ID A0A195FDY4_9HYME Unreviewed; 3668 AA.
AC A0A195FDY4;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Laminin subunit alpha {ECO:0000313|EMBL:KYN38880.1};
GN ORFNames=ALC56_06879 {ECO:0000313|EMBL:KYN38880.1};
OS Trachymyrmex septentrionalis.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Myrmicinae; Trachymyrmex.
OX NCBI_TaxID=34720 {ECO:0000313|EMBL:KYN38880.1, ECO:0000313|Proteomes:UP000078541};
RN [1] {ECO:0000313|EMBL:KYN38880.1, ECO:0000313|Proteomes:UP000078541}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tsep2-gDNA-1 {ECO:0000313|EMBL:KYN38880.1};
RC TISSUE=Whole body {ECO:0000313|EMBL:KYN38880.1};
RA Nygaard S., Hu H., Boomsma J., Zhang G.;
RT "Trachymyrmex septentrionalis WGS genome.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004370}.
CC Secreted, extracellular space, extracellular matrix, basement membrane
CC {ECO:0000256|ARBA:ARBA00004302}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00460}.
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DR EMBL; KQ981636; KYN38880.1; -; Genomic_DNA.
DR STRING; 34720.A0A195FDY4; -.
DR Proteomes; UP000078541; Unassembled WGS sequence.
DR GO; GO:0005604; C:basement membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005102; F:signaling receptor binding; IEA:InterPro.
DR GO; GO:0048513; P:animal organ development; IEA:UniProt.
DR GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR GO; GO:0016043; P:cellular component organization; IEA:UniProt.
DR GO; GO:0030155; P:regulation of cell adhesion; IEA:InterPro.
DR GO; GO:0030334; P:regulation of cell migration; IEA:InterPro.
DR GO; GO:0045995; P:regulation of embryonic development; IEA:InterPro.
DR GO; GO:0048731; P:system development; IEA:UniProt.
DR CDD; cd02795; CBM6-CBM35-CBM36_like; 1.
DR CDD; cd00055; EGF_Lam; 22.
DR CDD; cd00110; LamG; 5.
DR Gene3D; 2.60.120.200; -; 5.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 2.10.25.10; Laminin; 21.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR009254; Laminin_aI.
DR InterPro; IPR010307; Laminin_dom_II.
DR InterPro; IPR001791; Laminin_G.
DR InterPro; IPR000034; Laminin_IV.
DR InterPro; IPR008211; Laminin_N.
DR InterPro; IPR002049; LE_dom.
DR PANTHER; PTHR10574:SF365; NETRIN-A-RELATED; 1.
DR PANTHER; PTHR10574; NETRIN/LAMININ-RELATED; 1.
DR Pfam; PF00052; Laminin_B; 1.
DR Pfam; PF00053; Laminin_EGF; 21.
DR Pfam; PF02210; Laminin_G_2; 5.
DR Pfam; PF06008; Laminin_I; 1.
DR Pfam; PF06009; Laminin_II; 1.
DR Pfam; PF00055; Laminin_N; 1.
DR PRINTS; PR00011; EGFLAMININ.
DR SMART; SM00181; EGF; 10.
DR SMART; SM00180; EGF_Lam; 22.
DR SMART; SM00281; LamB; 1.
DR SMART; SM00282; LamG; 5.
DR SMART; SM00136; LamNT; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 5.
DR SUPFAM; SSF57196; EGF/Laminin; 22.
DR PROSITE; PS01248; EGF_LAM_1; 7.
DR PROSITE; PS50027; EGF_LAM_2; 15.
DR PROSITE; PS50025; LAM_G_DOMAIN; 5.
DR PROSITE; PS51115; LAMININ_IVA; 1.
DR PROSITE; PS51117; LAMININ_NTER; 1.
