ID A0A195FA56_9HYME Unreviewed; 2109 AA.
AC A0A195FA56;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=DNA polymerase zeta catalytic subunit {ECO:0000256|ARBA:ARBA00021589};
DE EC=2.7.7.7 {ECO:0000256|ARBA:ARBA00012417};
GN ORFNames=ALC56_08720 {ECO:0000313|EMBL:KYN36929.1};
OS Trachymyrmex septentrionalis.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Myrmicinae; Trachymyrmex.
OX NCBI_TaxID=34720 {ECO:0000313|EMBL:KYN36929.1, ECO:0000313|Proteomes:UP000078541};
RN [1] {ECO:0000313|EMBL:KYN36929.1, ECO:0000313|Proteomes:UP000078541}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tsep2-gDNA-1 {ECO:0000313|EMBL:KYN36929.1};
RC TISSUE=Whole body {ECO:0000313|EMBL:KYN36929.1};
RA Nygaard S., Hu H., Boomsma J., Zhang G.;
RT "Trachymyrmex septentrionalis WGS genome.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- SIMILARITY: Belongs to the DNA polymerase type-B family.
CC {ECO:0000256|ARBA:ARBA00005755}.
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DR EMBL; KQ981727; KYN36929.1; -; Genomic_DNA.
DR STRING; 34720.A0A195FA56; -.
DR Proteomes; UP000078541; Unassembled WGS sequence.
DR GO; GO:0016035; C:zeta DNA polymerase complex; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR GO; GO:0019985; P:translesion synthesis; IEA:InterPro.
DR CDD; cd05778; DNA_polB_zeta_exo; 1.
DR CDD; cd05534; POLBc_zeta; 1.
DR Gene3D; 1.10.132.60; DNA polymerase family B, C-terminal domain; 1.
DR Gene3D; 3.30.342.10; DNA Polymerase, chain B, domain 1; 1.
DR Gene3D; 1.10.287.690; Helix hairpin bin; 1.
DR Gene3D; 3.90.1600.10; Palm domain of DNA polymerase; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR006172; DNA-dir_DNA_pol_B.
DR InterPro; IPR017964; DNA-dir_DNA_pol_B_CS.
DR InterPro; IPR006133; DNA-dir_DNA_pol_B_exonuc.
DR InterPro; IPR006134; DNA-dir_DNA_pol_B_multi_dom.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR042087; DNA_pol_B_thumb.
DR InterPro; IPR023211; DNA_pol_palm_dom_sf.
DR InterPro; IPR030559; PolZ_Rev3.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR025687; Znf-C4pol.
DR PANTHER; PTHR45812; DNA POLYMERASE ZETA CATALYTIC SUBUNIT; 1.
DR PANTHER; PTHR45812:SF1; DNA POLYMERASE ZETA CATALYTIC SUBUNIT; 1.
DR Pfam; PF00136; DNA_pol_B; 1.
DR Pfam; PF03104; DNA_pol_B_exo1; 2.
DR Pfam; PF14260; zf-C4pol; 1.
DR PRINTS; PR00106; DNAPOLB.
DR SMART; SM00486; POLBc; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS00116; DNA_POLYMERASE_B; 1.
PE 3: Inferred from homology;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00022932};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW Reference proteome {ECO:0000313|Proteomes:UP000078541};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 95..206
FT /note="DNA-directed DNA polymerase family B exonuclease"
FT /evidence="ECO:0000259|Pfam:PF03104"
FT DOMAIN 1243..1448
FT /note="DNA-directed DNA polymerase family B exonuclease"
