ID A0A195FV54_9HYME Unreviewed; 394 AA.
AC A0A195FV54;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial {ECO:0000256|ARBA:ARBA00019998};
GN ORFNames=ALC56_01277 {ECO:0000313|EMBL:KYN44306.1};
OS Trachymyrmex septentrionalis.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Myrmicinae; Trachymyrmex.
OX NCBI_TaxID=34720 {ECO:0000313|EMBL:KYN44306.1, ECO:0000313|Proteomes:UP000078541};
RN [1] {ECO:0000313|EMBL:KYN44306.1, ECO:0000313|Proteomes:UP000078541}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tsep2-gDNA-1 {ECO:0000313|EMBL:KYN44306.1};
RC TISSUE=Whole body {ECO:0000313|EMBL:KYN44306.1};
RA Nygaard S., Hu H., Boomsma J., Zhang G.;
RT "Trachymyrmex septentrionalis WGS genome.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Mitochondrion {ECO:0000256|ARBA:ARBA00004173}. Nucleus
CC {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the ECSIT family.
CC {ECO:0000256|ARBA:ARBA00007674}.
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DR EMBL; KQ981241; KYN44306.1; -; Genomic_DNA.
DR RefSeq; XP_018352561.1; XM_018497059.1.
DR AlphaFoldDB; A0A195FV54; -.
DR STRING; 34720.A0A195FV54; -.
DR GeneID; 108754620; -.
DR OrthoDB; 4098911at2759; -.
DR Proteomes; UP000078541; Unassembled WGS sequence.
DR GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR InterPro; IPR029342; ECIST_C.
DR InterPro; IPR010418; ECSIT.
DR InterPro; IPR046448; ECSIT_N.
DR PANTHER; PTHR13113; ECSIT EVOLUTIONARILY CONSERVED SIGNALING INTERMEDIATE IN TOLL PATHWAYS; 1.
DR PANTHER; PTHR13113:SF1; EVOLUTIONARILY CONSERVED SIGNALING INTERMEDIATE IN TOLL PATHWAY, MITOCHONDRIAL; 1.
DR Pfam; PF14784; ECSIT_C; 1.
DR Pfam; PF06239; ECSIT_N; 1.
DR SMART; SM01284; ECSIT_Cterm; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Immunity {ECO:0000256|ARBA:ARBA00022859};
KW Innate immunity {ECO:0000256|ARBA:ARBA00022588};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000078541};
KW Transit peptide {ECO:0000256|ARBA:ARBA00022946}.
FT DOMAIN 246..364
FT /note="ECSIT C-terminal"
FT /evidence="ECO:0000259|SMART:SM01284"
SQ SEQUENCE 394 AA; 45847 MW; CC13D6AAA3A8D86A CRC64;
MFSRITRTIL ASNVTALLRQ SLREIEGRSL SRTIHTSQER CKKNDEKDSK PSTLVLHAFL
NAENKEREAY LDILREYKTN NEMRRGHVEF IQVALKYMDE FGVNRDLAVY KAVLDVLPKG
KFIPRNYFQT LFMHYPKQQH VAIDLLCKME HNSVIPDLEM QEMLLNIFGY QALVLKKFWR
MMYWMPKFAN LNPWPCPTPM PKDPKVLAKL AMNKISSADV QTELTEFKTK DVEDAIDDTW
IVSVMSSSQE ELLQKQPLNT PIFVEGPYTV WIKNHCIDYF ILKGAPKEKN NVYQNPDDVS
DIRIPFWDNK EIILPPTIHE QNDGTYFAMC ATGTSTKDSL LSWIRCLQEK NPVLTVIPVV
FKLMSSTREQ FYIDSGESEN NLVQKKDQQK DTNC
//