PE 4: Predicted;
KW Basement membrane {ECO:0000256|ARBA:ARBA00022869};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00460}; Extracellular matrix {ECO:0000256|ARBA:ARBA00022530};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Laminin EGF-like domain {ECO:0000256|ARBA:ARBA00023292,
KW ECO:0000256|PROSITE-ProRule:PRU00460};
KW Reference proteome {ECO:0000313|Proteomes:UP000078541};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022530};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..3668
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5008271373"
FT DOMAIN 18..269
FT /note="Laminin N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51117"
FT DOMAIN 444..489
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 490..535
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 536..581
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 582..626
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 627..676
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 727..779
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 1361..1406
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 1407..1449
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 1450..1497
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 1498..1548
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 1568..1750
FT /note="Laminin IV type A"
FT /evidence="ECO:0000259|PROSITE:PS51115"
FT DOMAIN 1784..1833
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 1892..1944
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 1945..1991
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 1992..2038
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 2039..2086
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 2646..2838
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 2849..3023
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 3030..3200
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 3311..3482
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 3488..3665
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT COILED 2619..2646
FT /evidence="ECO:0000256|SAM:Coils"
FT DISULFID 444..456
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 446..463
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 465..474
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 490..502
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 492..509
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 511..520
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 536..548
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 538..555
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 557..566
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 582..594
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 602..611
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 627..639
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 647..656
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 750..759
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 1361..1373
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 1363..1380
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 1382..1391
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 1422..1431
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 1473..1482
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 1498..1510
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 1500..1517
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 1519..1528
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 1803..1812
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 1916..1925
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 1928..1942
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 1964..1973
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 2012..2021
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 2039..2051
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 2041..2058
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 2060..2069
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 3638..3665
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00122"
