ID A0A195FW64_9HYME Unreviewed; 620 AA.
AC A0A195FW64;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 13-SEP-2023, entry version 35.
DE SubName: Full=Rab GTPase-binding effector protein 1 {ECO:0000313|EMBL:KYN44900.1};
GN ORFNames=ALC56_00896 {ECO:0000313|EMBL:KYN44900.1};
OS Trachymyrmex septentrionalis.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Myrmicinae; Trachymyrmex.
OX NCBI_TaxID=34720 {ECO:0000313|EMBL:KYN44900.1, ECO:0000313|Proteomes:UP000078541};
RN [1] {ECO:0000313|EMBL:KYN44900.1, ECO:0000313|Proteomes:UP000078541}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tsep2-gDNA-1 {ECO:0000313|EMBL:KYN44900.1};
RC TISSUE=Whole body {ECO:0000313|EMBL:KYN44900.1};
RA Nygaard S., Hu H., Boomsma J., Zhang G.;
RT "Trachymyrmex septentrionalis WGS genome.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Early
CC endosome {ECO:0000256|ARBA:ARBA00004412}. Endosome
CC {ECO:0000256|ARBA:ARBA00004177}.
CC -!- SIMILARITY: Belongs to the rabaptin family.
CC {ECO:0000256|ARBA:ARBA00006603}.
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DR EMBL; KQ981208; KYN44900.1; -; Genomic_DNA.
DR RefSeq; XP_018346727.1; XM_018491225.1.
DR AlphaFoldDB; A0A195FW64; -.
DR STRING; 34720.A0A195FW64; -.
DR GeneID; 108751153; -.
DR OrthoDB; 2904642at2759; -.
DR Proteomes; UP000078541; Unassembled WGS sequence.
DR GO; GO:0005769; C:early endosome; IEA:UniProtKB-SubCell.
DR GO; GO:0008083; F:growth factor activity; IEA:InterPro.
DR GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR GO; GO:0060255; P:regulation of macromolecule metabolic process; IEA:UniProt.
DR CDD; cd15739; FYVE_RABE_unchar; 1.
DR Gene3D; 1.20.5.730; Single helix bin; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR003914; Rabaptin.
DR InterPro; IPR018514; Rabaptin_coiled-coil.
DR InterPro; IPR015390; Rabaptin_Rab5-bd_dom.
DR InterPro; IPR000306; Znf_FYVE.
DR InterPro; IPR017455; Znf_FYVE-rel.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR31179:SF7; FYVE-TYPE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR31179; RAB GTPASE-BINDING EFFECTOR PROTEIN; 1.
DR Pfam; PF01363; FYVE; 1.
DR Pfam; PF09311; Rab5-bind; 1.
DR Pfam; PF03528; Rabaptin; 2.
DR SMART; SM00064; FYVE; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR PROSITE; PS50178; ZF_FYVE; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Endocytosis {ECO:0000256|ARBA:ARBA00022583};
KW Endosome {ECO:0000256|ARBA:ARBA00022753};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000078541};
KW Transport {ECO:0000256|ARBA:ARBA00022448};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 546..604
FT /note="FYVE-type"
FT /evidence="ECO:0000259|PROSITE:PS50178"
FT DOMAIN 552..600
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 200..287
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 320..372
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 430..516
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 620 AA; 71891 MW; 1C0A8585BFE3C78F CRC64;
MENQDDRTVK ANGNEDPQAK ISRLESENVK MREEFNVQRA KMKELFLQKE EELKRRLEEN
MGLQKENLRL KNELDEAKSQ LVVADLKIQN HILIEKRKAQ EEIASLQQVI HETVEESSCS
RKQLVSEVSK LQLTLSKLQE ENALLKTQLP RDPPTDGPQI SLSTVTKTLA RKVVSQLGAD
SLSLGPDNLE ESMRKAQEDA EVLRSLVVPL EEEIKALKEK LRSTDDELQK YKEVLLKKRQ
QEPGSFEPSC DMCANYEAQL VKVEATAKNL EKQLLDSQRM LQAQKEDLAK EVEFRKEMEE
KWNEKKEEHK IKVAELTVTS QTAQQNLLEL KKTFEQIQRN VSEELIKLTR GREEVQRHLT
ALQMENENLV GKHSKHSQQL QSESINMPNT VEELHMSLLK MREDLITAKV AQEVAQEKEE
TLRYEVTLLR EQMEQESRVK EQDIAVLKNE ISGLRAQLDK YIRDHRTLAD REEKLDRLEK
QLQEIQKEKK DADSVISELR QRVMSLQQEL DTSEAVQKDF VRLSQSLQVQ LERIRQAGSE
VRWQHEEDVE ECPTCHTTFS VTKKKVHCRH CGHIFCQSCL SHVVNSGPKQ RPSRVCDVCH
TLLVQDTAPY FSQEPPHTPD
//
