ID A0A195EQY7_9HYME Unreviewed; 836 AA.
AC A0A195EQY7;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN ORFNames=ALC56_15282 {ECO:0000313|EMBL:KYN30586.1};
OS Trachymyrmex septentrionalis.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Myrmicinae; Trachymyrmex.
OX NCBI_TaxID=34720 {ECO:0000313|EMBL:KYN30586.1, ECO:0000313|Proteomes:UP000078541};
RN [1] {ECO:0000313|EMBL:KYN30586.1, ECO:0000313|Proteomes:UP000078541}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tsep2-gDNA-1 {ECO:0000313|EMBL:KYN30586.1};
RC TISSUE=Whole body {ECO:0000313|EMBL:KYN30586.1};
RA Nygaard S., Hu H., Boomsma J., Zhang G.;
RT "Trachymyrmex septentrionalis WGS genome.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SIMILARITY: Belongs to the protein kinase superfamily. TKL Ser/Thr
CC protein kinase family. RAF subfamily. {ECO:0000256|ARBA:ARBA00010507}.
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DR EMBL; KQ982021; KYN30586.1; -; Genomic_DNA.
DR RefSeq; XP_018355366.1; XM_018499864.1.
DR AlphaFoldDB; A0A195EQY7; -.
DR STRING; 34720.A0A195EQY7; -.
DR GeneID; 108756232; -.
DR OrthoDB; 4560496at2759; -.
DR Proteomes; UP000078541; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd20811; C1_Raf; 1.
DR CDD; cd01816; RBD_RAF; 1.
DR Gene3D; 3.30.60.20; -; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR046349; C1-like_sf.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR002219; PE/DAG-bd.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR003116; RBD_dom.
DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR23257:SF954; PROTEIN KINASE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR23257; SERINE-THREONINE PROTEIN KINASE; 1.
DR Pfam; PF07714; PK_Tyr_Ser-Thr; 2.
DR Pfam; PF02196; RBD; 1.
DR SMART; SM00109; C1; 1.
DR SMART; SM00455; RBD; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF57889; Cysteine-rich domain; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
DR PROSITE; PS50898; RBD; 1.
DR PROSITE; PS00479; ZF_DAG_PE_1; 1.
DR PROSITE; PS50081; ZF_DAG_PE_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:KYN30586.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000078541};
KW Serine/threonine-protein kinase {ECO:0000256|ARBA:ARBA00022527};
KW Transferase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:KYN30586.1};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 209..280
FT /note="RBD"
FT /evidence="ECO:0000259|PROSITE:PS50898"
FT DOMAIN 290..335
FT /note="Phorbol-ester/DAG-type"
FT /evidence="ECO:0000259|PROSITE:PS50081"
FT DOMAIN 446..767
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 400..428
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 592..654
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 175..212
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 620..654
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 836 AA; 97392 MW; 022F23EA4A9AF374 CRC64;
MSRKTWYAKQ LKMAYKRRMQ MIESDELYNS LEIEESTVPL TAANMMIEPD KFDNLEIAIP
STSTTSYPLS RSTMLHRELQ DAIQNKDRMN ECNGYEDSQQ IVESVPSTST AIHSDSYQSL
IQEKKSLKFE IDNIGKVMTC CKTAVNRWLS VLDEEFPEKE YLQEYEEGAD KLHELQCIEI
ELENKQEKIE ELEKLRKKAE EAKKKKKISI LMIHLPNSQY TTIEVKEGLT LRNAVSKAME
RRQLILDDCA AYIKQRMTYF ISWDTDISTL PCKEVFVEYL ETFPVPVFWT HNFAGTKVLL
GYCYVCGKSV LYGFICKACN RKFHTKCVSY ASLLCEHIRR RTAYYERLLA NNPTTGIIQI
PPVPVPSISS RRRIKKPAQD IEPTTIDKTT QVTTRTKFLR YPRRNKRHQK SKDQDDSCAD
DTESEDSIFS QDSIRDFKIV AEEVTYEDDD EKGKGTYGTV YKADWYGPVA VKRLNIEVPT
ELEIEMFKNE VNVLRKIRHM HVLSFMACIV KPYLAIITQW CEGNSLYHRL HVAEDELEMI
TIVIILKQIS EGMDYLHARN IHHRDLKSKN IFFHNGLHVK IGDFGLAVMK SRQPRNNRRD
ELDEKDERDE RDENDENDEK DEEIKKGKKN KKVGTDDKIK KTKRTTTKSK KELEEELENQ
LAGSVRWMAP EVLRFKEDYP YSFQSDVYAF GIVMYELFAR DLPYGYKTDK LFILYNVGRG
GLKPDDKKIR SDTPKKLVKL YNQCIEFEKE KRPLFPYILR QVYHVFKATP KIRRTTSLPL
KTDVLADTYI ERADDVQDFL TSDADDYDDE KAIDANINAN VSVSNSASVV DVFADF
//