SQ SEQUENCE 3668 AA; 406828 MW; 19F16FDE2BB898C5 CRC64;
MQLPAIFAGL LLIIRLSRSE ILTPPYFNLA EGKEIVASAT CGVDTTGPEL YCKLVGANAD
QDEDINLIQG QVCDYCDPEN PEKSHPPEYA VDGMETWWQS PPLSRGMKYN EVNLTINLGQ
EFHVAYVYIR MGNSPRPGLW VLEKSKDYGK TWSPWQYFSD SASDCLTYFG VDSHKPITRD
DSVICTTEYS KVVPLEGGEI PISILNNRPS AKHYFNSTLL QEWTRATNVR FRFLRTKNLL
GHLMSVVRQD PTVTRRYFYS IKDISIGGRC MCNGHADTCD IQDPNMPKKL VCRCQHNTCG
PQCATCCKGF EQKKWRQSTA SQKFICEPCN CFGHSDECIY DPNIDEKHLS LDIHGNYEGG
GICQNCKHNT EGINCNRCKP KFYRPWDKPL NATDVCQPCN CDYFYSTGNC SDSTGKCECR
KEFTPPNCDT CNYGYFGYPN CLPCQCDLRG TDGYHCEATD GYCPCKLNYA GHYCNLCAEG
YYNFPDCLPC DCNPLSALDN VCDVISGNCT CKNNYGGRTC DICEDGYFNY PFCTYCNCDA
RGTEPGICDK TNGSCSCKEG YGGIRCDQCT PGYYGYPNCV PCNCSSVGSS SISCDSTGKC
SCLANFAGRT CSQCSPGYYK YPECVACSCD SHGSIGVSCD GEGKCQCREN FDGIRCEQCK
EGYYNFPTCE GCNCDPAGIV ATFQGCGSLP PGELCQCKER VEGRICNQCK PLYWNLQPYN
PDGCEECHCN IPGVIGSIGE CDTKTGQCIC KPGVTDRGCS RCIDGTYNLQ EDNLFGCSDC
SCDVGGSVNP ICDKQTGQCP CQPRITGLTC KEPLKAHYFP TLHQYQYEAE VGKTPSGSGV
PYGFAEDIFP GFSWKGYAEF TNQQKEIILG VGIGKSSLYR MVLRYVNPNN DPILGTITII
PDSPSEIEQQ FIVNFKPTTR PSFVTVAGAH GNHPLPMVMN PGHWSIKIST KRSMFLDYFV
LLPSEYYEGG ILTQDVNVPC EVGYKGLCRH YGYPNLTWFD SVHGAGGFLS ENNVRIPLTE
YFTDHETLQE INEDEVPLIN NQQEEIHFEL RISKPGPHVL VVTYVTPRDE QDTSVLLIEA
NTVGKGKVIL NPCRYTSTCR QVVTDTYGKV AVMNFPSNYV SLVLTGESTS NVAIDSIVAI
PYHQWSLDYI KPKSVCVRKN GKCIQGLFPD AADAKKIEFE TSNNILEAET RPPGIYDNAT
KLIYLSDGDM VDIHAKVSQP GDYIFVVQYY QPDHPQFELD VLVQNGKFYE AKVPVPHCPS
NSGCRSIIRQ IDNNDTRFQL IENFVLTLKE PGHGIWLDYI LVIPADQYNE KILSKLQFDE
TNEFIKRCGS NHFHINVTED GFCRDSTFSL TANYNNGALP CNCDGEGSTS FECEKFGGQC
PCRPNIIGRR CEICKSGFYG FPRCRPCNCP ALCERDTGRC ICPSRVTGQR CDQCEPGTYG
FHPIIGCEEC NCSPLGVLDG DLQCDLFDGS CRCKENVVGR QCDRCRAGYS QFPHCERCDC
DSRGTTADIC DQYTAECFCK ANVQGQACDV CREGTFNIQA ENTDGCTKCF CFGKTTRCAS
ANLYWTHLMD MAWELITPID KSGNFTTLST YPVENATAIT VSLIANDTFE NVIYFSAPDT
YLDKKLTSYG GYLNYSVYYS TGPFGKAVSA ADVILQGANI TLFYYSDEQP PSFVNFRASV
RLIEANFVTS NRLSATREQI MVVLEDLRGI YVRATYWNPS IMASLSYVTW DITTEQYSAQ
YSIPAGSVEQ CQCPPNYQGL SCEECAPGYY RIKSGPYGGY CAPCQCNGHA TACDVNTGIC
QNCKNGTTGD HCEFCEQGYY GNATVGTPTD CLICACPLPV ASNNFATGCE VNEEGNKISC
DCLPGYYGAR CEACAAGYYG NPEVYGDYCK PCECSGNIDT NQIGSCDSIT GQCLQCLNNT
YGEACNLCAP GYFGDAVERK DCRSCVCDDC GMEHCDSYSG QCFCRENVIG ERCDHCAPNH
YGFGTCNGCR PCDCDLASES SQCDGETGQC KCMPGVTGRR CDQCIQGYWN YGRDGCTSCE
CNTGYSVGVS CDTTTGQCTC LPGVIGEKCD HCPYRHVLIP SQGCFSCGSC TGNLLDVTDE
LADLVEPVSR EYSTVAEGYF TNQRLKFIND TVNELYPEVK LLDPNRVNLL PLQEKLKQLE
NEVYYQKQQI DFTAEDSGKW KDNAENTLQD MNTLEEDVVH KIDLVNQIVS EVQSLALNIE
LGTGAKVDNA LNEAKEILKK IKDVSFIEFR DNAVDQANQA NILISEMQQY SFPASNLSFA
VTDLNVRIKN ISVKMDDLLD TVKIAQDTAS IADKLNRENR IAAQSGNLDV VKNSTAEARE
DLEAGEQLKN NASDFLNHAK TNIDLLRINT DSDVIDQLNN TIALNDEMLI DLAEPVQKAQ
VHAAYLHNRS LELDSLLTDT RNTNAVRAVS AYRDIETAIQ AAKDAADNAI IAAENATSLT
DGIEQKMLDS RNECFKLLAA AQVALTKTTG QPENDLRDAR NNATLIDTQN KRNKELLDSI
DKTLGNIPSQ SSSVAHDAMN QAMNVESNIE IAIDDMNGIV NQIPEDLRET KQLSKNTSET
IREISQANKQ LDGVDKVMPS INSLLNSLNG NQKSIDATGN DLQSKIEALR NKIANARELA
NRFKTGLTFY RNTTLELKNP ESLPLLSTST KISLYFRTNK TNGFLLYLGN EEKSKLPRSK
AHDFTALLIE SGYPVLIVDL GSGPERINHN KFVSDNVWRQ IIIDRTGKNV KLIVREDIGE
GKDTLYEKER VLSGPYYIFN VDQEHSKLFV GGYPSSFHIQ DAVTASSFEG EMEELMIGDI
PVSFWNFVDG ENNQKSALER DKLINFAPSR GYRFDRHGYA ILSKKSSQIT PDTRKFIIKL
SFKTFVEDGL IYLMGKGRQF LSIEIRNGQL LYQYDLGEGT IVLRSLNKYN DGNWHTLEAI
RQDTMGALKI DDHTVASSQE RGTTKPLASS DHIYFGGYPP NAKRPYDSVT NNGFEGCIDD
VVILDTSVDL TRNVQAFGVM PGCPVRFASL VSFEKNTPGY VRWRNLASDG LQVNLKFKTL
ASNGLIFYAT NDELQNAATS YLSLVDGQLV FTSQGEELRT SPSDVKFNDN EWHVVTATHD
QSALSLDIDD MENYSTDSAP PPLHFLYGNL YIGGLPSNFD FGERKVVPFV GCIGDATLNS
EIIINFANTT ERPYAFLGKC KGSDQTLSPP VVKPEFLPPL LPSEGPEDTV ELSTQISKTE
TNYFLLDIIE VDVDKEDEKE EEEEEPELEG RNNVDKYDFT TTTQRPTEQP ETVDKCHLPY
YPATDPDLEN AWRFGTARNS RLEYRSLNGR YKDDYDFQID IKTMADDGII FYTSDLSKQN
LIAVYVLGGK VHYKFDCGSG PALLVSKKMI NNNQWHIIIF KRNGNYGHLT VDEEDVIGYS
LGNTTAINVN PPFFVGGILP EISSIAYTNI GLNKTFSGCL GNFMTNGQPV GEPSEKVGVI
PCSKRVEPGI FFYPGNGSNL FKAVDRFNVD RTVDIQMDIK PRSTSGHLLS VHGKRDYLVL
EMINGTVKFL IKTQRGSIET AFEPTKPNSL CDGHWHNIRA VKQKNAVLLS VDHKPAPPGI
GGKNVARVLS KHPIFIGGHP MLGKRLRGST SQAQYVGCIN NILINMKPVS IRPERAYGQV
ITGVCPTI
//
