ID A0A196MGA9_9SPHN Unreviewed; 1081 AA.
AC A0A196MGA9;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Cation transporter {ECO:0000313|EMBL:OAN54320.1};
GN ORFNames=A7Q26_23960 {ECO:0000313|EMBL:OAN54320.1};
OS Sphingobium sp. TCM1.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Sphingobium.
OX NCBI_TaxID=453246 {ECO:0000313|EMBL:OAN54320.1, ECO:0000313|Proteomes:UP000078322};
RN [1] {ECO:0000313|EMBL:OAN54320.1, ECO:0000313|Proteomes:UP000078322}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TCM1 {ECO:0000313|EMBL:OAN54320.1,
RC ECO:0000313|Proteomes:UP000078322};
RA Takahashi S.;
RT "Draft Genome Sequences of Sphingobium sp. strain TCM1 and Sphingomonas sp.
RT strain TDK1, Haloalkyl Organophosphorus Flame Retardant-Degrading
RT Bacteria.";
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the resistance-nodulation-cell division (RND)
CC (TC 2.A.6) family. {ECO:0000256|ARBA:ARBA00010942}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAN54320.1}.
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DR EMBL; LXVX01000025; OAN54320.1; -; Genomic_DNA.
DR RefSeq; WP_004212878.1; NZ_LXVX01000025.1.
DR AlphaFoldDB; A0A196MGA9; -.
DR STRING; 453246.A7Q26_23960; -.
DR GeneID; 78525847; -.
DR OrthoDB; 9758757at2; -.
DR Proteomes; UP000078322; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 3.
DR InterPro; IPR027463; AcrB_DN_DC_subdom.
DR InterPro; IPR001036; Acrflvin-R.
DR InterPro; IPR004763; CusA-like.
DR NCBIfam; TIGR00914; 2A0601; 1.
DR PANTHER; PTHR32063; -; 1.
DR PANTHER; PTHR32063:SF24; CATION EFFLUX SYSTEM (ACRB_ACRD_ACRF FAMILY); 1.
DR Pfam; PF00873; ACR_tran; 1.
DR PRINTS; PR00702; ACRIFLAVINRP.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000078322};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 14..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 475..494
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 506..529
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 561..585
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 899..916
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 923..942
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 948..973
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 994..1014
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1026..1049
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 150..174
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1081 AA; 116089 MW; 18908F9388278BF3 CRC64;
MIARIVTWAV EKRWLVLLLT VIVAAIGAFS LYRLPIDAVP DITNNQVQIN VRAPALSPEL
VEKQVSFPIE TALAGTPGLE YTRSLSRNGF AQITAVFSDA TDIYFARQQV GERLRGVQEN
LPDGVNPEMG PIATGLGEVY MYTVRLDHRE DDKHKPGEPG QQPDGSYITP EGERLTTEED
KATYLRTAQD WIVTPLLKTT PGLAGVDSIG GYAKQFLVVP DVQKLASLGI TLTDLGNALE
RNNTSVGGGF VNRNGEGLAV RSDALVRNAS ELARTVIATR NGVPITVEQV ATVKTGQAIR
MGSASENGTE VVVGTAIMRI GENSRIVSTA VAEKLKTINA SLPPDVVIQP VLNRTELVNS
TIKTVAKNLS EGAVLVIVVL FLLLGNFRAA LIAALVIPIT MMLTGFGMLR AGVSANLMSL
GALDFGLIVD GAVIIVENAL RRLAEQQHHE GRLLSVKERL ATVAAAAREM IRPSVYGQAI
IILVYVPLLT LTGVEGKTFG PMALTVIIAL AFAFILSLTF VPAMIAIWLS KKVEEKDGRI
ITWLKKRYEP GLDRAMKRPT LTIGAGVGSL VVAALAFTTL GSVFLPQLDE GDLLIQSLRI
PATSVQQSQA MQVPIERMMS KQPEVQFVYS KTGTAELAAD PMPPNATDMF VILKPRKDWP
DPELPKEELV SRIEGNLAKI PGNAYEITQP IQMRFNELIA GVRGDIAVKV FGDDFNQMNR
TAEQIAAVLR RTQGAADVKV EQTTGLPMLD IRVNRDAMAR LGVTAQDVQD TVTATIGGRT
SGQIFEGDRR FPVVIRLSEA QRADIGLLQQ VQVPVAGGGY VPLSSVAEIK VVDGPNQISR
ENGKRRVVVQ ANVRGRDVGS VVADAQAAIG SQLRLPAGTY LEWGGQFENL QSASERLKLV
IPACFILILL LLYGALGSVR DAAIVFTGVP FALVGGVLLL FLRGMDFSIS AAVGFIALSG
IAVLNGLVMV SSIQDLIRSG MSREEAAHVG AMQRLRPVIM TALVASLGFV PMALGEGAGA
EVQKPLATVV IGGLISATLL TLFVLPTLYA RFGQKVIEKP EHYNEEHEGD DHGQTFVNNL
A
//
