING; 471704.A0A195E0R8; -.
DR   Proteomes; UP000078492; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:InterPro.
DR   Gene3D; 1.25.40.180; -; 3.
DR   Gene3D; 4.10.80.160; -; 1.
DR   Gene3D; 6.10.250.770; -; 1.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR003890; MIF4G-like_typ-3.
DR   InterPro; IPR039762; Nmd2/UPF2.
DR   InterPro; IPR007193; Upf2/Nmd2_C.
DR   PANTHER; PTHR12839; NONSENSE-MEDIATED MRNA DECAY PROTEIN 2 UP-FRAMESHIFT SUPPRESSOR 2; 1.
DR   PANTHER; PTHR12839:SF7; REGULATOR OF NONSENSE TRANSCRIPTS 2; 1.
DR   Pfam; PF02854; MIF4G; 3.
DR   Pfam; PF04050; Upf2; 1.
DR   SMART; SM00543; MIF4G; 3.
DR   SUPFAM; SSF48371; ARM repeat; 3.
PE   4: Predicted;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Reference proteome {ECO:0000313|Proteomes:UP000078492}.
FT   DOMAIN          70..266
FT                   /note="MIF4G"
FT                   /evidence="ECO:0000259|SMART:SM00543"
FT   DOMAIN          440..629
FT                   /note="MIF4G"
FT                   /evidence="ECO:0000259|SMART:SM00543"
FT   DOMAIN          645..859
FT                   /note="MIF4G"
FT                   /evidence="ECO:0000259|SMART:SM00543"
FT   REGION          1..26
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1062..1109
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        12..26
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1109 AA;  127638 MW;  BBDB4BDC1E0C1F51 CRC64;
     MSENANEAAP AEKETLAEEP DAISEKDRQF LTEYVRETEQ RLATKEEIRA ANLNPARPPD
     ASFSKLDSSL KKNTTFVKKL KNFSMAQLDT VLKDMATLNL TKYVSEVATA LVDAKIKMID
     VAPAIRVCSF LHQTYAEFST HFFENWQRIL SLKVGDKITN PSKLRVDLRF YAELVNAGIF
     THKQGLPLLG SVLTVLINMD KEEHNNASII LSFCRHCGED YAGLVPKRVR ELSEKLNVSI
     PKSKMLSPDK QQNVKLLLRE YYNSLCKHML KEHKELQAFE KQNRKILQTR GELSSERKEK
     FEALQVCYER LLTNVQSFSD TLDEPMPELP VDNEIKAEVE ETLKMINEGE DNAMLEDMWG
     DEETRRFYEV FPDLTVFLPG SYLKDTPKDI PKTDTVITED ALDEEIVFDE LEETEKVEEP
     LEVEVEEPQI SNTSNKILLD AFLTHLPNCV NREMIDNAAV NFLMNLNTKH NKKKLVKALF
     GVSRIRQDLL PFYSRLAAIL YPVMPEIGND LCQMLKQDFK YHVRKKDQIN IESKIKVVRY
     IGELVKFKLY SKIEALYCLK VLLHDFTHHH IEMACNLLEI CGRYLFCSPD SHQRTKVYLE
     QMMRKKAVTA LDSRYVTIIE NAYYFVNPPE STGGVTKKDR PPVHEFIRKL LYQDLSKTNT
     DKVLKWMRKL DWEDDSVSSY AIKCLTAAYN VKYPNIRCVG SLLAGLVAHY ETIGPQVVDG
     VLEDIRLCME INLPKFNQRR IAMVKYLGEL YNYRMVESGD IFRTLYLLIT FGVSVDHSLQ
     SVLDPPDHLF RIRLVCTLLE TCGQYFSGGS SKKKLDYFLV FFQNYFWFKY TDPVWTSENP
     FPVGIDYMYR DTLTMLRPKM QLFQNYKEAQ CAVEELRNTL YPTLGNPPVD DATAEGENDM
     GVILEGDEEA ALGGNGSGDA KEGGTEGVIV DVTEELNAAL PSGPRRVSCP EDDDFLSALD
     KMVSDNIQDR MRDSVKQQQV DISVPLHVKS TKKTYEQLQE RPTDNSTVDF VLMLRKGNKQ
     QYKNLAVPVS SELAMNLRNR EQEQKEEKER VKRLTLNITE RQEEEDYQET MNQSTRPVTV
     NLNRERRQKY NHPKGAPDAD LIFGPKKIR
//