ID   A0A196NFY1_9SPHN        Unreviewed;       359 AA.
AC   A0A196NFY1;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   24-JAN-2024, entry version 23.
DE   SubName: Full=Arsenical-resistance protein {ECO:0000313|EMBL:OAN66764.1};
GN   ORFNames=A7X12_11365 {ECO:0000313|EMBL:OAN66764.1};
OS   Sphingomonas sp. TDK1.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC   Sphingomonadaceae; Sphingomonas.
OX   NCBI_TaxID=453247 {ECO:0000313|EMBL:OAN66764.1, ECO:0000313|Proteomes:UP000078445};
RN   [1] {ECO:0000313|EMBL:OAN66764.1, ECO:0000313|Proteomes:UP000078445}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TDK1 {ECO:0000313|EMBL:OAN66764.1,
RC   ECO:0000313|Proteomes:UP000078445};
RA   Takahashi S.;
RT   "Draft Genome Sequences of Sphingobium sp. strain TCM1 and Sphingomonas sp.
RT   strain TDK1, Haloalkyl Organophosphorus Flame Retardant-Degrading
RT   Bacteria.";
RL   Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651,
CC       ECO:0000256|PIRNR:PIRNR005508}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|PIRNR:PIRNR005508}.
CC       Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59)
CC       family. {ECO:0000256|ARBA:ARBA00010110, ECO:0000256|PIRNR:PIRNR005508}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OAN66764.1}.
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DR   EMBL; LXVY01000003; OAN66764.1; -; Genomic_DNA.
DR   RefSeq; WP_064310280.1; NZ_LXVY01000003.1.
DR   AlphaFoldDB; A0A196NFY1; -.
DR   STRING; 453247.A7X12_11365; -.
DR   OrthoDB; 5290400at2; -.
DR   Proteomes; UP000078445; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0015103; F:inorganic anion transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1530.20; -; 1.
DR   InterPro; IPR004706; Arsenical-R_Acr3.
DR   InterPro; IPR002657; BilAc:Na_symport/Acr3.
DR   InterPro; IPR038770; Na+/solute_symporter_sf.
DR   NCBIfam; TIGR00832; acr3; 1.
DR   PANTHER; PTHR43057:SF1; ARSENICAL-RESISTANCE PROTEIN 3; 1.
DR   PANTHER; PTHR43057; ARSENITE EFFLUX TRANSPORTER; 1.
DR   Pfam; PF01758; SBF; 1.
DR   PIRSF; PIRSF005508; Acr3; 1.
DR   PRINTS; PR00173; EDTRNSPORT.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW   ECO:0000256|PIRNR:PIRNR005508};
KW   Membrane {ECO:0000256|PIRNR:PIRNR005508, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|PIRNR:PIRNR005508, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|PIRNR:PIRNR005508,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|PIRNR:PIRNR005508}.
FT   TRANSMEM        23..42
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        54..74
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        95..118
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        130..152
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        164..189
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        195..217
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        229..251
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        257..276
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        288..318
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        324..346
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   359 AA;  37607 MW;  BBC0EAB34AACEAFD CRC64;
     MSTVSPTLDA APARPGIGTF ERYLTLLVLL CIAAGIGLGQ LLPGVFASIV AAEVARVNLI
     VAMLIWLMII PMLLKIDFGA LGSVRQHWKG VGVTLFINWA VKPFSMAALG TLFIGWLFAP
     LLPAGEGPSY IAGLILLAAA PCTAMVFVWS NLCEGEPTYT LSQVALNDVL MVFLFAPLVG
     LLLGVASVTV PWDTLLISVL LYIVVPVIAA QLVRRAVLAR GGQAALDRLL ARLGPVSLVA
     LLATLVLLFG FQGEAIVAQP LVIALLAVPI LIQVYLNAGL AYWLSRRFGV AWCVAAPAAL
     IGASNFFELA VAAAISLFGL KSGAALATVV GVLVEVPVML SVVSIVKASR GWYERGTAA
//