FT /evidence="ECO:0000259|Pfam:PF03104"
FT DOMAIN 1514..1964
FT /note="DNA-directed DNA polymerase family B
FT multifunctional"
FT /evidence="ECO:0000259|Pfam:PF00136"
FT DOMAIN 2007..2073
FT /note="C4-type zinc-finger of DNA polymerase delta"
FT /evidence="ECO:0000259|Pfam:PF14260"
FT REGION 757..861
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 763..781
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 790..861
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2109 AA; 240788 MW; 1EAF34ED9242AB8F CRC64;
MFSITLVNID SYQASPIPEL DVTFSEFRGS EIKKVPIIRA FGSTATGKKT CLHIHGIFPY
LYVPCTVQGN TDSYAYQLAA AIDSALNTSF GSTLSTNQHV YKIQRVSGIP FYGYHEKEHM
FFKIYFYNPA IIKRTADLLQ NGVVLNQTLQ PYEAHIPYIL QFMIDYNLYG MNLINLNSVK
YRHSLQGCAT EDSQSRSSMD FLDSKAYLPI SITRQSMCEL EVDVHASEIL NRQSVNEKLE
LNPGLAAIWN EEKTRRAEAS LENAKSQLLY PKTPSKIILP PTRNDVYQKD QLLKRLNAIS
QTNETITSNT MISSYPIEVE SNENVLNASH ILNHSESLVS EENLERIISD NCKLLQLASS
AFLDATRSQS NMTDTSFLDA DDIQLVDMLV DLAEENEIAS NVDDDSVLGS QYSMFNERIK
DDPDEEEVED LNITSFDLDL SSWESVYNQK SNQHDNTVKV IDNKQNIESA DDSNVTEEND
GDVTLVNFPQ VDGVDDLYEI VSKHEKTLNS LSNKNNIACC MAVQCLPKII TKNSRNNCVS
VINTRKDYAM RTLYRNFNLM DIIKYINVNN PNRYYLRKEL YNFVNRYYFH IFFKTSKHLR
GMTVKYPHTD ISFVARKNRY LKDNGKRIAH SKKTEEELYV TRWQLQLDHR DLDVYDIDEI
ETFDTMEHVN YITNSKEKCN CEQEFKSCIQ EEGLLNSNHC FYHELYDFSV NFTISNVDGA
TADSSDAESE ADVTIEKQEE RVCTYKSDKK NIPQNIVQIT PKKRKFDSQD DDHESSNKRK
NVAKTPKRKY NSPGKTSRSP QLSGNYSPLN ITITSPKSNK GLVRQCESPK RNQYVPTPDI
PSTSTTPKHK KQNNGTDNDT YNEIDTVNIA KIDKTTIYES IQDHQKGTES SEKSFIKTNK
EVRKRLSFLN YDEEDTFVKS DHNKNQSETL IALGHSSNQV HAEATTLISS NANSDDSVPN
SQCTEKSIND VSPERNYASD IQNLAKKFIK IHSDVIPETD LDDDEDVCNI TFTQHLNQKI
ESDSQSSMSE QRVRRSSKNA IITITTKYKP PSPGRILESM TMYGIPKCRS QKPFFSNKLD
LAKQKEFLNT NASYFDEPAF KSSLEEITSI KLWRRMKVNE FYPSGASIKS YHIKRTLAGY
NSLTIKPLIE PPSSKNVRDW IRAKKYISKK NSDAKSYSPM PQQSMLNKTF DETRKLEIQN
SNDSLISEKS LDPSLKRALA NPLLHKQHKT QLGVSYGQIE CSSKGSYESN VSNENLQKAR
AVTVHQYLTL LSLEVHAVTR EDLLPDPQYD SIAALFYAIY NDAPTDATTD EQIEHAAIIV
NSNSISARLN KIHSASARCP ILYVATEQDA FNSLVKLIER HNPDILLGWE VEVLSWGYIF
QRAFHLGLHN FPLKISKIPH MQIYSKSDAH AIEKDDIGDV KVSGRNLLDV WRIMRHEAAL
LTYTFENVMH HVLHERVPCP SFKTLSTWWK QESMIIKSRV IHHYIVRVVG TLKLLGHLDV
IGRTCELARL FGIQFYEVFS RGSQFRVESM MLRLAKPMNY IPISPSMHQR AKMRAPECLP
LIMEPESKFY TDPLIVLDFQ SLYPSMIIAY NYCFSTCLGR IEHIGQYGPF EFGAATLRVR
KNTALKLQDK INFSPCGVAF VKKEVRQGIL PRMLSEILNT RLMVKESMKL HPAENRTLQR
VLHSQQLGLK LIANVTYGYT SANFSGRMPC IEIGDSVVSK GRETLERAIK LVETTPRWGA
RVVYGDTDSL FILLPGKSRE EAFTIGEEIA DAVTATNPPP VKLKFEKVLH PSILQTKKRY
CGYMYETRNQ EKPEFLAKGI ETVRRDGCPA VSKILEKALK ILFETKDVSL VKQYVMRQFD
KIFQRRVSIL DLTFAKEFRG MRGYKANACV PALELTRRLI KKDPRAVPRT SERVRYVIVA
GAPNQALIHC VRTPMEVVAD PSLMPNSVYY ITKVIIPPLN RCFNLFRIDV NTWYKEVSHR
SNFDNIAHLG GDNPKSTIRQ FFSCASCITC GEQTNKEICP DCLLQPNRTV LVLLEKIKQL
ERNHQQITAI CHSCIRRLGN IECMSLDCPV LYRMAQAHKE LAQVTYLNSI IYGNNSSGIK
ELNAVAEWY
//
