ID A0A196L5V7_9MICO Unreviewed; 311 AA.
AC A0A196L5V7;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=5'-3' exonuclease {ECO:0000313|EMBL:OAN38427.1};
GN ORFNames=A4X16_03325 {ECO:0000313|EMBL:OAN38427.1};
OS Microbacterium sp. H83.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Microbacterium.
OX NCBI_TaxID=1827324 {ECO:0000313|EMBL:OAN38427.1, ECO:0000313|Proteomes:UP000078289};
RN [1] {ECO:0000313|EMBL:OAN38427.1, ECO:0000313|Proteomes:UP000078289}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H83 {ECO:0000313|EMBL:OAN38427.1,
RC ECO:0000313|Proteomes:UP000078289};
RA Lymperopoulou D., Adams R.I., Lindow S., Coil D.A., Jospin G., Eisen J.A.;
RT "Draft Genome Sequences of Staphylococcus capitis Strain H36, S. capitis
RT Strain H65, S. cohnii Strain H62, S. hominis Strain H69, Mycobacterium
RT iranicum Strain H39, Plantibacter sp. Strain H53, Pseudomonas oryzihabitans
RT Strain H72, and Microbacterium sp. Strain H83, isolated from residential
RT settings.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAN38427.1}.
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DR EMBL; LWCU01000023; OAN38427.1; -; Genomic_DNA.
DR RefSeq; WP_067120482.1; NZ_LWCU01000023.1.
DR AlphaFoldDB; A0A196L5V7; -.
DR STRING; 1827324.A4X16_03325; -.
DR OrthoDB; 9806424at2; -.
DR Proteomes; UP000078289; Unassembled WGS sequence.
DR GO; GO:0017108; F:5'-flap endonuclease activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0033567; P:DNA replication, Okazaki fragment processing; IEA:InterPro.
DR CDD; cd09898; H3TH_53EXO; 1.
DR CDD; cd09859; PIN_53EXO; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.40.50.1010; 5'-nuclease; 1.
DR InterPro; IPR020046; 5-3_exonucl_a-hlix_arch_N.
DR InterPro; IPR002421; 5-3_exonuclease.
DR InterPro; IPR036279; 5-3_exonuclease_C_sf.
DR InterPro; IPR020045; DNA_polI_H3TH.
DR InterPro; IPR038969; FEN.
DR InterPro; IPR008918; HhH2.
DR InterPro; IPR029060; PIN-like_dom_sf.
DR PANTHER; PTHR42646:SF2; DNA-DIRECTED DNA POLYMERASE; 1.
DR PANTHER; PTHR42646; FLAP ENDONUCLEASE XNI; 1.
DR Pfam; PF01367; 5_3_exonuc; 1.
DR Pfam; PF02739; 5_3_exonuc_N; 1.
DR SMART; SM00475; 53EXOc; 1.
DR SMART; SM00279; HhH2; 1.
DR SUPFAM; SSF47807; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR SUPFAM; SSF88723; PIN domain-like; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Exonuclease {ECO:0000313|EMBL:OAN38427.1};
KW Hydrolase {ECO:0000313|EMBL:OAN38427.1};
KW Nuclease {ECO:0000313|EMBL:OAN38427.1}.
FT DOMAIN 5..277
FT /note="5'-3' exonuclease"
FT /evidence="ECO:0000259|SMART:SM00475"
SQ SEQUENCE 311 AA; 32688 MW; A1C6719FE2462F72 CRC64;
MPRADKLLLL DTASLYFRAF YGVPDKVTAP DGSPINAARG LLDIVAKLVT LYEPTHVVAC
WDDDWRPQWR VDLIPSYKAH RVVEVVPAGP DVEEVPDPLE AQIPLIRETL GLLGIPIIGV
AEHEADDVIG TLATHAGMPV DIVTGDRDLF QLVDDARDVR VVYTARGMSN LEIVTDAVVV
GKYGVLPSQY ADFATMRGDA SDGLPGVAGV GEKTAATLLK EHGDLAGIRA AAEAGVGMSA
GVRAKVLAAA EYLEVAPTVV AVATDLDITA PEDPLRPLDP AEVDAATAVA EKWNLGSSMT
RAIAAVATTG G
//
