ID   A0A195EL55_9HYME        Unreviewed;      1400 AA.
AC   A0A195EL55;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   22-FEB-2023, entry version 26.
DE   SubName: Full=Calcium-dependent secretion activator {ECO:0000313|EMBL:KYN28990.1};
GN   ORFNames=ALC57_01637 {ECO:0000313|EMBL:KYN28990.1};
OS   Trachymyrmex cornetzi.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC   Formicidae; Myrmicinae; Trachymyrmex.
OX   NCBI_TaxID=471704 {ECO:0000313|EMBL:KYN28990.1, ECO:0000313|Proteomes:UP000078492};
RN   [1] {ECO:0000313|EMBL:KYN28990.1, ECO:0000313|Proteomes:UP000078492}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tcor2-1 {ECO:0000313|EMBL:KYN28990.1};
RC   TISSUE=Whole body {ECO:0000313|EMBL:KYN28990.1};
RA   Nygaard S., Hu H., Boomsma J., Zhang G.;
RT   "Trachymyrmex cornetzi WGS genome.";
RL   Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KQ978730; KYN28990.1; -; Genomic_DNA.
DR   RefSeq; XP_018373180.1; XM_018517678.1.
DR   RefSeq; XP_018373188.1; XM_018517686.1.
DR   RefSeq; XP_018373197.1; XM_018517695.1.
DR   STRING; 471704.A0A195EL55; -.
DR   GeneID; 108767692; -.
DR   OrthoDB; 5399598at2759; -.
DR   Proteomes; UP000078492; Unassembled WGS sequence.
DR   GO; GO:0031410; C:cytoplasmic vesicle; IEA:UniProtKB-KW.
DR   GO; GO:0098793; C:presynapse; IEA:GOC.
DR   GO; GO:1990504; P:dense core granule exocytosis; IEA:InterPro.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0016079; P:synaptic vesicle exocytosis; IEA:InterPro.
DR   CDD; cd01234; PH_CADPS; 1.
DR   Gene3D; 1.10.357.50; -; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR000008; C2_dom.
DR   InterPro; IPR033227; CAPS.
DR   InterPro; IPR010439; MUN_dom.
DR   InterPro; IPR014770; Munc13_1.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR001849; PH_domain.
DR   PANTHER; PTHR12166; CALCIUM-DEPENDENT SECRETION ACTIVATOR; 1.
DR   PANTHER; PTHR12166:SF8; CALCIUM-DEPENDENT SECRETION ACTIVATOR; 1.
DR   Pfam; PF06292; MUN; 1.
DR   Pfam; PF00169; PH; 1.
DR   SMART; SM01145; DUF1041; 1.
DR   SMART; SM00233; PH; 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   PROSITE; PS50004; C2; 1.
DR   PROSITE; PS51258; MHD1; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
PE   4: Predicted;
KW   Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329};
KW   Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW   Reference proteome {ECO:0000313|Proteomes:UP000078492};
KW   Transport {ECO:0000256|ARBA:ARBA00022927}.
FT   DOMAIN          440..554
FT                   /note="C2"
FT                   /evidence="ECO:0000259|PROSITE:PS50004"
FT   DOMAIN          580..690
FT                   /note="PH"
FT                   /evidence="ECO:0000259|PROSITE:PS50003"
FT   DOMAIN          980..1111
FT                   /note="MHD1"
FT                   /evidence="ECO:0000259|PROSITE:PS51258"
FT   REGION          1..155
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          426..445
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        50..92
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        103..139
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        140..155
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1400 AA;  157901 MW;  DD29D9FA0E5121CC CRC64;
     MIDPSSSEEE SEEDQSTHHG SGGGGSGGGR AGSGSSHGSR RHPGSIGNGP GSGSVGSLAS
     SLTASPGGPN HVGAPSTTST HGSGSRATTG PQETAGAGLD VPNLTSARNS LSPSMSAAQD
     ASNYAQRPTS PSPSVASEKT EAELQDKQER EEEQRKTRIQ LYVFISRCIA YPFNAKQPMD
     MTRRPMKVTK QQLETICSRF QSFLKGETQI MADEAFHNAI QNYYDVFLKS DRVVQMVQSG
     GCSQSDFREV FKKNIEKRVR SLPEIDGLSK ETVLTSWLAK FDCILKGTGD EDTKRPSRMQ
     QQSLNSELIL SKEQLYDMFQ QILGIKKFEH QLLFNALLLD SADEQAAAIR RELDGRVQKV
     NEMEKNRKLL PRFLLKEMES LYIEEQKVSI NLLMTNLESL PVSKGSIDSK YGLQKLKRYN
     HRGERSRCRG QGSLAKLEGD SADSDPQLTK MDVGLTFQLE VVVMEVKGLK SLAPDRIVYC
     TMEVEGGEKL QTDQAEASKP MWDTQGDFTT MHPLPVVKVR LYTENPAMLA LDDKELGKVI
     LRPTPLSCKV PEWHRMNVPK NCADQDLRMK IACRMDKPLN MKHCGYLYAM GKSVWKKWKK
     RYFVLVQVSQ YTFAMCSYKE KKSEPSEMMQ LDGYTVDYIE AVSANLMVGM DLEGGRYFFN
     AVREGDNIVY ASDDENECHL WVMAMYRATG QSHKPTPPVS VVDKNSTISK IQGDADRAKK
     HGMEDYISAD PCKFDHPGLF KYLQNSMLDY RLNDPYCSLG WFSPGQVFVL DEYCARYGVS
     GCFRHLYYLH DLLDRIDRGL MIDPTLMHYS FAFCASHVYG NTTSTDRVTS ITHEEKDKFL
     EIKERLRQIL ENQITNFRYS FPFGRPEGSL KAALSLLERV LMKDSVTPVP QEEVKALIKN
     CLETAALVNY TKLSAEAKIE DDLSGEVCVP PSKKLEDLIH LAELCVDLLQ QNEEHYSEAF
     AWFSDLMVEH AEIFWSLFAV DMDKVLAEQP PDTWDSFPLF QIMNDYLKTD DNLKNGRFHQ
     HLRDTFAPLV VRYVDLMETS IAQSIHKGFE KERWEIKGNG CATSEDLFWK LDALQSFIGG
     LHWPDQEFRQ HLEQRLKLMA CDMVESCIQR TDAAFQQWLK KGVTFISTDY IIPSEMCAMV
     NVILDAKNQS FKLCTVDGVD VHQYHSKIDD MIEKTSAGMN QGMINKLITV LEATLSKLSR
     YDEGSLIGSI LSLTKVSGSG KEMGQAYVNF MRNCIDQIRS KVLDELWILT FFEQWYTAQI
     QMLCNWLSER LDHSLHLYQC TCLAHIVKKI YSDFELQGVM EEKLNTKTYQ TIDKRMKTEE
     ATCALTMSAQ NEEGLSENGN DDEVERPKTK VTIVETITED ANYVANLSNV TSNVVGKVGS
     MFGKGIGGLS TKFGSASNWF
//